SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wi9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_C_AG2C7004_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 5wi9 -
(-) 		4 / 6 LEU A 463
LEU A 141
ASP A 137
LEU A 134
 None
 0.99A 1mt1D-5wi9A:
undetectable
1mt1E-5wi9A:
undetectable		 1mt1D-5wi9A:
undetectable
1mt1E-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_A_MTXA351_1
(PTERIDINE REDUCTASE
1)		 5wi9 -
(-) 		5 / 12 LEU A 178
TYR A 174
LEU A 141
LEU A 462
TYR A 149
 None
 1.19A 1p33A-5wi9A:
2.2		 1p33A-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_B_MTXB352_1
(PTERIDINE REDUCTASE
1)		 5wi9 -
(-) 		5 / 12 LEU A 178
TYR A 174
LEU A 141
LEU A 462
TYR A 149
 None
 1.23A 1p33B-5wi9A:
2.2		 1p33B-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 5wi9 -
(-) 		5 / 12 ILE A 298
ALA A 367
ARG A 411
LEU A 327
ILE A 403
 None
EDO  A 604 (-3.7A)
None
None
None
 1.41A 1y0xX-5wi9A:
undetectable		 1y0xX-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5wi9 -
(-) 		4 / 5 GLY A 465
GLN A  95
TRP A 468
SER A 461
 None
 1.21A 1zzqB-5wi9A:
undetectable		 1zzqB-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5wi9 -
(-) 		4 / 5 GLY A 465
GLN A  95
TRP A 468
SER A 461
 None
 1.20A 1zzuA-5wi9A:
0.3		 1zzuA-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2002_1
(SERUM ALBUMIN)		 5wi9 -
(-) 		5 / 11 LEU A 138
ILE A 187
ARG A 185
PHE A 148
GLY A  88
 None
 1.22A 2bxmA-5wi9A:
undetectable		 2bxmA-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2003_1
(SERUM ALBUMIN)		 5wi9 -
(-) 		5 / 10 LEU A 138
ILE A 187
ARG A 185
PHE A 148
GLY A  88
 None
 1.22A 2bxqA-5wi9A:
undetectable		 2bxqA-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 5wi9 -
(-) 		4 / 5 TYR A 457
TYR A 499
ILE A 502
GLY A 456
 None
 1.31A 2du8J-5wi9A:
undetectable		 2du8J-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)		 5wi9 -
(-) 		4 / 8 TYR A 221
TYR A 175
PHE A 229
GLY A 171
 None
 1.04A 2ha4A-5wi9A:
undetectable		 2ha4A-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_A_J01A1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 5wi9 -
(-) 		5 / 12 LEU A 141
SER A 130
ALA A 140
LEU A 178
TYR A 149
 None
 1.21A 2japA-5wi9A:
3.2		 2japA-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_B_J01B1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 5wi9 -
(-) 		5 / 12 LEU A 141
SER A 130
ALA A 140
LEU A 178
TYR A 149
 None
 1.17A 2japB-5wi9A:
2.6		 2japB-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_C_J01C1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 5wi9 -
(-) 		5 / 12 LEU A 141
SER A 130
ALA A 140
LEU A 178
TYR A 149
 None
 1.22A 2japC-5wi9A:
3.3		 2japC-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_D_J01D1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 5wi9 -
(-) 		5 / 12 LEU A 141
SER A 130
ALA A 140
LEU A 178
TYR A 149
 None
 1.19A 2japD-5wi9A:
3.4		 2japD-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_1
(THYMIDYLATE SYNTHASE)		 5wi9 -
(-) 		5 / 12 GLU A 135
LEU A 178
PHE A 133
VAL A  96
ALA A  93
 None
 1.36A 2kceA-5wi9A:
undetectable		 2kceA-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 5wi9 -
(-) 		4 / 5 LEU A 327
LEU A 300
LEU A 273
MET A 363
 None
 1.11A 2oaxF-5wi9A:
undetectable		 2oaxF-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1413_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 5wi9 -
(-) 		4 / 6 ALA A 371
ALA A 415
THR A 458
PHE A 148
 None
 0.93A 2xfhA-5wi9A:
undetectable		 2xfhA-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_2
(PROTEASE)		 5wi9 -
(-) 		4 / 6 ILE A 502
ILE A 190
GLY A  88
VAL A 454
 None
 0.88A 3n3iA-5wi9A:
undetectable		 3n3iA-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_B_ACTB601_0
(CHOLINE OXIDASE)		 5wi9 -
(-) 		4 / 5 TRP A 402
ILE A 305
HIS A 303
VAL A 326
 None
 1.09A 3nneB-5wi9A:
0.0		 3nneB-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_D_ACTD601_0
(CHOLINE OXIDASE)		 5wi9 -
(-) 		4 / 5 TRP A 402
ILE A 305
HIS A 303
VAL A 326
 None
 1.05A 3nneD-5wi9A:
undetectable		 3nneD-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_F_ACTF601_0
(CHOLINE OXIDASE)		 5wi9 -
(-) 		4 / 4 TRP A 402
ILE A 305
HIS A 303
VAL A 326
 None
 1.15A 3nneF-5wi9A:
0.0		 3nneF-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_ACTB1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 5wi9 -
(-) 		4 / 7 PRO A 257
ILE A 109
GLN A 203
GLY A 208
 None
 1.00A 4a3uB-5wi9A:
12.8		 4a3uB-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_1
(DIHYDROFOLATE
REDUCTASE)		 5wi9 -
(-) 		5 / 12 ILE A 412
ILE A 237
PHE A 370
PRO A 242
LEU A 327
 None
 1.03A 4m2xA-5wi9A:
undetectable		 4m2xA-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 5wi9 -
(-) 		5 / 9 PRO A 242
VAL A 245
ALA A 246
TYR A 250
GLY A 270
 None
 1.16A 4mm5A-5wi9A:
undetectable		 4mm5A-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)		 5wi9 -
(-) 		5 / 11 PRO A 242
VAL A 245
ALA A 246
TYR A 250
GLY A 270
 None
 1.18A 4mmaA-5wi9A:
0.7		 4mmaA-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)		 5wi9 -
(-) 		5 / 9 PRO A 242
VAL A 245
ALA A 246
TYR A 250
GLY A 270
 None
 1.15A 4mmbA-5wi9A:
undetectable		 4mmbA-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 5wi9 -
(-) 		5 / 10 PRO A 242
VAL A 245
ALA A 246
TYR A 250
GLY A 270
 None
 1.24A 4mmdA-5wi9A:
undetectable		 4mmdA-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 5wi9 -
(-) 		5 / 12 PRO A 242
VAL A 245
ALA A 246
TYR A 250
GLY A 270
 None
 1.20A 4mmdB-5wi9A:
undetectable		 4mmdB-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_B_MXMB807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5wi9 -
(-) 		5 / 12 LEU A 141
VAL A  96
PHE A 483
SER A 461
LEU A 462
 None
 1.10A 4o1zB-5wi9A:
undetectable		 4o1zB-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 5wi9 -
(-) 		5 / 10 GLY A 171
TYR A 174
ALA A  93
ILE A 153
LEU A 158
 None
 1.21A 4xj7A-5wi9A:
undetectable
4xj7B-5wi9A:
undetectable		 4xj7A-5wi9A:
undetectable
4xj7B-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_1
(WTFP-TAG,GP41)		 5wi9 -
(-) 		5 / 12 ALA A 371
SER A 373
ASN A 401
GLU A 398
LEU A 396
 None
 1.26A 5nwuA-5wi9A:
undetectable		 5nwuA-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 5wi9 -
(-) 		4 / 7 GLY A 249
TRP A 329
TYR A 340
TYR A 194
 None
 1.22A 5vlmG-5wi9A:
undetectable		 5vlmG-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5wi9 -
(-) 		4 / 5 TYR A 407
VAL A 443
MET A 323
GLY A 328
 None
 1.15A 6hd4A-5wi9A:
undetectable		 6hd4A-5wi9A:
undetectable