SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wel'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 12 TYR A 135
ASP A 195
GLN A 129
GLU A 126
ILE A 222
None
None
AJP  A1302 (-3.6A)
None
None
1.12A 1fkbA-5welA:
undetectable
1fkbA-5welA:
7.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_2
(HIV-1 PROTEASE)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 9 ASP A 249
VAL A 248
GLY A 340
ILE A 345
ILE A 247
None
1.15A 1hpvB-5welA:
undetectable
1hpvB-5welA:
7.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_A_CYZA330_1
(GLUTAMINE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
8 / 12 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
LYS A 763
None
1.02A 1lbcA-5welA:
32.7
1lbcC-5welA:
32.3
1lbcA-5welA:
34.03
1lbcC-5welA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_B_CYZB329_1
(GLUTAMINE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
7 / 9 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
None
0.89A 1lbcB-5welA:
32.3
1lbcB-5welA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_B_CYZB329_1
(GLUTAMINE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
7 / 9 LYS A 493
PRO A 494
SER A 497
LEU A 751
SER A 754
LEU A 759
LYS A 763
None
1.26A 1lbcB-5welA:
32.3
1lbcB-5welA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_C_CYZC331_1
(GLUTAMINE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
7 / 12 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
None
0.90A 1lbcA-5welA:
32.7
1lbcC-5welA:
32.3
1lbcA-5welA:
34.03
1lbcC-5welA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_C_CYZC331_1
(GLUTAMINE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
7 / 12 LYS A 493
PRO A 494
SER A 497
LEU A 751
SER A 754
LEU A 759
LYS A 763
None
1.22A 1lbcA-5welA:
32.7
1lbcC-5welA:
32.3
1lbcA-5welA:
34.03
1lbcC-5welA:
34.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 12 LEU A 542
LEU A1228
SER A1224
THR A1170
VAL A1171
None
1.17A 1n5xA-5welA:
2.2
1n5xA-5welA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 12 LEU A 542
LEU A1228
SER A1224
VAL A1171
ALA A1166
None
1.11A 1n5xA-5welA:
2.2
1n5xA-5welA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 12 LEU A 542
LEU A1228
SER A1224
THR A1170
VAL A1171
None
1.17A 1n5xB-5welA:
2.6
1n5xB-5welA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 12 LEU A 542
LEU A1228
SER A1224
VAL A1171
ALA A1166
None
1.11A 1n5xB-5welA:
2.6
1n5xB-5welA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPO_H_TESH1010_1
(ANTI-TESTOSTERONE
(HEAVY CHAIN)
ANTI-TESTOSTERONE
(LIGHT CHAIN))
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 12 ALA A 701
GLY A 648
LEU A 703
PHE A 659
VAL A 666
None
1.11A 1vpoH-5welA:
undetectable
1vpoL-5welA:
undetectable
1vpoH-5welA:
11.90
1vpoL-5welA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 12 LEU A1015
ASN A1016
LEU A1018
ALA A1019
THR A1227
None
1.43A 2aa6A-5welA:
undetectable
2aa6A-5welA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2001_1
(SERUM ALBUMIN)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 11 LEU A 787
ASN A 791
TYR A 616
VAL A 795
GLY A 794
None
1.19A 2bxeA-5welA:
undetectable
2bxeA-5welA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 12 LEU A 787
ASN A 791
TYR A 616
VAL A 795
GLY A 794
None
1.24A 2bxeB-5welA:
3.2
2bxeB-5welA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2001_1
(SERUM ALBUMIN)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 11 LEU A 787
ASN A 791
TYR A 616
VAL A 795
GLY A 794
None
1.14A 2bxgA-5welA:
3.4
2bxgA-5welA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
4 / 6 PHE A 245
TYR A 356
GLY A 119
LYS A 118
None
1.08A 2i30A-5welA:
3.0
2i30A-5welA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
3 / 3 TRP A 766
ALA A 430
VAL A 426
None
0.81A 2izqA-5welA:
undetectable
2izqB-5welA:
undetectable
2izqA-5welA:
1.50
2izqB-5welA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 12 LEU A 146
LEU A 143
GLY A 142
VAL A 165
ALA A 223
None
1.13A 2oz7A-5welA:
undetectable
2oz7A-5welA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_1
(PROTEASE)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 11 LEU A 428
ALA A 749
GLY A 743
ILE A 476
ILE A 432
None
0.88A 3ebzA-5welA:
undetectable
3ebzA-5welA:
7.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_A_CYZA265_1
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
8 / 11 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
LYS A 763
None
1.03A 3h6tA-5welA:
32.6
3h6tC-5welA:
32.4
3h6tA-5welA:
34.03
3h6tC-5welA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_B_CYZB265_1
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
7 / 9 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
None
0.93A 3h6tB-5welA:
32.3
3h6tB-5welA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_B_CYZB265_1
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
7 / 9 LYS A 493
PRO A 494
MET A 496
SER A 497
SER A 754
LEU A 759
LYS A 763
None
1.03A 3h6tB-5welA:
32.3
3h6tB-5welA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_C_CYZC265_1
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
8 / 11 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
LYS A 763
None
1.00A 3h6tA-5welA:
32.6
3h6tC-5welA:
32.4
3h6tA-5welA:
34.03
3h6tC-5welA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
4 / 5 LYS A 493
PRO A 494
LEU A 751
SER A 754
None
0.61A 3ijxH-5welA:
32.3
3ijxH-5welA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IK6_B_HCZB262_1
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
6 / 10 ILE A 481
PRO A 494
SER A 497
SER A 729
LYS A 730
GLY A 731
None
0.73A 3ik6B-5welA:
32.5
3ik6E-5welA:
32.9
3ik6B-5welA:
66.93
3ik6E-5welA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 10 ILE A 481
PRO A 494
SER A 497
SER A 729
GLY A 731
None
0.72A 3ik6B-5welA:
32.5
3ik6E-5welA:
32.9
3ik6B-5welA:
66.93
3ik6E-5welA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 10 ILE A 481
PRO A 494
SER A 729
LYS A 730
GLY A 731
None
0.80A 3ik6B-5welA:
32.5
3ik6E-5welA:
32.9
3ik6B-5welA:
66.93
3ik6E-5welA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_B_TRUB800_1
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
8 / 12 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
LYS A 763
None
0.99A 3iltB-5welA:
29.3
3iltE-5welA:
28.8
3iltB-5welA:
66.93
3iltE-5welA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_E_TRUE800_1
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
7 / 10 LYS A 493
MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
LYS A 763
None
1.00A 3iltB-5welA:
29.3
3iltE-5welA:
28.8
3iltB-5welA:
66.93
3iltE-5welA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_E_TRUE800_1
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
7 / 10 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
None
0.84A 3iltB-5welA:
29.3
3iltE-5welA:
28.8
3iltB-5welA:
66.93
3iltE-5welA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_H_TRUH800_1
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
3 / 3 ILE A 481
SER A 497
SER A 729
None
0.32A 3iltH-5welA:
28.5
3iltH-5welA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 11 ILE A 481
PRO A 494
SER A 497
SER A 729
GLY A 731
None
0.70A 3iluB-5welA:
32.7
3iluE-5welA:
32.4
3iluB-5welA:
66.93
3iluE-5welA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 11 ILE A 481
PRO A 494
SER A 729
LYS A 730
GLY A 731
None
0.82A 3iluB-5welA:
32.7
3iluE-5welA:
32.4
3iluB-5welA:
66.93
3iluE-5welA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
4 / 5 LYS A 493
PRO A 494
LEU A 751
SER A 754
None
0.73A 3iluH-5welA:
32.4
3iluH-5welA:
66.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
3 / 3 ALA A 430
VAL A 426
TRP A 766
None
0.83A 3l8lA-5welA:
undetectable
3l8lB-5welA:
undetectable
3l8lA-5welA:
1.50
3l8lB-5welA:
2.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_B_PZIB800_0
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
7 / 10 TYR A 424
PRO A 494
MET A 496
SER A 497
SER A 754
LEU A 759
ASP A 760
None
0.67A 3lsfB-5welA:
32.7
3lsfE-5welA:
32.5
3lsfB-5welA:
66.93
3lsfE-5welA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_E_PZIE800_0
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
6 / 10 PRO A 494
MET A 496
SER A 497
SER A 754
LEU A 759
ASP A 760
None
0.73A 3lsfB-5welA:
32.7
3lsfE-5welA:
32.5
3lsfB-5welA:
66.93
3lsfE-5welA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_E_PZIE800_0
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
6 / 10 PRO A 494
MET A 496
SER A 497
SER A 754
LEU A 759
LYS A 763
None
0.79A 3lsfB-5welA:
32.7
3lsfE-5welA:
32.5
3lsfB-5welA:
66.93
3lsfE-5welA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
7 / 8 TYR A 424
PRO A 494
MET A 496
SER A 497
SER A 754
LEU A 759
ASP A 760
None
0.71A 3lsfH-5welA:
32.1
3lsfH-5welA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
7 / 8 TYR A 424
PRO A 494
MET A 496
SER A 497
SER A 754
LEU A 759
LYS A 763
None
0.79A 3lsfH-5welA:
32.1
3lsfH-5welA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
4 / 7 TYR A 424
MET A 496
LEU A 759
ASP A 760
None
0.53A 3lslA-5welA:
32.2
3lslD-5welA:
32.5
3lslA-5welA:
66.67
3lslD-5welA:
66.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
4 / 7 TYR A 424
MET A 496
LEU A 759
LYS A 763
None
0.94A 3lslA-5welA:
32.2
3lslD-5welA:
32.5
3lslA-5welA:
66.67
3lslD-5welA:
66.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_D_PZID800_0
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
4 / 7 TYR A 424
MET A 496
LEU A 759
ASP A 760
None
0.50A 3lslA-5welA:
32.2
3lslD-5welA:
32.5
3lslA-5welA:
66.67
3lslD-5welA:
66.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_D_PZID800_0
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
4 / 7 TYR A 424
MET A 496
LEU A 759
LYS A 763
None
0.92A 3lslA-5welA:
32.2
3lslD-5welA:
32.5
3lslA-5welA:
66.67
3lslD-5welA:
66.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
4 / 6 TYR A 424
MET A 496
LEU A 759
ASP A 760
None
0.48A 3lslG-5welA:
32.2
3lslG-5welA:
66.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
4 / 6 TYR A 424
MET A 496
LEU A 759
LYS A 763
None
0.85A 3lslG-5welA:
32.2
3lslG-5welA:
66.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M7R_A_VDXA425_1
(VITAMIN D3 RECEPTOR)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 12 VAL A 543
SER A 544
SER A 576
CYH A 589
VAL A 601
None
1.28A 3m7rA-5welA:
undetectable
3m7rA-5welA:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
4 / 7 TYR A 270
VAL A 248
MET A  33
ARG A 198
None
1.28A 3ms9B-5welA:
undetectable
3ms9B-5welA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_SALB900_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
4 / 5 VAL A 255
TYR A 250
ILE A 278
ALA A 283
None
0.84A 3n8yB-5welA:
undetectable
3n8yB-5welA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
3 / 3 GLN A1186
THR A1185
LEU A 521
None
0.74A 3ondA-5welA:
5.1
3ondA-5welA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_2
(ADENOSYLHOMOCYSTEINA
SE)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
3 / 3 GLN A1186
THR A1185
LEU A 521
None
0.72A 3ondB-5welA:
undetectable
3ondB-5welA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 9 TYR A 533
ILE A 529
THR A 609
ILE A 612
ILE A 613
None
1.17A 3p4wB-5welA:
4.0
3p4wB-5welA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 10 TYR A 533
ILE A 529
THR A 609
ILE A 612
ILE A 613
None
1.17A 3p4wD-5welA:
4.0
3p4wD-5welA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 10 TYR A 533
ILE A 529
THR A 609
ILE A 612
ILE A 613
None
1.17A 3p4wE-5welA:
4.0
3p4wE-5welA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
3 / 3 ILE A 712
VAL A 690
ARG A 694
None
0.39A 3p73A-5welA:
undetectable
3p73A-5welA:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROP_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
4 / 6 LEU A 122
GLU A 126
TRP A 158
SER A 152
None
1.47A 3ropA-5welA:
undetectable
3ropA-5welA:
13.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_A_CYZA266_1
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
8 / 9 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
ASP A 760
None
0.80A 3tkdA-5welA:
32.6
3tkdA-5welA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_A_CYZA266_1
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
8 / 9 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
LYS A 763
None
0.91A 3tkdA-5welA:
32.6
3tkdA-5welA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_A_CYZA266_2
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 5 ILE A 481
PRO A 494
SER A 729
LYS A 730
GLY A 731
None
0.85A 3tkdB-5welA:
31.6
3tkdB-5welA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 5 ILE A 481
PRO A 494
SER A 729
LYS A 730
GLY A 731
None
0.81A 3tkdA-5welA:
32.6
3tkdA-5welA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_B_CYZB267_2
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
8 / 9 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
ASP A 760
None
0.86A 3tkdB-5welA:
31.6
3tkdB-5welA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_B_CYZB267_2
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
8 / 9 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
LYS A 763
None
0.96A 3tkdB-5welA:
31.6
3tkdB-5welA:
33.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
4 / 8 ILE A 459
ARG A 453
PRO A 737
VAL A 488
None
1.23A 4f4dB-5welA:
4.5
4f4dB-5welA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
4 / 7 THR A 736
LEU A 748
GLN A 756
LEU A 753
None
1.13A 4ib4A-5welA:
4.0
4ib4A-5welA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
4 / 7 VAL A 291
MET A 292
ALA A 295
PHE A 296
None
0.96A 4lb2A-5welA:
undetectable
4lb2A-5welA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA601_1
(SERUM ALBUMIN)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 12 LEU A 787
ASN A 791
TYR A 616
VAL A 795
GLY A 794
None
1.11A 4ot2A-5welA:
3.5
4ot2A-5welA:
20.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
4 / 5 ILE A 358
HIS A 219
TYR A 135
VAL A 149
None
AJP  A1302 (-4.3A)
None
None
1.03A 4s0vA-5welA:
4.7
4s0vA-5welA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
4 / 5 THR A 275
ALA A 276
THR A 277
TYR A 250
None
1.40A 5ecmA-5welA:
undetectable
5ecmA-5welA:
18.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
4 / 8 ASP A 519
PRO A 520
TYR A 616
SER A 788
None
0.76A 5l1fA-5welA:
50.3
5l1fB-5welA:
55.3
5l1fA-5welA:
78.61
5l1fB-5welA:
78.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L1F_B_6ZPB902_1
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
6 / 9 ASP A 519
PRO A 520
TYR A 616
LEU A 620
SER A 788
ASN A 791
None
1.11A 5l1fB-5welA:
55.3
5l1fB-5welA:
78.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L1F_B_6ZPB902_1
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
6 / 9 ASP A 519
PRO A 520
TYR A 616
LEU A 620
SER A 790
ASN A 791
None
1.28A 5l1fB-5welA:
55.3
5l1fB-5welA:
78.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
4 / 7 SER A 516
ASP A 519
PRO A 520
TYR A 616
None
0.72A 5l1fC-5welA:
55.6
5l1fC-5welA:
78.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L1F_D_6ZPD902_1
(GLUTAMATE RECEPTOR 2)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
6 / 10 PHE A 517
ASP A 519
PRO A 520
TYR A 616
LEU A 620
SER A 788
None
1.35A 5l1fD-5welA:
55.6
5l1fD-5welA:
78.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
4 / 4 GLN A1189
THR A1185
THR A1093
LEU A1116
None
1.46A 5m5kA-5welA:
4.8
5m5kA-5welA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
4 / 4 GLN A1189
THR A1185
THR A1093
LEU A1116
None
1.45A 5m5kC-5welA:
4.2
5m5kC-5welA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
4 / 4 GLN A1189
THR A1185
THR A1093
LEU A1116
None
1.48A 5m66B-5welA:
4.5
5m66B-5welA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
4 / 8 ALA A 288
PHE A 258
LEU A 341
VAL A  31
None
0.72A 5nujA-5welA:
undetectable
5nujA-5welA:
5.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
4 / 8 GLY A 142
GLN A 147
LEU A 143
THR A 145
None
1.06A 5sxqB-5welA:
undetectable
5sxqB-5welA:
22.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WEO_A_CYZA1302_1
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 10 ILE A 481
PRO A 494
SER A 497
SER A 729
GLY A 731
None
0.44A 5weoA-5welA:
54.3
5weoD-5welA:
54.3
5weoA-5welA:
81.51
5weoD-5welA:
81.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WEO_A_CYZA1302_1
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 10 PRO A 494
MET A 496
SER A 497
ASP A 760
LYS A 763
None
0.65A 5weoA-5welA:
54.3
5weoD-5welA:
54.3
5weoA-5welA:
81.51
5weoD-5welA:
81.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WEO_B_CYZB1302_1
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 9 PRO A 494
MET A 496
SER A 497
ASP A 760
LYS A 763
None
0.67A 5weoB-5welA:
54.3
5weoC-5welA:
35.0
5weoB-5welA:
81.51
5weoC-5welA:
81.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WEO_C_CYZC1302_1
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 9 PRO A 494
MET A 496
SER A 497
ASP A 760
LYS A 763
None
0.67A 5weoB-5welA:
54.3
5weoC-5welA:
35.0
5weoB-5welA:
81.51
5weoC-5welA:
81.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WEO_D_CYZD1302_1
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
5 / 9 PRO A 494
MET A 496
SER A 497
ASP A 760
LYS A 763
None
0.67A 5weoA-5welA:
54.3
5weoD-5welA:
54.3
5weoA-5welA:
81.51
5weoD-5welA:
81.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DLZ_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
7 / 10 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
ASP A 760
LYS A 763
None
0.76A 6dlzA-5welA:
53.6
6dlzD-5welA:
53.1
6dlzA-5welA:
100.00
6dlzD-5welA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DLZ_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
7 / 10 MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
ASP A 760
LYS A 763
None
0.83A 6dlzB-5welA:
53.1
6dlzC-5welA:
53.5
6dlzB-5welA:
100.00
6dlzC-5welA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DLZ_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
7 / 10 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
ASP A 760
LYS A 763
None
0.72A 6dlzB-5welA:
53.1
6dlzC-5welA:
53.5
6dlzB-5welA:
100.00
6dlzC-5welA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DLZ_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
8 / 11 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
ASP A 760
LYS A 763
None
0.80A 6dlzA-5welA:
53.6
6dlzD-5welA:
53.1
6dlzA-5welA:
100.00
6dlzD-5welA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM0_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
7 / 9 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
ASP A 760
LYS A 763
None
0.74A 6dm0A-5welA:
43.2
6dm0D-5welA:
53.0
6dm0A-5welA:
100.00
6dm0D-5welA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM0_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
6 / 10 MET A 496
SER A 497
LEU A 751
LEU A 759
ASP A 760
LYS A 763
None
0.81A 6dm0B-5welA:
53.0
6dm0C-5welA:
43.2
6dm0B-5welA:
100.00
6dm0C-5welA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM0_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
7 / 9 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
ASP A 760
LYS A 763
None
0.75A 6dm0B-5welA:
53.1
6dm0C-5welA:
43.2
6dm0B-5welA:
100.00
6dm0C-5welA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM0_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
6 / 9 MET A 496
SER A 497
LEU A 751
LEU A 759
ASP A 760
LYS A 763
None
0.80A 6dm0A-5welA:
43.2
6dm0D-5welA:
53.0
6dm0A-5welA:
100.00
6dm0D-5welA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM1_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
7 / 10 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
ASP A 760
LYS A 763
None
0.75A 6dm1A-5welA:
53.6
6dm1D-5welA:
53.1
6dm1A-5welA:
100.00
6dm1D-5welA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM1_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
7 / 10 MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
ASP A 760
LYS A 763
None
0.82A 6dm1B-5welA:
53.1
6dm1C-5welA:
53.6
6dm1B-5welA:
100.00
6dm1C-5welA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM1_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
7 / 10 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
ASP A 760
LYS A 763
None
0.73A 6dm1B-5welA:
53.1
6dm1C-5welA:
53.6
6dm1B-5welA:
100.00
6dm1C-5welA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM1_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
8 / 11 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
ASP A 760
LYS A 763
None
0.81A 6dm1A-5welA:
53.6
6dm1D-5welA:
53.1
6dm1A-5welA:
100.00
6dm1D-5welA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM2_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
7 / 9 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
ASP A 760
LYS A 763
None
0.72A 6dm2A-5welA:
53.6
6dm2D-5welA:
53.2
6dm2A-5welA:
100.00
6dm2D-5welA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM2_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
7 / 10 MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
ASP A 760
LYS A 763
None
0.86A 6dm2B-5welA:
53.2
6dm2C-5welA:
53.6
6dm2B-5welA:
100.00
6dm2C-5welA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM2_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
7 / 9 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
ASP A 760
LYS A 763
None
0.70A 6dm2B-5welA:
53.2
6dm2C-5welA:
53.6
6dm2B-5welA:
100.00
6dm2C-5welA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM2_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
7 / 10 MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
ASP A 760
LYS A 763
None
0.85A 6dm2A-5welA:
53.6
6dm2D-5welA:
53.2
6dm2A-5welA:
100.00
6dm2D-5welA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_B_ADNB502_2
(-)
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus
musculus;
Rattus
norvegicus)
4 / 4 GLN A1189
THR A1185
THR A1093
LEU A1116
None
1.45A 6f3mB-5welA:
4.2
6f3mB-5welA:
19.36