SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wht'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2O4L_A_TPVA403_1 (PROTEASE)	5wht	PUTATIVE PERTUSSIS-LIKE TOXIN SUBUNIT (Salmonella enterica)	5 / 12	ALA A 89 GLY A 124 VAL A 123 VAL A 68 ILE A 55	None	1.13A	2o4lA-5whtA: undetectable	2o4lA-5whtA: 24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R88_A_1LDA501_0 (CYTOSINE DEAMINASE)	5wht	PUTATIVE PERTUSSIS-LIKE TOXIN SUBUNIT (Salmonella enterica)	5 / 12	LEU A 125 PHE A 53 ILE A 55 GLU A 84 SER A 81	None	1.42A	4r88A-5whtA: undetectable	4r88A-5whtA: 16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R88_B_1LDB501_0 (CYTOSINE DEAMINASE)	5wht	PUTATIVE PERTUSSIS-LIKE TOXIN SUBUNIT (Salmonella enterica)	5 / 12	LEU A 125 PHE A 53 ILE A 55 GLU A 84 SER A 81	None	1.42A	4r88B-5whtA: undetectable	4r88B-5whtA: 16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R88_C_1LDC501_0 (CYTOSINE DEAMINASE)	5wht	PUTATIVE PERTUSSIS-LIKE TOXIN SUBUNIT (Salmonella enterica)	5 / 12	LEU A 125 PHE A 53 ILE A 55 GLU A 84 SER A 81	None	1.41A	4r88C-5whtA: undetectable	4r88C-5whtA: 16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R88_D_1LDD501_0 (CYTOSINE DEAMINASE)	5wht	PUTATIVE PERTUSSIS-LIKE TOXIN SUBUNIT (Salmonella enterica)	5 / 12	LEU A 125 PHE A 53 ILE A 55 GLU A 84 SER A 81	None	1.38A	4r88D-5whtA: undetectable	4r88D-5whtA: 16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R88_E_1LDE501_0 (CYTOSINE DEAMINASE)	5wht	PUTATIVE PERTUSSIS-LIKE TOXIN SUBUNIT (Salmonella enterica)	5 / 12	LEU A 125 PHE A 53 ILE A 55 GLU A 84 SER A 81	None	1.43A	4r88E-5whtA: undetectable	4r88E-5whtA: 16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R88_F_1LDF502_0 (CYTOSINE DEAMINASE)	5wht	PUTATIVE PERTUSSIS-LIKE TOXIN SUBUNIT (Salmonella enterica)	5 / 12	LEU A 125 PHE A 53 ILE A 55 GLU A 84 SER A 81	None	1.42A	4r88F-5whtA: undetectable	4r88F-5whtA: 16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CU6_A_ACTA403_0 (CASEIN KINASE II SUBUNIT ALPHA)	5wht	PUTATIVE PERTUSSIS-LIKE TOXIN SUBUNIT (Salmonella enterica)	4 / 6	TYR A 34 ILE A 55 VAL A 103 ALA A 69	SIA A 201 ( 4.2A) None None None	0.90A	5cu6A-5whtA: undetectable	5cu6A-5whtA: 20.39

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2O4L_A_TPVA403_1","PROTEASE","5wht","PUTATIVE PERTUSSIS-LIKE TOXIN SUBUNIT","Salmonella enterica",5,"ALA A  89;GLY A 124;VAL A 123;VAL A  68;ILE A  55","None","1.13A","2o4lA-5whtA:undetectable","2o4lA-5whtA:24.64"],["4R88_A_1LDA501_0","CYTOSINE DEAMINASE","5wht","PUTATIVE PERTUSSIS-LIKE TOXIN SUBUNIT","Salmonella enterica",5,"LEU A 125;PHE A  53;ILE A  55;GLU A  84;SER A  81","None","1.42A","4r88A-5whtA:undetectable","4r88A-5whtA:16.82"],["4R88_B_1LDB501_0","CYTOSINE DEAMINASE","5wht","PUTATIVE PERTUSSIS-LIKE TOXIN SUBUNIT","Salmonella enterica",5,"LEU A 125;PHE A  53;ILE A  55;GLU A  84;SER A  81","None","1.42A","4r88B-5whtA:undetectable","4r88B-5whtA:16.82"],["4R88_C_1LDC501_0","CYTOSINE DEAMINASE","5wht","PUTATIVE PERTUSSIS-LIKE TOXIN SUBUNIT","Salmonella enterica",5,"LEU A 125;PHE A  53;ILE A  55;GLU A  84;SER A  81","None","1.41A","4r88C-5whtA:undetectable","4r88C-5whtA:16.82"],["4R88_D_1LDD501_0","CYTOSINE DEAMINASE","5wht","PUTATIVE PERTUSSIS-LIKE TOXIN SUBUNIT","Salmonella enterica",5,"LEU A 125;PHE A  53;ILE A  55;GLU A  84;SER A  81","None","1.38A","4r88D-5whtA:undetectable","4r88D-5whtA:16.82"],["4R88_E_1LDE501_0","CYTOSINE DEAMINASE","5wht","PUTATIVE PERTUSSIS-LIKE TOXIN SUBUNIT","Salmonella enterica",5,"LEU A 125;PHE A  53;ILE A  55;GLU A  84;SER A  81","None","1.43A","4r88E-5whtA:undetectable","4r88E-5whtA:16.82"],["4R88_F_1LDF502_0","CYTOSINE DEAMINASE","5wht","PUTATIVE PERTUSSIS-LIKE TOXIN SUBUNIT","Salmonella enterica",5,"LEU A 125;PHE A  53;ILE A  55;GLU A  84;SER A  81","None","1.42A","4r88F-5whtA:undetectable","4r88F-5whtA:16.82"],["5CU6_A_ACTA403_0","CASEIN KINASE II SUBUNIT ALPHA","5wht","PUTATIVE PERTUSSIS-LIKE TOXIN SUBUNIT","Salmonella enterica",4,"TYR A  34;ILE A  55;VAL A 103;ALA A  69","SIA A 201 ( 4.2A);None;None;None","0.90A","5cu6A-5whtA:undetectable","5cu6A-5whtA:20.39"]]