SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wi8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J6H_A_NCAA402_0
(H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, Q10 ALPHA
CHAIN)
5wi8 TUMOR NECROSIS
FACTOR RECEPTOR
SUPERFAMILY MEMBER 9

(Mus
musculus)
3 / 3 PRO A 107
ARG A 106
GLU A 153
None
0.97A 5j6hA-5wi8A:
undetectable
5j6hA-5wi8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)
5wi8 TUMOR NECROSIS
FACTOR RECEPTOR
SUPERFAMILY MEMBER 9

(Mus
musculus)
3 / 3 ASP A 104
ASN A 125
GLN A 127
None
0.80A 5k7uA-5wi8A:
undetectable
5k7uA-5wi8A:
undetectable