SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wj8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1122_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5wj8 CADHERIN-23
(Homo
sapiens) 		4 / 7 SER A1477
LYS A1485
SER A1434
VAL A1432
 None
 1.48A 2j9cA-5wj8A:
undetectable
2j9cB-5wj8A:
undetectable
2j9cC-5wj8A:
undetectable		 2j9cA-5wj8A:
undetectable
2j9cB-5wj8A:
undetectable
2j9cC-5wj8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_1
(O-METHYLTRANSFERASE)		 5wj8 CADHERIN-23
(Homo
sapiens) 		3 / 3 ASP A1487
PHE A1395
SER A1392
 None
 0.99A 3i5uB-5wj8A:
undetectable		 3i5uB-5wj8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_1
(POL POLYPROTEIN)		 5wj8 CADHERIN-23
(Homo
sapiens) 		5 / 9 ASP A1400
ALA A1416
ILE A1446
GLY A1454
ILE A1453
 None
 1.12A 3u7sA-5wj8A:
undetectable		 3u7sA-5wj8A:
16.33