SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wj7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PJ7_A_FFOA2887_0 (N,N-DIMETHYLGLYCINE OXIDASE)	5wj7	DNA REPAIR PROTEIN XRCC4,MYOSIN-7 (Homo sapiens)	5 / 12	GLY A 77 PHE A 97 LEU A 74 TYR A 66 PHE A 106	None	1.42A	1pj7A-5wj7A: undetectable	1pj7A-5wj7A: 14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U7S_A_017A201_1 (POL POLYPROTEIN)	5wj7	DNA REPAIR PROTEIN XRCC4,MYOSIN-7 (Homo sapiens)	5 / 9	LEU A 126 ALA A 42 GLY A 45 ILE A 34 VAL A 122	None	0.87A	3u7sA-5wj7A: undetectable	3u7sA-5wj7A: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EJG_C_NCTC501_1 (CYTOCHROME P450 2A13)	5wj7	DNA REPAIR PROTEIN XRCC4,MYOSIN-7 (Homo sapiens)	4 / 7	PHE A 95 PHE A 111 ALA A 73 LEU A 28	None	0.66A	4ejgC-5wj7A: undetectable	4ejgC-5wj7A: 18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DJZ_A_GMJA301_0 (SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1)	5wj7	DNA REPAIR PROTEIN XRCC4,MYOSIN-7 (Homo sapiens)	5 / 12	LEU A 28 ILE A 34 LEU A 108 ALA A 73 TYR A 66	None	1.22A	6djzA-5wj7A: undetectable	6djzA-5wj7A: 21.99

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1PJ7_A_FFOA2887_0","N,N-DIMETHYLGLYCINE OXIDASE","5wj7","DNA REPAIR PROTEIN XRCC4,MYOSIN-7","Homo sapiens",5,"GLY A  77;PHE A  97;LEU A  74;TYR A  66;PHE A 106","None","1.42A","1pj7A-5wj7A:undetectable","1pj7A-5wj7A:14.53"],["3U7S_A_017A201_1","POL POLYPROTEIN","5wj7","DNA REPAIR PROTEIN XRCC4,MYOSIN-7","Homo sapiens",5,"LEU A 126;ALA A  42;GLY A  45;ILE A  34;VAL A 122","None","0.87A","3u7sA-5wj7A:undetectable","3u7sA-5wj7A:19.68"],["4EJG_C_NCTC501_1","CYTOCHROME P450 2A13","5wj7","DNA REPAIR PROTEIN XRCC4,MYOSIN-7","Homo sapiens",4,"PHE A  95;PHE A 111;ALA A  73;LEU A  28","None","0.66A","4ejgC-5wj7A:undetectable","4ejgC-5wj7A:18.43"],["6DJZ_A_GMJA301_0","SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1","5wj7","DNA REPAIR PROTEIN XRCC4,MYOSIN-7","Homo sapiens",5,"LEU A  28;ILE A  34;LEU A 108;ALA A  73;TYR A  66","None","1.22A","6djzA-5wj7A:undetectable","6djzA-5wj7A:21.99"]]