SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5weo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FAP_A_RAPA108_2
(FK506-BINDING
PROTEIN
FRAP)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		4 / 8 LEU A1113
SER A1147
PHE A1106
GLY A1151
 None
 0.92A 1fapB-5weoA:
undetectable		 1fapB-5weoA:
6.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_D_D16D417_1
(THYMIDYLATE SYNTHASE)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 ILE A1121
LEU A1011
GLY A1193
PHE A1141
MET A1199
 None
 1.13A 1hvyD-5weoA:
undetectable		 1hvyD-5weoA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_2
(HIV-1 PROTEASE)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 11 LEU A1195
GLY A1015
ALA A1016
ILE A1187
VAL A1194
 None
 0.88A 1hxwB-5weoA:
undetectable		 1hxwB-5weoA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG2_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 GLY A 470
GLY A 217
GLY A 465
ALA A 472
VAL A 396
 None
 1.18A 1jg2A-5weoA:
undetectable		 1jg2A-5weoA:
12.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_A_CYZA330_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 LYS A 493
MET A 496
LEU A 751
SER A 754
LEU A 759
 None
CYZ  A1302 (-4.3A)
None
CYZ  A1302 ( 4.1A)
None
 0.88A 1lbcA-5weoA:
25.1
1lbcC-5weoA:
25.0		 1lbcA-5weoA:
34.03
1lbcC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_A_CYZA330_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 LYS A 493
MET A 496
LEU A 751
SER A 754
LYS A 763
 None
CYZ  A1302 (-4.3A)
None
CYZ  A1302 ( 4.1A)
CYZ  A1302 (-2.9A)
 0.96A 1lbcA-5weoA:
25.1
1lbcC-5weoA:
25.0		 1lbcA-5weoA:
34.03
1lbcC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_A_CYZA330_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 LYS A 493
MET A 496
SER A 497
LEU A 751
LEU A 759
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
None
 0.72A 1lbcA-5weoA:
25.1
1lbcC-5weoA:
25.0		 1lbcA-5weoA:
34.03
1lbcC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_A_CYZA330_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 LYS A 493
MET A 496
SER A 497
LEU A 751
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 (-2.9A)
 0.96A 1lbcA-5weoA:
25.1
1lbcC-5weoA:
25.0		 1lbcA-5weoA:
34.03
1lbcC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_A_CYZA330_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 LYS A 493
PRO A 494
MET A 496
LEU A 751
SER A 754
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
None
CYZ  A1302 ( 4.1A)
 0.93A 1lbcA-5weoA:
25.1
1lbcC-5weoA:
25.0		 1lbcA-5weoA:
34.03
1lbcC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_A_CYZA330_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
 0.66A 1lbcA-5weoA:
25.1
1lbcC-5weoA:
25.0		 1lbcA-5weoA:
34.03
1lbcC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_B_CYZB329_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LYS A 493
MET A 496
LEU A 751
SER A 754
LEU A 759
 None
CYZ  A1302 (-4.3A)
None
CYZ  A1302 ( 4.1A)
None
 0.85A 1lbcB-5weoA:
24.9		 1lbcB-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_B_CYZB329_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LYS A 493
MET A 496
SER A 497
LEU A 751
LEU A 759
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
None
 0.70A 1lbcB-5weoA:
24.9		 1lbcB-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_B_CYZB329_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LYS A 493
MET A 496
SER A 497
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 (-2.9A)
 1.30A 1lbcB-5weoA:
24.9		 1lbcB-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_B_CYZB329_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LYS A 493
MET A 496
SER A 754
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-2.9A)
 1.19A 1lbcB-5weoA:
24.9		 1lbcB-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_B_CYZB329_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LYS A 493
PRO A 494
MET A 496
LEU A 751
SER A 754
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
None
CYZ  A1302 ( 4.1A)
 0.94A 1lbcB-5weoA:
24.9		 1lbcB-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_B_CYZB329_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
 0.64A 1lbcB-5weoA:
24.9		 1lbcB-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_C_CYZC331_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 LYS A 493
MET A 496
SER A 497
LEU A 751
LEU A 759
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
None
 0.66A 1lbcA-5weoA:
25.1
1lbcC-5weoA:
25.0		 1lbcA-5weoA:
34.03
1lbcC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_C_CYZC331_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 LYS A 493
MET A 496
SER A 497
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 (-2.9A)
 1.20A 1lbcA-5weoA:
25.1
1lbcC-5weoA:
25.0		 1lbcA-5weoA:
34.03
1lbcC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_C_CYZC331_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 LYS A 493
MET A 496
SER A 754
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-2.9A)
 1.16A 1lbcA-5weoA:
25.1
1lbcC-5weoA:
25.0		 1lbcA-5weoA:
34.03
1lbcC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_C_CYZC331_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
 0.65A 1lbcA-5weoA:
25.1
1lbcC-5weoA:
25.0		 1lbcA-5weoA:
34.03
1lbcC-5weoA:
34.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PWY_E_AC2E290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 10 GLY A 598
PHE A 571
VAL A 601
GLY A 602
VAL A 543
 None
 0.89A 1pwyE-5weoA:
3.0		 1pwyE-5weoA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_1
(PROTEASE RETROPEPSIN)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 10 LEU A1195
GLY A1015
ALA A1016
ILE A1187
VAL A1194
 None
 0.94A 1t3rA-5weoA:
undetectable		 1t3rA-5weoA:
8.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3Q_E_2DIE290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 10 GLY A 598
PHE A 571
VAL A 601
GLY A 602
VAL A 543
 None
 0.91A 1v3qE-5weoA:
undetectable		 1v3qE-5weoA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		4 / 7 PHE A  29
MET A  33
VAL A  34
SER A  37
 None
 1.00A 1wrlA-5weoA:
undetectable
1wrlB-5weoA:
undetectable		 1wrlA-5weoA:
6.21
1wrlB-5weoA:
6.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		4 / 7 ALA A 223
TYR A 135
ILE A 222
ILE A 193
 None
 1.15A 2zm7A-5weoA:
undetectable		 2zm7A-5weoA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_2
(PROTEASE)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LEU A1114
ILE A1105
GLY A1151
ILE A1152
ALA A1144
 None
 0.99A 3el0B-5weoA:
undetectable		 3el0B-5weoA:
7.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_A_CYZA265_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 11 LYS A 493
MET A 496
SER A 497
LEU A 751
LEU A 759
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
None
 0.69A 3h6tA-5weoA:
25.6
3h6tC-5weoA:
25.4		 3h6tA-5weoA:
34.03
3h6tC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_A_CYZA265_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 11 LYS A 493
MET A 496
SER A 497
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 (-2.9A)
 0.99A 3h6tA-5weoA:
25.6
3h6tC-5weoA:
25.4		 3h6tA-5weoA:
34.03
3h6tC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_A_CYZA265_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 11 LYS A 493
MET A 496
SER A 754
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-2.9A)
 0.97A 3h6tA-5weoA:
25.6
3h6tC-5weoA:
25.4		 3h6tA-5weoA:
34.03
3h6tC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_A_CYZA265_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 11 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
 0.68A 3h6tA-5weoA:
25.6
3h6tC-5weoA:
25.4		 3h6tA-5weoA:
34.03
3h6tC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_B_CYZB265_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LYS A 493
MET A 496
SER A 497
LEU A 751
LEU A 759
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
None
 0.66A 3h6tB-5weoA:
25.2		 3h6tB-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_B_CYZB265_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
 0.67A 3h6tB-5weoA:
25.2		 3h6tB-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_C_CYZC265_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 11 LYS A 493
MET A 496
SER A 497
LEU A 751
LEU A 759
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
None
 0.68A 3h6tA-5weoA:
25.6
3h6tC-5weoA:
25.4		 3h6tA-5weoA:
34.03
3h6tC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_C_CYZC265_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 11 LYS A 493
MET A 496
SER A 497
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 (-2.9A)
 0.94A 3h6tA-5weoA:
25.6
3h6tC-5weoA:
25.4		 3h6tA-5weoA:
34.03
3h6tC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_C_CYZC265_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 11 LYS A 493
MET A 496
SER A 754
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-2.9A)
 0.91A 3h6tA-5weoA:
25.6
3h6tC-5weoA:
25.4		 3h6tA-5weoA:
34.03
3h6tC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_C_CYZC265_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 11 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
 0.63A 3h6tA-5weoA:
25.6
3h6tC-5weoA:
25.4		 3h6tA-5weoA:
34.03
3h6tC-5weoA:
34.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_1
(O-METHYLTRANSFERASE)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		3 / 3 ASP A  78
PHE A 101
SER A 139
 None
 0.98A 3i5uB-5weoA:
undetectable		 3i5uB-5weoA:
16.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 10 ILE A 481
PRO A 494
SER A 497
SER A 729
GLY A 731
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-3.2A)
None
None
 0.55A 3ijxB-5weoA:
25.2
3ijxD-5weoA:
25.2		 3ijxB-5weoA:
66.93
3ijxD-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 10 LYS A 493
PRO A 494
SER A 497
LEU A 751
SER A 754
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
 0.90A 3ijxB-5weoA:
25.2
3ijxD-5weoA:
25.2		 3ijxB-5weoA:
66.93
3ijxD-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IJX_D_HCZD800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LYS A 493
PRO A 494
SER A 497
LEU A 751
SER A 754
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
 0.94A 3ijxB-5weoA:
25.2
3ijxD-5weoA:
25.2		 3ijxB-5weoA:
66.93
3ijxD-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 5 LYS A 493
PRO A 494
SER A 497
LEU A 751
SER A 754
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
 0.92A 3ijxH-5weoA:
24.8		 3ijxH-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IK6_B_HCZB262_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 10 ILE A 481
PRO A 494
SER A 497
SER A 729
LYS A 730
GLY A 731
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-3.2A)
None
GLU  A1301 ( 3.7A)
None
 0.60A 3ik6B-5weoA:
25.3
3ik6E-5weoA:
25.2		 3ik6B-5weoA:
66.93
3ik6E-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 10 ILE A 481
PRO A 494
SER A 497
SER A 729
LYS A 730
GLY A 731
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-3.2A)
None
GLU  A1301 ( 3.7A)
None
 0.69A 3ik6B-5weoA:
25.3
3ik6E-5weoA:
25.2		 3ik6B-5weoA:
66.93
3ik6E-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IK6_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		4 / 4 LYS A 493
SER A 497
LEU A 751
SER A 754
 None
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
 0.92A 3ik6H-5weoA:
25.0		 3ik6H-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_B_TRUB800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 12 LYS A 493
MET A 496
LEU A 751
SER A 754
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
None
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-2.9A)
 0.96A 3iltB-5weoA:
21.4
3iltE-5weoA:
21.3		 3iltB-5weoA:
66.93
3iltE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_B_TRUB800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 12 LYS A 493
MET A 496
SER A 497
LEU A 751
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
None
CYZ  A1302 (-2.9A)
 1.02A 3iltB-5weoA:
21.4
3iltE-5weoA:
21.3		 3iltB-5weoA:
66.93
3iltE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_B_TRUB800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 LYS A 493
PRO A 494
MET A 496
LEU A 751
SER A 754
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
None
CYZ  A1302 ( 4.1A)
 0.97A 3iltB-5weoA:
21.4
3iltE-5weoA:
21.3		 3iltB-5weoA:
66.93
3iltE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_B_TRUB800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
 0.81A 3iltB-5weoA:
21.4
3iltE-5weoA:
21.3		 3iltB-5weoA:
66.93
3iltE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_E_TRUE800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 10 LYS A 493
MET A 496
LEU A 751
SER A 754
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
None
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-2.9A)
 1.05A 3iltB-5weoA:
21.4
3iltE-5weoA:
21.3		 3iltB-5weoA:
66.93
3iltE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_E_TRUE800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 10 LYS A 493
MET A 496
SER A 497
LEU A 751
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
None
CYZ  A1302 (-2.9A)
 1.05A 3iltB-5weoA:
21.4
3iltE-5weoA:
21.3		 3iltB-5weoA:
66.93
3iltE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_E_TRUE800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 10 LYS A 493
PRO A 494
MET A 496
LEU A 751
SER A 754
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
None
CYZ  A1302 ( 4.1A)
 0.98A 3iltB-5weoA:
21.4
3iltE-5weoA:
21.3		 3iltB-5weoA:
66.93
3iltE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_E_TRUE800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 10 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
 0.78A 3iltB-5weoA:
21.4
3iltE-5weoA:
21.3		 3iltB-5weoA:
66.93
3iltE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_H_TRUH800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		3 / 3 ILE A 481
SER A 497
SER A 729
 None
CYZ  A1302 (-3.2A)
None
 0.39A 3iltH-5weoA:
21.0		 3iltH-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 10 ILE A 481
PRO A 494
SER A 497
SER A 729
GLY A 731
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-3.2A)
None
None
 0.59A 3iluB-5weoA:
25.3
3iluE-5weoA:
25.2		 3iluB-5weoA:
66.93
3iluE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 10 LYS A 493
PRO A 494
SER A 497
LEU A 751
SER A 754
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
 0.89A 3iluB-5weoA:
25.3
3iluE-5weoA:
25.2		 3iluB-5weoA:
66.93
3iluE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 11 ILE A 481
PRO A 494
SER A 497
SER A 729
LYS A 730
GLY A 731
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-3.2A)
None
GLU  A1301 ( 3.7A)
None
 0.68A 3iluB-5weoA:
25.3
3iluE-5weoA:
25.2		 3iluB-5weoA:
66.93
3iluE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 11 LYS A 493
PRO A 494
SER A 497
LEU A 751
SER A 754
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
 0.93A 3iluB-5weoA:
25.3
3iluE-5weoA:
25.2		 3iluB-5weoA:
66.93
3iluE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 5 LYS A 493
PRO A 494
SER A 497
LEU A 751
SER A 754
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
 0.97A 3iluH-5weoA:
25.0		 3iluH-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_B_PZIB800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 10 TYR A 424
PRO A 494
MET A 496
SER A 497
LEU A 759
ASP A 760
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 (-3.8A)
 0.79A 3lsfB-5weoA:
25.2
3lsfE-5weoA:
25.1		 3lsfB-5weoA:
66.93
3lsfE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_B_PZIB800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 10 TYR A 424
PRO A 494
MET A 496
SER A 754
LEU A 759
ASP A 760
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-3.8A)
 0.93A 3lsfB-5weoA:
25.2
3lsfE-5weoA:
25.1		 3lsfB-5weoA:
66.93
3lsfE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_E_PZIE800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 10 PRO A 494
MET A 496
SER A 497
LEU A 759
ASP A 760
 CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 (-3.8A)
 0.77A 3lsfB-5weoA:
25.2
3lsfE-5weoA:
25.1		 3lsfB-5weoA:
66.93
3lsfE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_E_PZIE800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 10 PRO A 494
MET A 496
SER A 497
LEU A 759
LYS A 763
 CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 (-2.9A)
 0.97A 3lsfB-5weoA:
25.2
3lsfE-5weoA:
25.1		 3lsfB-5weoA:
66.93
3lsfE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_E_PZIE800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 10 PRO A 494
MET A 496
SER A 754
LEU A 759
LYS A 763
 CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-2.9A)
 1.03A 3lsfB-5weoA:
25.2
3lsfE-5weoA:
25.1		 3lsfB-5weoA:
66.93
3lsfE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 8 TYR A 424
MET A 496
SER A 497
LEU A 759
ASP A 760
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 (-3.8A)
 0.68A 3lsfH-5weoA:
24.6		 3lsfH-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 8 TYR A 424
MET A 496
SER A 497
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 (-2.9A)
 1.05A 3lsfH-5weoA:
24.6		 3lsfH-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 8 TYR A 424
MET A 496
SER A 754
LEU A 759
ASP A 760
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-3.8A)
 0.83A 3lsfH-5weoA:
24.6		 3lsfH-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 8 TYR A 424
MET A 496
SER A 754
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-2.9A)
 1.02A 3lsfH-5weoA:
24.6		 3lsfH-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 8 TYR A 424
PRO A 494
MET A 496
SER A 497
ASP A 760
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
CYZ  A1302 (-3.8A)
 0.83A 3lsfH-5weoA:
24.6		 3lsfH-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 8 TYR A 424
PRO A 494
MET A 496
SER A 497
LYS A 763
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
CYZ  A1302 (-2.9A)
 1.02A 3lsfH-5weoA:
24.6		 3lsfH-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 8 TYR A 424
PRO A 494
MET A 496
SER A 754
ASP A 760
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 ( 4.1A)
CYZ  A1302 (-3.8A)
 0.98A 3lsfH-5weoA:
24.6		 3lsfH-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 8 TYR A 424
PRO A 494
MET A 496
SER A 754
LYS A 763
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 ( 4.1A)
CYZ  A1302 (-2.9A)
 1.08A 3lsfH-5weoA:
24.6		 3lsfH-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		4 / 7 TYR A 424
MET A 496
LEU A 759
ASP A 760
 None
CYZ  A1302 (-4.3A)
None
CYZ  A1302 (-3.8A)
 0.56A 3lslA-5weoA:
25.4
3lslD-5weoA:
25.3		 3lslA-5weoA:
66.67
3lslD-5weoA:
66.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		4 / 7 TYR A 424
MET A 496
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
None
CYZ  A1302 (-2.9A)
 1.22A 3lslA-5weoA:
25.4
3lslD-5weoA:
25.3		 3lslA-5weoA:
66.67
3lslD-5weoA:
66.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_D_PZID800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		4 / 7 TYR A 424
MET A 496
LEU A 759
ASP A 760
 None
CYZ  A1302 (-4.3A)
None
CYZ  A1302 (-3.8A)
 0.50A 3lslA-5weoA:
25.4
3lslD-5weoA:
25.3		 3lslA-5weoA:
66.67
3lslD-5weoA:
66.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_D_PZID800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		4 / 7 TYR A 424
MET A 496
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
None
CYZ  A1302 (-2.9A)
 1.20A 3lslA-5weoA:
25.4
3lslD-5weoA:
25.3		 3lslA-5weoA:
66.67
3lslD-5weoA:
66.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		4 / 6 TYR A 424
MET A 496
LEU A 759
ASP A 760
 None
CYZ  A1302 (-4.3A)
None
CYZ  A1302 (-3.8A)
 0.57A 3lslG-5weoA:
24.8		 3lslG-5weoA:
66.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_A_T44A128_1
(TRANSTHYRETIN)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 MET A1009
THR A1012
ALA A1196
LEU A1135
VAL A1192
 None
 1.34A 3ozkA-5weoA:
undetectable		 3ozkA-5weoA:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		3 / 3 ILE A 712
VAL A 690
ARG A 694
 None
 0.57A 3p73A-5weoA:
undetectable		 3p73A-5weoA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		4 / 7 GLN A  24
GLU A  25
PHE A  76
PRO A  99
 None
 1.28A 3ql6A-5weoA:
undetectable		 3ql6A-5weoA:
20.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_A_CYZA266_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 9 LYS A 493
MET A 496
LEU A 751
SER A 754
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
None
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-2.9A)
 0.90A 3tkdA-5weoA:
25.4		 3tkdA-5weoA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_A_CYZA266_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 9 LYS A 493
MET A 496
SER A 497
LEU A 751
LEU A 759
ASP A 760
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
None
CYZ  A1302 (-3.8A)
 0.67A 3tkdA-5weoA:
25.4		 3tkdA-5weoA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_A_CYZA266_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 9 LYS A 493
MET A 496
SER A 497
LEU A 751
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
None
CYZ  A1302 (-2.9A)
 0.90A 3tkdA-5weoA:
25.4		 3tkdA-5weoA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_A_CYZA266_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LYS A 493
PRO A 494
MET A 496
LEU A 751
SER A 754
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
None
CYZ  A1302 ( 4.1A)
 0.91A 3tkdA-5weoA:
25.4		 3tkdA-5weoA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_A_CYZA266_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
 0.66A 3tkdA-5weoA:
25.4		 3tkdA-5weoA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_A_CYZA266_2
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 5 ILE A 481
PRO A 494
SER A 729
LYS A 730
GLY A 731
 None
CYZ  A1302 (-4.5A)
None
GLU  A1301 ( 3.7A)
None
 0.61A 3tkdB-5weoA:
24.5		 3tkdB-5weoA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 5 ILE A 481
PRO A 494
SER A 729
LYS A 730
GLY A 731
 None
CYZ  A1302 (-4.5A)
None
GLU  A1301 ( 3.7A)
None
 0.59A 3tkdA-5weoA:
25.4		 3tkdA-5weoA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_B_CYZB267_2
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 9 LYS A 493
MET A 496
LEU A 751
SER A 754
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
None
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-2.9A)
 0.91A 3tkdB-5weoA:
24.5		 3tkdB-5weoA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_B_CYZB267_2
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 9 LYS A 493
MET A 496
SER A 497
LEU A 751
LEU A 759
ASP A 760
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
None
CYZ  A1302 (-3.8A)
 0.73A 3tkdB-5weoA:
24.5		 3tkdB-5weoA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_B_CYZB267_2
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 9 LYS A 493
MET A 496
SER A 497
LEU A 751
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
None
CYZ  A1302 (-2.9A)
 0.90A 3tkdB-5weoA:
24.5		 3tkdB-5weoA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_B_CYZB267_2
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LYS A 493
PRO A 494
MET A 496
LEU A 751
SER A 754
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
None
CYZ  A1302 ( 4.1A)
 0.90A 3tkdB-5weoA:
24.5		 3tkdB-5weoA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_B_CYZB267_2
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
 0.66A 3tkdB-5weoA:
24.5		 3tkdB-5weoA:
33.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_1
(POL POLYPROTEIN)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LEU A 363
GLY A 239
ALA A 240
ILE A 209
VAL A 242
 None
 0.77A 3u7sA-5weoA:
undetectable		 3u7sA-5weoA:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_C_QMRC1214_1
(CAPITELLA TELETA
ACHBP)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		4 / 8 VAL A1154
CYH A 528
ILE A1150
ILE A1152
 None
 0.80A 4afgD-5weoA:
undetectable
4afgE-5weoA:
undetectable		 4afgD-5weoA:
12.23
4afgE-5weoA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_2
(ASPARTYL PROTEASE)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 10 LEU A1195
GLY A1015
ALA A1016
ILE A1187
VAL A1194
 None
 0.87A 4dqbB-5weoA:
undetectable		 4dqbB-5weoA:
8.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_2
(ASPARTYL PROTEASE)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 10 LEU A1195
GLY A1015
ALA A1016
ILE A1187
VAL A1194
 None
 0.82A 4dqeB-5weoA:
undetectable		 4dqeB-5weoA:
8.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_2
(WILD-TYPE HIV-1
PROTEASE DIMER)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 10 LEU A1195
GLY A1015
ALA A1016
ILE A1187
VAL A1194
 None
 0.87A 4dqhB-5weoA:
undetectable		 4dqhB-5weoA:
8.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA504_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		4 / 8 PHE A 245
LEU A 124
ILE A 125
ILE A 193
 None
 0.80A 4em2A-5weoA:
undetectable		 4em2A-5weoA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMA_D_ADND604_1
(PYRUVATE KINASE)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		3 / 3 ARG A 300
GLU A  40
ASN A  10
 None
 0.72A 4imaD-5weoA:
2.5		 4imaD-5weoA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IP7_D_ADND604_1
(PYRUVATE KINASE
ISOZYMES L)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		3 / 3 ARG A 300
GLU A  40
ASN A  10
 None
 0.67A 4ip7D-5weoA:
undetectable		 4ip7D-5weoA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		4 / 7 VAL A 291
MET A 292
ALA A 295
PHE A 296
 None
 1.00A 4lb2A-5weoA:
undetectable		 4lb2A-5weoA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_B_DM5B602_1
(SERUM ALBUMIN)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 VAL A 291
MET A 292
ALA A 295
PHE A 296
TYR A  71
 None
 1.43A 4lb2B-5weoA:
2.4		 4lb2B-5weoA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_A_8PRA603_1
(TRANSPORTER)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 VAL A 530
ALA A 532
TYR A 533
SER A 537
GLY A 535
 None
 1.31A 4mm4A-5weoA:
undetectable		 4mm4A-5weoA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 VAL A 530
ALA A 532
TYR A 533
SER A 537
GLY A 535
 None
 1.25A 4mm5A-5weoA:
undetectable		 4mm5A-5weoA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 11 VAL A 530
ALA A 532
TYR A 533
SER A 537
GLY A 535
 None
 1.21A 4mmaA-5weoA:
2.7		 4mmaA-5weoA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 VAL A 530
ALA A 532
TYR A 533
SER A 537
GLY A 535
 None
 1.27A 4mmbA-5weoA:
undetectable		 4mmbA-5weoA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_A_29QA603_1
(TRANSPORTER)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 VAL A 530
ALA A 532
TYR A 533
SER A 537
GLY A 535
 None
 1.21A 4mmeA-5weoA:
undetectable		 4mmeA-5weoA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_B_29QB603_1
(TRANSPORTER)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 VAL A 530
ALA A 532
TYR A 533
SER A 537
GLY A 535
 None
 1.22A 4mmeB-5weoA:
undetectable		 4mmeB-5weoA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 VAL A 530
ALA A 532
TYR A 533
SER A 537
GLY A 535
 None
 1.26A 4mmfA-5weoA:
undetectable		 4mmfA-5weoA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA503_1
(PENTALENIC ACID
SYNTHASE)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		4 / 7 ALA A 223
LEU A 121
LEU A 124
ILE A 222
 None
 0.76A 4ubsA-5weoA:
undetectable		 4ubsA-5weoA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_A_RTZA602_1
(CYTOCHROME P450 2D6)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 PHE A  74
GLY A 340
LEU A 341
VAL A 248
PHE A 258
 None
 1.06A 4wnwA-5weoA:
undetectable		 4wnwA-5weoA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_1
(CYTOCHROME P450 2D6)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 PHE A  74
GLY A 340
LEU A 341
VAL A 248
PHE A 258
 None
 1.06A 4wnwB-5weoA:
0.0		 4wnwB-5weoA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_B_1FLB1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LEU A 650
THR A 686
THR A 685
ILE A 400
LEU A 401
 None
 1.46A 5g48B-5weoA:
undetectable		 5g48B-5weoA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		3 / 3 ALA A 295
ASN A 298
LEU A 299
 None
 0.36A 5i1nB-5weoA:
undetectable		 5i1nB-5weoA:
3.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		3 / 3 ALA A 295
ASN A 298
LEU A 299
 None
 0.39A 5i1pA-5weoA:
undetectable		 5i1pA-5weoA:
3.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L1F_B_6ZPB902_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 SER A 516
ASP A 519
PRO A 520
LEU A 620
SER A 788
 None
 1.48A 5l1fB-5weoA:
52.0		 5l1fB-5weoA:
77.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L1F_B_6ZPB902_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 SER A 516
ASP A 519
PRO A 520
TYR A 616
LEU A 620
 None
 1.11A 5l1fB-5weoA:
52.0		 5l1fB-5weoA:
77.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		4 / 7 SER A 516
ASP A 519
PRO A 520
TYR A 616
 None
 0.79A 5l1fC-5weoA:
51.8		 5l1fC-5weoA:
77.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L1F_D_6ZPD902_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 10 PHE A 517
PRO A 520
TYR A 616
ASN A 619
LEU A 620
 None
 1.04A 5l1fD-5weoA:
51.5		 5l1fD-5weoA:
77.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L1F_D_6ZPD902_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 10 SER A 516
ASP A 519
PRO A 520
TYR A 616
LEU A 620
 None
 1.18A 5l1fD-5weoA:
51.5		 5l1fD-5weoA:
77.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L1F_D_6ZPD902_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 10 SER A 516
PHE A 517
PRO A 520
TYR A 616
LEU A 620
 None
 1.29A 5l1fD-5weoA:
51.5		 5l1fD-5weoA:
77.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		4 / 8 ALA A 288
PHE A 258
LEU A 341
VAL A  31
 None
 0.70A 5nujA-5weoA:
undetectable		 5nujA-5weoA:
6.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		4 / 8 GLY A 142
GLN A 147
LEU A 143
THR A 145
 None
 1.08A 5sxqB-5weoA:
undetectable		 5sxqB-5weoA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		4 / 8 GLY A 142
GLN A 147
LEU A 143
THR A 145
 None
 1.07A 5syjA-5weoA:
2.3		 5syjA-5weoA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_2
(CYTOCHROME P450 2C9)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		4 / 4 PHE A 438
LEU A 467
LEU A 742
VAL A 396
 None
 1.26A 5xxiA-5weoA:
undetectable		 5xxiA-5weoA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		3 / 3 LYS A 506
PRO A 507
LYS A 509
 None
 0.87A 5y9yA-5weoA:
undetectable		 5y9yA-5weoA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_0
(PROTEASE)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 LEU A 363
GLY A 239
ALA A 240
ILE A 209
VAL A 242
 None
 0.69A 6dh0A-5weoA:
undetectable		 6dh0A-5weoA:
6.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DLZ_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		7 / 10 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
ASP A 760
LYS A 763
 CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.35A 6dlzA-5weoA:
56.2
6dlzD-5weoA:
56.0		 6dlzA-5weoA:
100.00
6dlzD-5weoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DLZ_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		7 / 10 MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
ASP A 760
LYS A 763
 CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.45A 6dlzB-5weoA:
55.9
6dlzC-5weoA:
56.1		 6dlzB-5weoA:
100.00
6dlzC-5weoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DLZ_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		7 / 10 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
ASP A 760
LYS A 763
 CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.28A 6dlzB-5weoA:
55.9
6dlzC-5weoA:
56.1		 6dlzB-5weoA:
100.00
6dlzC-5weoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DLZ_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		8 / 11 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
ASP A 760
LYS A 763
 CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.42A 6dlzA-5weoA:
56.2
6dlzD-5weoA:
56.0		 6dlzA-5weoA:
100.00
6dlzD-5weoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM0_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		7 / 9 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
ASP A 760
LYS A 763
 CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.32A 6dm0A-5weoA:
45.4
6dm0D-5weoA:
56.0		 6dm0A-5weoA:
100.00
6dm0D-5weoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM0_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 10 MET A 496
SER A 497
LEU A 751
LEU A 759
ASP A 760
LYS A 763
 CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
None
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.49A 6dm0B-5weoA:
55.9
6dm0C-5weoA:
45.3		 6dm0B-5weoA:
100.00
6dm0C-5weoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM0_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		7 / 9 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
ASP A 760
LYS A 763
 CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.32A 6dm0B-5weoA:
56.0
6dm0C-5weoA:
45.3		 6dm0B-5weoA:
100.00
6dm0C-5weoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM0_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 9 MET A 496
SER A 497
LEU A 751
LEU A 759
ASP A 760
LYS A 763
 CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
None
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.47A 6dm0A-5weoA:
45.4
6dm0D-5weoA:
56.0		 6dm0A-5weoA:
100.00
6dm0D-5weoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM1_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		7 / 10 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
ASP A 760
LYS A 763
 CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.34A 6dm1A-5weoA:
56.1
6dm1D-5weoA:
55.9		 6dm1A-5weoA:
100.00
6dm1D-5weoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM1_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		7 / 10 MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
ASP A 760
LYS A 763
 CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.44A 6dm1B-5weoA:
55.9
6dm1C-5weoA:
56.1		 6dm1B-5weoA:
100.00
6dm1C-5weoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM1_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		7 / 10 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
ASP A 760
LYS A 763
 CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.28A 6dm1B-5weoA:
55.9
6dm1C-5weoA:
56.1		 6dm1B-5weoA:
100.00
6dm1C-5weoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM1_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		8 / 11 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
ASP A 760
LYS A 763
 CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.43A 6dm1A-5weoA:
56.1
6dm1D-5weoA:
55.9		 6dm1A-5weoA:
100.00
6dm1D-5weoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM2_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		7 / 9 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
ASP A 760
LYS A 763
 CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.31A 6dm2A-5weoA:
56.2
6dm2D-5weoA:
56.1		 6dm2A-5weoA:
100.00
6dm2D-5weoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM2_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		7 / 10 MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
ASP A 760
LYS A 763
 CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.47A 6dm2B-5weoA:
56.1
6dm2C-5weoA:
56.2		 6dm2B-5weoA:
100.00
6dm2C-5weoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM2_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		7 / 9 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
ASP A 760
LYS A 763
 CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.24A 6dm2B-5weoA:
56.1
6dm2C-5weoA:
56.2		 6dm2B-5weoA:
100.00
6dm2C-5weoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM2_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		7 / 10 MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
ASP A 760
LYS A 763
 CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.43A 6dm2A-5weoA:
56.2
6dm2D-5weoA:
56.1		 6dm2A-5weoA:
100.00
6dm2D-5weoA:
100.00