SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wft'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NH8_A_HISA289_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 5wft PELB
(Pseudomonas
aeruginosa) 		4 / 5 ASP A 369
LEU A 377
ALA A 360
LEU A 341
 None
 1.13A 1nh8A-5wftA:
undetectable		 1nh8A-5wftA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_2
(TRANSPORTER)		 5wft PELB
(Pseudomonas
aeruginosa) 		3 / 3 SER A 364
MET A 367
ASP A 326
 None
 0.83A 4mm4B-5wftA:
undetectable		 4mm4B-5wftA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2O_B_CLQB1079_0
(SAPOSIN-B)		 5wft PELB
(Pseudomonas
aeruginosa) 		3 / 3 MET A 386
GLU A 390
LEU A 394
 None
 0.48A 4v2oB-5wftA:
undetectable		 4v2oB-5wftA:
21.88