SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wi2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 5wi2 CDNA FLJ56409,
HIGHLY SIMILAR TO
SERINE/THREONINE-PRO
TEIN KINASE CHK1 (EC
2.7.11.1)
(Homo
sapiens) 		5 / 10 PHE A 441
PHE A 426
PHE A 451
PHE A 380
ILE A 458
 None
 1.29A 3t3rD-5wi2A:
undetectable		 3t3rD-5wi2A:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TF1_A_ACTA191_0
(METHYL-ACCEPTING
CHEMOTAXIS PROTEIN)		 5wi2 CDNA FLJ56409,
HIGHLY SIMILAR TO
SERINE/THREONINE-PRO
TEIN KINASE CHK1 (EC
2.7.11.1)
(Homo
sapiens) 		4 / 5 THR A 382
ILE A 465
PHE A 380
LEU A 393
 None
 1.38A 3tf1A-5wi2A:
1.7		 3tf1A-5wi2A:
22.95