SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wgc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DMA_B_NCAB700_0 (EXOTOXIN A)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	4 / 6	HIS A 91 GLY A 90 ALA A 57 GLU A 58	None	1.00A	1dmaB-5wgcA: undetectable	1dmaB-5wgcA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DZ8_B_CAMB502_0 (CYTOCHROME P450-CAM)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 9	THR A 295 LEU A 20 VAL A 18 GLY A 169 ASP A 302	None	1.26A	1dz8B-5wgcA: undetectable	1dz8B-5wgcA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DZ8_B_CAMB502_0 (CYTOCHROME P450-CAM)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 9	THR A 295 LEU A 20 VAL A 18 GLY A 169 THR A 145	None	1.11A	1dz8B-5wgcA: undetectable	1dz8B-5wgcA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DZ9_B_CAMB502_0 (CYTOCHROME P450-CAM)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 9	THR A 295 LEU A 20 VAL A 18 GLY A 169 ASP A 302	None	1.25A	1dz9B-5wgcA: undetectable	1dz9B-5wgcA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DZ9_B_CAMB502_0 (CYTOCHROME P450-CAM)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 9	THR A 295 LEU A 20 VAL A 18 GLY A 169 THR A 145	None	1.08A	1dz9B-5wgcA: undetectable	1dz9B-5wgcA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EIZ_A_SAMA301_0 (FTSJ)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 12	ALA A 84 GLY A 169 GLY A 299 GLY A 300 LEU A 62	None None None 42Y A 118 ( 3.2A) None	0.99A	1eizA-5wgcA: undetectable	1eizA-5wgcA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EJ0_A_SAMA301_0 (FTSJ)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 12	ALA A 84 GLY A 169 GLY A 299 GLY A 300 LEU A 62	None None None 42Y A 118 ( 3.2A) None	0.99A	1ej0A-5wgcA: undetectable	1ej0A-5wgcA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MZ9_A_VDYA1002_4 (CARTILAGE OLIGOMERIC MATRIX PROTEIN)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	4 / 5	LEU A 183 VAL A 13 ALA A 67 CYH A 16	None	1.17A	1mz9D-5wgcA: undetectable	1mz9D-5wgcA: 21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UAK_A_SAMA301_0 (TRNA (GUANINE-N(1)-)-METH YLTRANSFERASE)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	6 / 12	LEU A 86 SER A 85 GLY A 120 LEU A 298 GLY A 301 GLY A 300	42Y A 118 ( 4.7A) None 42Y A 118 ( 4.9A) None None 42Y A 118 ( 3.2A)	1.29A	1uakA-5wgcA: undetectable	1uakA-5wgcA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UAK_A_SAMA301_0 (TRNA (GUANINE-N(1)-)-METH YLTRANSFERASE)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	6 / 12	SER A 85 GLN A 89 GLY A 120 LEU A 298 GLY A 301 GLY A 300	None None 42Y A 118 ( 4.9A) None None 42Y A 118 ( 3.2A)	1.34A	1uakA-5wgcA: undetectable	1uakA-5wgcA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UAK_A_SAMA301_0 (TRNA (GUANINE-N(1)-)-METH YLTRANSFERASE)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	6 / 12	SER A 85 GLN A 89 GLY A 121 LEU A 298 GLY A 301 GLY A 300	None None None None None 42Y A 118 ( 3.2A)	1.23A	1uakA-5wgcA: undetectable	1uakA-5wgcA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AOH_C_FRDC305_1 (POL POLYPROTEIN PEPTIDE INHIBITOR)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	4 / 5	LEU A 298 ASP A 302 GLY A 268 ALA A 166	None	0.97A	2aohA-5wgcA: undetectable	2aohA-5wgcA: 17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J9D_A_ACTA1117_0 (HYPOTHETICAL NITROGEN REGULATORY PII-LIKE PROTEIN MJ0059)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	3 / 3	ASP A 137 ARG A 176 ARG A 138	None	1.06A	2j9dA-5wgcA: undetectable 2j9dC-5wgcA: undetectable	2j9dA-5wgcA: undetectable 2j9dC-5wgcA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7P_A_SALA1001_1 (LYSR-TYPE REGULATORY PROTEIN)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	4 / 6	SER A 42 ARG A 270 PRO A 161 GLY A 162	None	1.05A	2y7pA-5wgcA: undetectable	2y7pA-5wgcA: 16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ME6_A_CGEA501_1 (CYTOCHROME P450 2B4)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 10	PHE A 277 ILE A 282 ALA A 275 VAL A 325 VAL A 262	None None AFY A 401 (-3.6A) None None	0.92A	3me6A-5wgcA: undetectable	3me6A-5wgcA: 11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ME6_B_CGEB501_1 (CYTOCHROME P450 2B4)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	4 / 8	PHE A 277 ILE A 282 ALA A 275 VAL A 325	None None AFY A 401 (-3.6A) None	0.70A	3me6B-5wgcA: undetectable	3me6B-5wgcA: 11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ME6_C_CGEC501_1 (CYTOCHROME P450 2B4)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 9	PHE A 277 ILE A 282 ALA A 275 VAL A 325 VAL A 262	None None AFY A 401 (-3.6A) None None	0.92A	3me6C-5wgcA: undetectable	3me6C-5wgcA: 11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ME6_D_CGED501_1 (CYTOCHROME P450 2B4)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 9	PHE A 277 ILE A 282 ALA A 275 VAL A 325 VAL A 262	None None AFY A 401 (-3.6A) None None	0.97A	3me6D-5wgcA: undetectable	3me6D-5wgcA: 11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OKX_B_SAMB201_1 (YAEB-LIKE PROTEIN RPA0152)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 12	LEU A 30 LEU A 39 ARG A 37 GLY A 162 THR A 163	None None None None AFY A 401 (-3.4A)	1.17A	3okxB-5wgcA: undetectable	3okxB-5wgcA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3THR_D_C2FD1200_0 (GLYCINE N-METHYLTRANSFERASE)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 12	MET A 59 SER A 47 LEU A 298 HIS A 266 ARG A 156	None	1.25A	3thrA-5wgcA: undetectable 3thrB-5wgcA: undetectable 3thrC-5wgcA: undetectable 3thrD-5wgcA: undetectable	3thrA-5wgcA: undetectable 3thrB-5wgcA: undetectable 3thrC-5wgcA: undetectable 3thrD-5wgcA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HTF_A_SAMA301_0 (S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 12	GLY A 268 LEU A 264 ALA A 275 GLN A 241 VAL A 327	None None AFY A 401 (-3.6A) None AFY A 401 ( 4.6A)	0.97A	4htfA-5wgcA: undetectable	4htfA-5wgcA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HTF_B_SAMB301_0 (S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 12	GLY A 268 LEU A 264 ALA A 275 GLN A 241 VAL A 327	None None AFY A 401 (-3.6A) None AFY A 401 ( 4.6A)	0.97A	4htfB-5wgcA: undetectable	4htfB-5wgcA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IAQ_A_2GMA2001_1 (CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 1B AND E. COLI SOLUBLE CYTOCHROME B562)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 12	ASP A 302 ALA A 49 PHE A 291 LEU A 316 THR A 288	None	1.29A	4iaqA-5wgcA: undetectable	4iaqA-5wgcA: 11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IAR_A_ERMA2001_1 (CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 1B AND E. COLI SOLUBLE CYTOCHROME B562)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 12	ASP A 302 ALA A 49 PHE A 291 LEU A 316 THR A 288	None	1.35A	4iarA-5wgcA: undetectable	4iarA-5wgcA: 11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOE_H_TR6H101_1 (DNA TOPOISOMERASE 4 SUBUNIT A DNA TOPOISOMERASE 4 SUBUNIT B E-SITE DNA4)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	4 / 7	SER A 326 GLY A 146 ASP A 147 GLU A 113	42Y A 118 ( 3.7A) None None None	0.76A	4koeA-5wgcA: undetectable 4koeB-5wgcA: undetectable 4koeD-5wgcA: undetectable	4koeA-5wgcA: 10.08 4koeB-5wgcA: 10.08 4koeD-5wgcA: 13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVL_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 11	ALA A 140 ALA A 141 GLY A 178 GLY A 179 ALA A 14	None	0.99A	4qvlK-5wgcA: undetectable 4qvlL-5wgcA: undetectable	4qvlK-5wgcA: 20.51 4qvlL-5wgcA: 15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVL_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 11	ALA A 140 ALA A 141 GLY A 178 GLY A 179 ALA A 14	None	0.99A	4qvlY-5wgcA: undetectable 4qvlZ-5wgcA: undetectable	4qvlY-5wgcA: 20.51 4qvlZ-5wgcA: 15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVM_B_BO2B201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 11	HIS A 309 THR A 295 GLY A 301 ALA A 305 THR A 170	None	1.12A	4qvmV-5wgcA: undetectable 4qvmb-5wgcA: undetectable	4qvmV-5wgcA: 17.61 4qvmb-5wgcA: 17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVM_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 9	ALA A 140 ALA A 141 GLY A 178 GLY A 179 ALA A 14	None	1.00A	4qvmK-5wgcA: undetectable 4qvmL-5wgcA: undetectable	4qvmK-5wgcA: 20.51 4qvmL-5wgcA: 15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVM_N_BO2N201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 11	HIS A 309 THR A 295 GLY A 301 ALA A 305 THR A 170	None	1.12A	4qvmH-5wgcA: undetectable 4qvmN-5wgcA: undetectable	4qvmH-5wgcA: 17.61 4qvmN-5wgcA: 17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVM_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 10	ALA A 140 ALA A 141 GLY A 178 GLY A 179 ALA A 14	None	0.99A	4qvmY-5wgcA: undetectable 4qvmZ-5wgcA: undetectable	4qvmY-5wgcA: 20.51 4qvmZ-5wgcA: 15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVN_B_BO2B201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 12	HIS A 309 THR A 295 GLY A 301 ALA A 305 THR A 170	None	1.17A	4qvnV-5wgcA: undetectable 4qvnb-5wgcA: undetectable	4qvnV-5wgcA: 17.61 4qvnb-5wgcA: 17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVN_N_BO2N201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 12	HIS A 309 THR A 295 GLY A 301 ALA A 305 THR A 170	None	1.17A	4qvnH-5wgcA: undetectable 4qvnN-5wgcA: undetectable	4qvnH-5wgcA: 17.61 4qvnN-5wgcA: 17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVP_B_BO2B201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 11	HIS A 309 THR A 295 GLY A 301 ALA A 305 THR A 170	None	1.16A	4qvpV-5wgcA: undetectable 4qvpb-5wgcA: undetectable	4qvpV-5wgcA: 17.61 4qvpb-5wgcA: 17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVP_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 10	ALA A 140 ALA A 141 GLY A 178 GLY A 179 ALA A 14	None	1.00A	4qvpK-5wgcA: undetectable 4qvpL-5wgcA: undetectable	4qvpK-5wgcA: 20.51 4qvpL-5wgcA: 15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVP_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 10	ALA A 140 ALA A 141 GLY A 178 GLY A 179 ALA A 14	None	1.00A	4qvpY-5wgcA: undetectable 4qvpZ-5wgcA: undetectable	4qvpY-5wgcA: 20.51 4qvpZ-5wgcA: 15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVQ_B_BO2B201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 11	HIS A 309 THR A 295 GLY A 301 ALA A 305 THR A 170	None	1.15A	4qvqV-5wgcA: undetectable 4qvqb-5wgcA: undetectable	4qvqV-5wgcA: 17.61 4qvqb-5wgcA: 17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVQ_N_BO2N201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 11	HIS A 309 THR A 295 GLY A 301 ALA A 305 THR A 170	None	1.15A	4qvqH-5wgcA: undetectable 4qvqN-5wgcA: undetectable	4qvqH-5wgcA: 17.61 4qvqN-5wgcA: 17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QW1_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 11	ALA A 140 ALA A 141 GLY A 178 GLY A 179 ALA A 14	None	1.00A	4qw1K-5wgcA: undetectable 4qw1L-5wgcA: undetectable	4qw1K-5wgcA: 20.51 4qw1L-5wgcA: 15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QW1_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 10	ALA A 140 ALA A 141 GLY A 178 GLY A 179 ALA A 14	None	1.00A	4qw1Y-5wgcA: undetectable 4qw1Z-5wgcA: undetectable	4qw1Y-5wgcA: 20.51 4qw1Z-5wgcA: 15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QW3_B_BO2B201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 11	HIS A 309 THR A 295 GLY A 301 ALA A 305 THR A 170	None	1.12A	4qw3V-5wgcA: undetectable 4qw3b-5wgcA: undetectable	4qw3V-5wgcA: 17.61 4qw3b-5wgcA: 17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QW3_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 10	ALA A 140 ALA A 141 GLY A 178 GLY A 179 ALA A 14	None	0.98A	4qw3K-5wgcA: undetectable 4qw3L-5wgcA: undetectable	4qw3K-5wgcA: 20.51 4qw3L-5wgcA: 15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QW3_N_BO2N201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 11	HIS A 309 THR A 295 GLY A 301 ALA A 305 THR A 170	None	1.12A	4qw3H-5wgcA: undetectable 4qw3N-5wgcA: undetectable	4qw3H-5wgcA: 17.61 4qw3N-5wgcA: 17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QW3_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 10	ALA A 140 ALA A 141 GLY A 178 GLY A 179 ALA A 14	None	0.98A	4qw3Y-5wgcA: undetectable 4qw3Z-5wgcA: undetectable	4qw3Y-5wgcA: 20.51 4qw3Z-5wgcA: 15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UBE_A_2FAA401_2 (ADENOSINE KINASE)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	4 / 4	ALA A 67 VAL A 18 GLY A 301 THR A 145	None	1.13A	4ubeA-5wgcA: undetectable	4ubeA-5wgcA: 12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YJI_A_TYLA502_1 (ARYL ACYLAMIDASE)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	4 / 7	SER A 326 GLY A 120 GLY A 121 ILE A 304	42Y A 118 ( 3.7A) 42Y A 118 ( 4.9A) None None	0.73A	4yjiA-5wgcA: undetectable	4yjiA-5wgcA: 11.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z53_H_TR6H101_1 (DNA TOPOISOMERASE 4 SUBUNIT B,DNA TOPOISOMERASE 4 SUBUNIT A E-SITE DNA)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	4 / 7	GLY A 146 ASP A 147 GLU A 113 SER A 326	None None None 42Y A 118 ( 3.7A)	0.74A	4z53A-5wgcA: undetectable 4z53B-5wgcA: undetectable	4z53A-5wgcA: 7.21 4z53B-5wgcA: 7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BXN_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 11	ALA A 140 ALA A 141 GLY A 178 GLY A 179 ALA A 14	None	0.97A	5bxnK-5wgcA: undetectable 5bxnL-5wgcA: undetectable	5bxnK-5wgcA: 20.51 5bxnL-5wgcA: 15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BXN_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 11	ALA A 140 ALA A 141 GLY A 178 GLY A 179 ALA A 14	None	0.98A	5bxnY-5wgcA: undetectable 5bxnZ-5wgcA: undetectable	5bxnY-5wgcA: 20.51 5bxnZ-5wgcA: 15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IGI_A_ZITA402_1 (MACROLIDE 2'-PHOSPHOTRANSFERAS E)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 12	ASP A 302 VAL A 164 ALA A 166 GLY A 146 THR A 145	None	1.12A	5igiA-5wgcA: undetectable	5igiA-5wgcA: 15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IGJ_A_CTYA402_1 (MACROLIDE 2'-PHOSPHOTRANSFERAS E)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	6 / 12	ASP A 302 VAL A 164 ALA A 166 MET A 149 GLY A 146 THR A 145	None	1.33A	5igjA-5wgcA: undetectable	5igjA-5wgcA: 15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JI0_A_9CRA501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 11	ILE A 259 LEU A 324 LEU A 249 ALA A 248 LEU A 316	None	1.19A	5ji0A-5wgcA: undetectable	5ji0A-5wgcA: 17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L5Z_B_BO2B201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 12	HIS A 309 THR A 295 GLY A 301 ALA A 305 THR A 170	None	1.13A	5l5zV-5wgcA: undetectable 5l5zb-5wgcA: undetectable	5l5zV-5wgcA: 17.61 5l5zb-5wgcA: 17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L5Z_N_BO2N201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 12	HIS A 309 THR A 295 GLY A 301 ALA A 305 THR A 170	None	1.14A	5l5zH-5wgcA: undetectable 5l5zN-5wgcA: undetectable	5l5zH-5wgcA: 17.61 5l5zN-5wgcA: 17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L66_B_BO2B201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 11	HIS A 309 THR A 295 GLY A 301 ALA A 305 THR A 170	None	1.15A	5l66V-5wgcA: undetectable 5l66b-5wgcA: undetectable	5l66V-5wgcA: 17.61 5l66b-5wgcA: 17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5W5V_A_ANWA701_0 (SERINE/THREONINE-PRO TEIN KINASE TBK1)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 9	LEU A 298 ALA A 305 VAL A 263 THR A 163 THR A 288	None None None AFY A 401 (-3.4A) None	1.42A	5w5vA-5wgcA: undetectable	5w5vA-5wgcA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XXI_A_LSNA501_1 (CYTOCHROME P450 2C9)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 12	ALA A 104 VAL A 73 GLY A 15 ALA A 14 LEU A 132	None	0.99A	5xxiA-5wgcA: undetectable	5xxiA-5wgcA: 9.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CDU_B_EY4B500_0 (CHIMERIC ALPHA1GABAA RECEPTOR)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	4 / 6	GLN A 101 VAL A 100 ALA A 60 THR A 145	None	1.00A	6cduB-5wgcA: undetectable 6cduC-5wgcA: undetectable	6cduB-5wgcA: undetectable 6cduC-5wgcA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6IFT_A_SAMA301_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE A)	5wgc	DAUNORUBICIN-DOXORUB ICIN POLYKETIDE SYNTHASE (Streptomyces peucetius)	5 / 12	ILE A 304 GLY A 301 GLY A 299 ALA A 166 LEU A 86	None None None None 42Y A 118 ( 4.7A)	0.97A	6iftA-5wgcA: undetectable	6iftA-5wgcA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DMA_B_NCAB700_0","EXOTOXIN A","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",4,"HIS A  91;GLY A  90;ALA A  57;GLU A  58","None","1.00A","1dmaB-5wgcA:undetectable","1dmaB-5wgcA:undetectable"],["1DZ8_B_CAMB502_0","CYTOCHROME P450-CAM","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"THR A 295;LEU A  20;VAL A  18;GLY A 169;ASP A 302","None","1.26A","1dz8B-5wgcA:undetectable","1dz8B-5wgcA:undetectable"],["1DZ8_B_CAMB502_0","CYTOCHROME P450-CAM","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"THR A 295;LEU A  20;VAL A  18;GLY A 169;THR A 145","None","1.11A","1dz8B-5wgcA:undetectable","1dz8B-5wgcA:undetectable"],["1DZ9_B_CAMB502_0","CYTOCHROME P450-CAM","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"THR A 295;LEU A  20;VAL A  18;GLY A 169;ASP A 302","None","1.25A","1dz9B-5wgcA:undetectable","1dz9B-5wgcA:undetectable"],["1DZ9_B_CAMB502_0","CYTOCHROME P450-CAM","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"THR A 295;LEU A  20;VAL A  18;GLY A 169;THR A 145","None","1.08A","1dz9B-5wgcA:undetectable","1dz9B-5wgcA:undetectable"],["1EIZ_A_SAMA301_0","FTSJ","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"ALA A  84;GLY A 169;GLY A 299;GLY A 300;LEU A  62","None;None;None;42Y A 118 ( 3.2A);None","0.99A","1eizA-5wgcA:undetectable","1eizA-5wgcA:undetectable"],["1EJ0_A_SAMA301_0","FTSJ","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"ALA A  84;GLY A 169;GLY A 299;GLY A 300;LEU A  62","None;None;None;42Y A 118 ( 3.2A);None","0.99A","1ej0A-5wgcA:undetectable","1ej0A-5wgcA:undetectable"],["1MZ9_A_VDYA1002_4","CARTILAGE OLIGOMERIC MATRIX PROTEIN;CARTILAGE OLIGOMERIC MATRIX PROTEIN","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",4,"LEU A 183;VAL A  13;ALA A  67;CYH A  16","None","1.17A","1mz9D-5wgcA:undetectable","1mz9D-5wgcA:21.79"],["1UAK_A_SAMA301_0","TRNA (GUANINE-N(1)-)-METHYLTRANSFERASE","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",6,"LEU A  86;SER A  85;GLY A 120;LEU A 298;GLY A 301;GLY A 300","42Y A 118 ( 4.7A);None;42Y A 118 ( 4.9A);None;None;42Y A 118 ( 3.2A)","1.29A","1uakA-5wgcA:undetectable","1uakA-5wgcA:undetectable"],["1UAK_A_SAMA301_0","TRNA (GUANINE-N(1)-)-METHYLTRANSFERASE","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",6,"SER A  85;GLN A  89;GLY A 120;LEU A 298;GLY A 301;GLY A 300","None;None;42Y A 118 ( 4.9A);None;None;42Y A 118 ( 3.2A)","1.34A","1uakA-5wgcA:undetectable","1uakA-5wgcA:undetectable"],["1UAK_A_SAMA301_0","TRNA (GUANINE-N(1)-)-METHYLTRANSFERASE","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",6,"SER A  85;GLN A  89;GLY A 121;LEU A 298;GLY A 301;GLY A 300","None;None;None;None;None;42Y A 118 ( 3.2A)","1.23A","1uakA-5wgcA:undetectable","1uakA-5wgcA:undetectable"],["2AOH_C_FRDC305_1","POL POLYPROTEIN;PEPTIDE INHIBITOR","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",4,"LEU A 298;ASP A 302;GLY A 268;ALA A 166","None","0.97A","2aohA-5wgcA:undetectable","2aohA-5wgcA:17.65"],["2J9D_A_ACTA1117_0","HYPOTHETICAL NITROGEN REGULATORY PII-LIKE PROTEIN MJ0059","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",3,"ASP A 137;ARG A 176;ARG A 138","None","1.06A","2j9dA-5wgcA:undetectable;2j9dC-5wgcA:undetectable","2j9dA-5wgcA:undetectable;2j9dC-5wgcA:undetectable"],["2Y7P_A_SALA1001_1","LYSR-TYPE REGULATORY PROTEIN","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",4,"SER A  42;ARG A 270;PRO A 161;GLY A 162","None","1.05A","2y7pA-5wgcA:undetectable","2y7pA-5wgcA:16.42"],["3ME6_A_CGEA501_1","CYTOCHROME P450 2B4","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"PHE A 277;ILE A 282;ALA A 275;VAL A 325;VAL A 262","None;None;AFY A 401 (-3.6A);None;None","0.92A","3me6A-5wgcA:undetectable","3me6A-5wgcA:11.29"],["3ME6_B_CGEB501_1","CYTOCHROME P450 2B4","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",4,"PHE A 277;ILE A 282;ALA A 275;VAL A 325","None;None;AFY A 401 (-3.6A);None","0.70A","3me6B-5wgcA:undetectable","3me6B-5wgcA:11.29"],["3ME6_C_CGEC501_1","CYTOCHROME P450 2B4","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"PHE A 277;ILE A 282;ALA A 275;VAL A 325;VAL A 262","None;None;AFY A 401 (-3.6A);None;None","0.92A","3me6C-5wgcA:undetectable","3me6C-5wgcA:11.29"],["3ME6_D_CGED501_1","CYTOCHROME P450 2B4","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"PHE A 277;ILE A 282;ALA A 275;VAL A 325;VAL A 262","None;None;AFY A 401 (-3.6A);None;None","0.97A","3me6D-5wgcA:undetectable","3me6D-5wgcA:11.29"],["3OKX_B_SAMB201_1","YAEB-LIKE PROTEIN RPA0152","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"LEU A  30;LEU A  39;ARG A  37;GLY A 162;THR A 163","None;None;None;None;AFY A 401 (-3.4A)","1.17A","3okxB-5wgcA:undetectable","3okxB-5wgcA:undetectable"],["3THR_D_C2FD1200_0","GLYCINE N-METHYLTRANSFERASE","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"MET A  59;SER A  47;LEU A 298;HIS A 266;ARG A 156","None","1.25A","3thrA-5wgcA:undetectable;3thrB-5wgcA:undetectable;3thrC-5wgcA:undetectable;3thrD-5wgcA:undetectable","3thrA-5wgcA:undetectable;3thrB-5wgcA:undetectable;3thrC-5wgcA:undetectable;3thrD-5wgcA:undetectable"],["4HTF_A_SAMA301_0","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"GLY A 268;LEU A 264;ALA A 275;GLN A 241;VAL A 327","None;None;AFY A 401 (-3.6A);None;AFY A 401 ( 4.6A)","0.97A","4htfA-5wgcA:undetectable","4htfA-5wgcA:undetectable"],["4HTF_B_SAMB301_0","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"GLY A 268;LEU A 264;ALA A 275;GLN A 241;VAL A 327","None;None;AFY A 401 (-3.6A);None;AFY A 401 ( 4.6A)","0.97A","4htfB-5wgcA:undetectable","4htfB-5wgcA:undetectable"],["4IAQ_A_2GMA2001_1","CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 1B AND E. COLI SOLUBLE CYTOCHROME B562","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"ASP A 302;ALA A  49;PHE A 291;LEU A 316;THR A 288","None","1.29A","4iaqA-5wgcA:undetectable","4iaqA-5wgcA:11.67"],["4IAR_A_ERMA2001_1","CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 1B AND E. COLI SOLUBLE CYTOCHROME B562","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"ASP A 302;ALA A  49;PHE A 291;LEU A 316;THR A 288","None","1.35A","4iarA-5wgcA:undetectable","4iarA-5wgcA:11.73"],["4KOE_H_TR6H101_1","DNA TOPOISOMERASE 4 SUBUNIT A;DNA TOPOISOMERASE 4 SUBUNIT A;DNA TOPOISOMERASE 4 SUBUNIT B;E-SITE DNA4","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",4,"SER A 326;GLY A 146;ASP A 147;GLU A 113","42Y A 118 ( 3.7A);None;None;None","0.76A","4koeA-5wgcA:undetectable;4koeB-5wgcA:undetectable;4koeD-5wgcA:undetectable","4koeA-5wgcA:10.08;4koeB-5wgcA:10.08;4koeD-5wgcA:13.86"],["4QVL_K_BO2K301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"ALA A 140;ALA A 141;GLY A 178;GLY A 179;ALA A  14","None","0.99A","4qvlK-5wgcA:undetectable;4qvlL-5wgcA:undetectable","4qvlK-5wgcA:20.51;4qvlL-5wgcA:15.61"],["4QVL_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"ALA A 140;ALA A 141;GLY A 178;GLY A 179;ALA A  14","None","0.99A","4qvlY-5wgcA:undetectable;4qvlZ-5wgcA:undetectable","4qvlY-5wgcA:20.51;4qvlZ-5wgcA:15.61"],["4QVM_B_BO2B201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"HIS A 309;THR A 295;GLY A 301;ALA A 305;THR A 170","None","1.12A","4qvmV-5wgcA:undetectable;4qvmb-5wgcA:undetectable","4qvmV-5wgcA:17.61;4qvmb-5wgcA:17.19"],["4QVM_K_BO2K301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"ALA A 140;ALA A 141;GLY A 178;GLY A 179;ALA A  14","None","1.00A","4qvmK-5wgcA:undetectable;4qvmL-5wgcA:undetectable","4qvmK-5wgcA:20.51;4qvmL-5wgcA:15.61"],["4QVM_N_BO2N201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"HIS A 309;THR A 295;GLY A 301;ALA A 305;THR A 170","None","1.12A","4qvmH-5wgcA:undetectable;4qvmN-5wgcA:undetectable","4qvmH-5wgcA:17.61;4qvmN-5wgcA:17.19"],["4QVM_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"ALA A 140;ALA A 141;GLY A 178;GLY A 179;ALA A  14","None","0.99A","4qvmY-5wgcA:undetectable;4qvmZ-5wgcA:undetectable","4qvmY-5wgcA:20.51;4qvmZ-5wgcA:15.61"],["4QVN_B_BO2B201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"HIS A 309;THR A 295;GLY A 301;ALA A 305;THR A 170","None","1.17A","4qvnV-5wgcA:undetectable;4qvnb-5wgcA:undetectable","4qvnV-5wgcA:17.61;4qvnb-5wgcA:17.19"],["4QVN_N_BO2N201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"HIS A 309;THR A 295;GLY A 301;ALA A 305;THR A 170","None","1.17A","4qvnH-5wgcA:undetectable;4qvnN-5wgcA:undetectable","4qvnH-5wgcA:17.61;4qvnN-5wgcA:17.19"],["4QVP_B_BO2B201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"HIS A 309;THR A 295;GLY A 301;ALA A 305;THR A 170","None","1.16A","4qvpV-5wgcA:undetectable;4qvpb-5wgcA:undetectable","4qvpV-5wgcA:17.61;4qvpb-5wgcA:17.19"],["4QVP_K_BO2K301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"ALA A 140;ALA A 141;GLY A 178;GLY A 179;ALA A  14","None","1.00A","4qvpK-5wgcA:undetectable;4qvpL-5wgcA:undetectable","4qvpK-5wgcA:20.51;4qvpL-5wgcA:15.61"],["4QVP_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"ALA A 140;ALA A 141;GLY A 178;GLY A 179;ALA A  14","None","1.00A","4qvpY-5wgcA:undetectable;4qvpZ-5wgcA:undetectable","4qvpY-5wgcA:20.51;4qvpZ-5wgcA:15.61"],["4QVQ_B_BO2B201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"HIS A 309;THR A 295;GLY A 301;ALA A 305;THR A 170","None","1.15A","4qvqV-5wgcA:undetectable;4qvqb-5wgcA:undetectable","4qvqV-5wgcA:17.61;4qvqb-5wgcA:17.19"],["4QVQ_N_BO2N201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"HIS A 309;THR A 295;GLY A 301;ALA A 305;THR A 170","None","1.15A","4qvqH-5wgcA:undetectable;4qvqN-5wgcA:undetectable","4qvqH-5wgcA:17.61;4qvqN-5wgcA:17.19"],["4QW1_K_BO2K301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"ALA A 140;ALA A 141;GLY A 178;GLY A 179;ALA A  14","None","1.00A","4qw1K-5wgcA:undetectable;4qw1L-5wgcA:undetectable","4qw1K-5wgcA:20.51;4qw1L-5wgcA:15.61"],["4QW1_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"ALA A 140;ALA A 141;GLY A 178;GLY A 179;ALA A  14","None","1.00A","4qw1Y-5wgcA:undetectable;4qw1Z-5wgcA:undetectable","4qw1Y-5wgcA:20.51;4qw1Z-5wgcA:15.61"],["4QW3_B_BO2B201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"HIS A 309;THR A 295;GLY A 301;ALA A 305;THR A 170","None","1.12A","4qw3V-5wgcA:undetectable;4qw3b-5wgcA:undetectable","4qw3V-5wgcA:17.61;4qw3b-5wgcA:17.19"],["4QW3_K_BO2K301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"ALA A 140;ALA A 141;GLY A 178;GLY A 179;ALA A  14","None","0.98A","4qw3K-5wgcA:undetectable;4qw3L-5wgcA:undetectable","4qw3K-5wgcA:20.51;4qw3L-5wgcA:15.61"],["4QW3_N_BO2N201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"HIS A 309;THR A 295;GLY A 301;ALA A 305;THR A 170","None","1.12A","4qw3H-5wgcA:undetectable;4qw3N-5wgcA:undetectable","4qw3H-5wgcA:17.61;4qw3N-5wgcA:17.19"],["4QW3_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"ALA A 140;ALA A 141;GLY A 178;GLY A 179;ALA A  14","None","0.98A","4qw3Y-5wgcA:undetectable;4qw3Z-5wgcA:undetectable","4qw3Y-5wgcA:20.51;4qw3Z-5wgcA:15.61"],["4UBE_A_2FAA401_2","ADENOSINE KINASE","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",4,"ALA A  67;VAL A  18;GLY A 301;THR A 145","None","1.13A","4ubeA-5wgcA:undetectable","4ubeA-5wgcA:12.96"],["4YJI_A_TYLA502_1","ARYL ACYLAMIDASE","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",4,"SER A 326;GLY A 120;GLY A 121;ILE A 304","42Y A 118 ( 3.7A);42Y A 118 ( 4.9A);None;None","0.73A","4yjiA-5wgcA:undetectable","4yjiA-5wgcA:11.20"],["4Z53_H_TR6H101_1","DNA TOPOISOMERASE 4 SUBUNIT B,DNA TOPOISOMERASE 4 SUBUNIT A;DNA TOPOISOMERASE 4 SUBUNIT B,DNA TOPOISOMERASE 4 SUBUNIT A;E-SITE DNA","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",4,"GLY A 146;ASP A 147;GLU A 113;SER A 326","None;None;None;42Y A 118 ( 3.7A)","0.74A","4z53A-5wgcA:undetectable;4z53B-5wgcA:undetectable","4z53A-5wgcA:7.21;4z53B-5wgcA:7.21"],["5BXN_K_BO2K301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"ALA A 140;ALA A 141;GLY A 178;GLY A 179;ALA A  14","None","0.97A","5bxnK-5wgcA:undetectable;5bxnL-5wgcA:undetectable","5bxnK-5wgcA:20.51;5bxnL-5wgcA:15.61"],["5BXN_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"ALA A 140;ALA A 141;GLY A 178;GLY A 179;ALA A  14","None","0.98A","5bxnY-5wgcA:undetectable;5bxnZ-5wgcA:undetectable","5bxnY-5wgcA:20.51;5bxnZ-5wgcA:15.61"],["5IGI_A_ZITA402_1","MACROLIDE 2'-PHOSPHOTRANSFERASE","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"ASP A 302;VAL A 164;ALA A 166;GLY A 146;THR A 145","None","1.12A","5igiA-5wgcA:undetectable","5igiA-5wgcA:15.23"],["5IGJ_A_CTYA402_1","MACROLIDE 2'-PHOSPHOTRANSFERASE","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",6,"ASP A 302;VAL A 164;ALA A 166;MET A 149;GLY A 146;THR A 145","None","1.33A","5igjA-5wgcA:undetectable","5igjA-5wgcA:15.23"],["5JI0_A_9CRA501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"ILE A 259;LEU A 324;LEU A 249;ALA A 248;LEU A 316","None","1.19A","5ji0A-5wgcA:undetectable","5ji0A-5wgcA:17.84"],["5L5Z_B_BO2B201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"HIS A 309;THR A 295;GLY A 301;ALA A 305;THR A 170","None","1.13A","5l5zV-5wgcA:undetectable;5l5zb-5wgcA:undetectable","5l5zV-5wgcA:17.61;5l5zb-5wgcA:17.19"],["5L5Z_N_BO2N201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"HIS A 309;THR A 295;GLY A 301;ALA A 305;THR A 170","None","1.14A","5l5zH-5wgcA:undetectable;5l5zN-5wgcA:undetectable","5l5zH-5wgcA:17.61;5l5zN-5wgcA:17.19"],["5L66_B_BO2B201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"HIS A 309;THR A 295;GLY A 301;ALA A 305;THR A 170","None","1.15A","5l66V-5wgcA:undetectable;5l66b-5wgcA:undetectable","5l66V-5wgcA:17.61;5l66b-5wgcA:17.19"],["5W5V_A_ANWA701_0","SERINE\/THREONINE-PROTEIN KINASE TBK1","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"LEU A 298;ALA A 305;VAL A 263;THR A 163;THR A 288","None;None;None;AFY A 401 (-3.4A);None","1.42A","5w5vA-5wgcA:undetectable","5w5vA-5wgcA:undetectable"],["5XXI_A_LSNA501_1","CYTOCHROME P450 2C9","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"ALA A 104;VAL A  73;GLY A  15;ALA A  14;LEU A 132","None","0.99A","5xxiA-5wgcA:undetectable","5xxiA-5wgcA:9.84"],["6CDU_B_EY4B500_0","CHIMERIC ALPHA1GABAA RECEPTOR","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",4,"GLN A 101;VAL A 100;ALA A  60;THR A 145","None","1.00A","6cduB-5wgcA:undetectable;6cduC-5wgcA:undetectable","6cduB-5wgcA:undetectable;6cduC-5wgcA:undetectable"],["6IFT_A_SAMA301_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE A","5wgc","DAUNORUBICIN-DOXORUBICIN POLYKETIDE SYNTHASE","Streptomyces peucetius",5,"ILE A 304;GLY A 301;GLY A 299;ALA A 166;LEU A  86","None;None;None;None;42Y A 118 ( 4.7A)","0.97A","6iftA-5wgcA:undetectable","6iftA-5wgcA:undetectable"]]