SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wk0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4002_1
(SERUM ALBUMIN)		 5wk0 DAMAGE-INDUCIBLE
PROTEIN DINB
(Staphylococcus
sp.
HMSC055H04) 		4 / 4 ARG A 102
ALA A 103
ALA A  55
GLU A  53
 None
 1.19A 1e7bA-5wk0A:
undetectable		 1e7bA-5wk0A:
9.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4002_1
(SERUM ALBUMIN)		 5wk0 DAMAGE-INDUCIBLE
PROTEIN DINB
(Staphylococcus
sp.
HMSC055H04) 		4 / 4 ARG A 102
ALA A 103
ALA A  55
GLU A  53
 None
 1.15A 1e7bB-5wk0A:
undetectable		 1e7bB-5wk0A:
9.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 5wk0 DAMAGE-INDUCIBLE
PROTEIN DINB
(Staphylococcus
sp.
HMSC055H04) 		4 / 5 ARG A 102
ALA A 103
ALA A  55
GLU A  53
 None
 1.23A 1e7cA-5wk0A:
undetectable		 1e7cA-5wk0A:
9.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5wk0 DAMAGE-INDUCIBLE
PROTEIN DINB
(Staphylococcus
sp.
HMSC055H04) 		3 / 3 LEU A 138
HIS A  47
ILE A  51
 None
NI  A 201 (-3.3A)
None
 0.71A 1s9pB-5wk0A:
undetectable		 1s9pB-5wk0A:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S38_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5wk0 DAMAGE-INDUCIBLE
PROTEIN DINB
(Staphylococcus
sp.
HMSC055H04) 		3 / 3 HIS A  47
HIS A 135
HIS A 139
 NI  A 201 (-3.3A)
NI  A 201 (-3.3A)
NI  A 201 (-3.3A)
 0.78A 3s38A-5wk0A:
undetectable		 3s38A-5wk0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3C_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5wk0 DAMAGE-INDUCIBLE
PROTEIN DINB
(Staphylococcus
sp.
HMSC055H04) 		3 / 3 HIS A  47
HIS A 135
HIS A 139
 NI  A 201 (-3.3A)
NI  A 201 (-3.3A)
NI  A 201 (-3.3A)
 0.78A 3s3cA-5wk0A:
3.4		 3s3cA-5wk0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_D_ACTD504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5wk0 DAMAGE-INDUCIBLE
PROTEIN DINB
(Staphylococcus
sp.
HMSC055H04) 		3 / 3 GLY A  76
SER A  77
TRP A  43
 None
 0.89A 4e7cD-5wk0A:
undetectable		 4e7cD-5wk0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A303_1
(ANCESTRAL STEROID
RECEPTOR 2)		 5wk0 DAMAGE-INDUCIBLE
PROTEIN DINB
(Staphylococcus
sp.
HMSC055H04) 		5 / 9 LEU A  56
ALA A 103
LEU A  14
PHE A  52
LEU A 125
 None
 1.40A 4ltwA-5wk0A:
undetectable		 4ltwA-5wk0A:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5wk0 DAMAGE-INDUCIBLE
PROTEIN DINB
(Staphylococcus
sp.
HMSC055H04) 		4 / 5 ILE A 149
LEU A 150
GLU A 145
VAL A  20
 None
 0.99A 4nkxB-5wk0A:
undetectable		 4nkxB-5wk0A:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECF_I_DVAI3010_0
(VLM2
DODECADEPSIPEPTIDE)		 5wk0 DAMAGE-INDUCIBLE
PROTEIN DINB
(Staphylococcus
sp.
HMSC055H04) 		3 / 3 PHE A  52
ARG A 102
ALA A  59
 None
 0.98A 6ecfB-5wk0A:
undetectable		 6ecfB-5wk0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5wk0 DAMAGE-INDUCIBLE
PROTEIN DINB
(Staphylococcus
sp.
HMSC055H04) 		3 / 3 HIS A  47
HIS A 135
HIS A 139
 NI  A 201 (-3.3A)
NI  A 201 (-3.3A)
NI  A 201 (-3.3A)
 0.66A 6giqa-5wk0A:
undetectable		 6giqa-5wk0A:
undetectable