SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wjm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0I_A_BEZA990_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 5wjm CADHERIN-23
(Mus
musculus) 		4 / 8 ASP A1892
ASP A1931
GLU A1929
SER A1838
 CA  A2006 (-3.2A)
CA  A2005 ( 2.7A)
None
None
 1.12A 2q0iA-5wjmA:
undetectable		 2q0iA-5wjmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 5wjm CADHERIN-23
(Mus
musculus) 		5 / 12 LEU A1891
PHE A1877
LEU A1922
VAL A1924
ILE A1867
 None
MPD  A2009 (-3.7A)
None
None
None
 0.96A 3sp9A-5wjmA:
undetectable		 3sp9A-5wjmA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CUT_A_TYLA2971_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 5wjm CADHERIN-23
(Mus
musculus) 		4 / 4 VAL A1924
VAL A1847
ASN A1871
ILE A1867
 None
 1.36A 4cutA-5wjmA:
undetectable		 4cutA-5wjmA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5wjm CADHERIN-23
(Mus
musculus) 		4 / 8 ASP A1787
ASN A1824
GLU A1733
ASP A1825
 CA  A2002 (-3.0A)
CA  A2003 (-4.8A)
CA  A2002 ( 2.9A)
None
 1.11A 4gkhC-5wjmA:
undetectable
4gkhK-5wjmA:
undetectable		 4gkhC-5wjmA:
15.02
4gkhK-5wjmA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5wjm CADHERIN-23
(Mus
musculus) 		4 / 8 ASP A1787
ASN A1824
GLU A1733
ASP A1825
 CA  A2002 (-3.0A)
CA  A2003 (-4.8A)
CA  A2002 ( 2.9A)
None
 1.14A 4gkiE-5wjmA:
undetectable
4gkiG-5wjmA:
undetectable		 4gkiE-5wjmA:
15.02
4gkiG-5wjmA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA604_1
(TRANSPORTER)		 5wjm CADHERIN-23
(Mus
musculus) 		4 / 7 ARG A1779
ILE A1816
PHE A1769
LEU A1786
 None
 1.12A 4mmcA-5wjmA:
undetectable		 4mmcA-5wjmA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)		 5wjm CADHERIN-23
(Mus
musculus) 		4 / 6 ARG A1889
ASP A1892
ARG A1895
LEU A1891
 None
CA  A2006 (-3.2A)
None
None
 1.13A 5tdzA-5wjmA:
undetectable		 5tdzA-5wjmA:
11.11