SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wf2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_2
(PROTEASE)		 5wf2 UNCHARACTERIZED
PROTEIN
(Equus
caballus) 		3 / 3 ARG A 428
VAL A 386
THR A 404
 None
 0.80A 2nmzA-5wf2A:
undetectable		 2nmzA-5wf2A:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_2
(PROTEASE)		 5wf2 UNCHARACTERIZED
PROTEIN
(Equus
caballus) 		3 / 3 ARG A 428
VAL A 386
THR A 404
 None
 0.76A 3ndtA-5wf2A:
undetectable		 3ndtA-5wf2A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_0
(GLYCINE
N-METHYLTRANSFERASE)		 5wf2 UNCHARACTERIZED
PROTEIN
(Equus
caballus) 		4 / 6 SER A 412
LEU A 408
THR A 424
ARG A 428
 None
 1.41A 3thrB-5wf2A:
undetectable		 3thrB-5wf2A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_B_IBPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5wf2 UNCHARACTERIZED
PROTEIN
(Equus
caballus) 		5 / 10 VAL A 363
GLY A 384
ALA A 385
SER A 388
LEU A 389
 None
 0.92A 4ph9B-5wf2A:
undetectable		 4ph9B-5wf2A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_B_1FLB1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 5wf2 UNCHARACTERIZED
PROTEIN
(Equus
caballus) 		5 / 9 LEU A 364
THR A 404
LEU A 408
ILE A 426
LEU A 427
 None
 1.40A 5g48B-5wf2A:
undetectable		 5g48B-5wf2A:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)		 5wf2 UNCHARACTERIZED
PROTEIN
(Equus
caballus) 		4 / 8 GLN A 379
GLY A 372
GLU A 410
ILE A 368
 None
 0.99A 5vlmD-5wf2A:
3.4		 5vlmD-5wf2A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IE8_A_CHDA201_0
(REGULATORY PROTEIN)		 5wf2 UNCHARACTERIZED
PROTEIN
(Equus
caballus) 		5 / 12 LEU A 364
ALA A 382
CYH A 434
LEU A 427
LEU A 371
 None
 1.12A 6ie8A-5wf2A:
undetectable		 6ie8A-5wf2A:
20.20