SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wk1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		 5wk1 MAJOR CAPSID PROTEIN
(Pseudoalteromona
s
phage
TW1) 		5 / 11 LEU A 229
LEU A 210
LEU A 214
SER A 248
ILE A 247
 None
 0.97A 1ha2A-5wk1A:
undetectable		 1ha2A-5wk1A:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_A_HSMA401_1
(NITROPHORIN 1)		 5wk1 MAJOR CAPSID PROTEIN
(Pseudoalteromona
s
phage
TW1) 		4 / 4 ASP A 231
LEU A 226
LEU A 229
LEU A 227
 None
 1.30A 1u18A-5wk1A:
undetectable		 1u18A-5wk1A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HW2_A_RFPA1200_2
(RIFAMPIN ADP-RIBOSYL
TRANSFERASE)		 5wk1 MAJOR CAPSID PROTEIN
(Pseudoalteromona
s
phage
TW1) 		4 / 4 TRP A 183
LEU A 182
VAL A 205
LYS A 346
 None
 1.34A 2hw2A-5wk1A:
0.0		 2hw2A-5wk1A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_B_ADNB1302_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 5wk1 MAJOR CAPSID PROTEIN
(Pseudoalteromona
s
phage
TW1) 		4 / 6 TRP A 255
ALA A 272
ASN A 268
ALA A 271
 None
 1.18A 2zgwB-5wk1A:
undetectable		 2zgwB-5wk1A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 5wk1 MAJOR CAPSID PROTEIN
(Pseudoalteromona
s
phage
TW1) 		3 / 3 ASN A 264
ASN A 262
GLU A 219
 None
 0.81A 3kpdC-5wk1A:
undetectable		 3kpdC-5wk1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 5wk1 MAJOR CAPSID PROTEIN
(Pseudoalteromona
s
phage
TW1) 		3 / 3 ASN A 264
ASN A 262
GLU A 219
 None
 0.79A 3kpdB-5wk1A:
undetectable		 3kpdB-5wk1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_B_ADNB300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 5wk1 CAPSID STABILIZING
PROTEIN
(Pseudoalteromona
s
phage
TW1) 		5 / 11 ALA X  82
ILE X  42
GLY X  22
SER X  84
LEU X  57
 None
 1.07A 3kw2B-5wk1X:
undetectable		 3kw2B-5wk1X:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5wk1 CAPSID STABILIZING
PROTEIN
(Pseudoalteromona
s
phage
TW1) 		5 / 9 ILE X   8
GLY X  31
THR X  70
GLN X  62
GLY X  69
 None
 1.31A 4acaB-5wk1X:
undetectable
4acaC-5wk1X:
undetectable		 4acaB-5wk1X:
undetectable
4acaC-5wk1X:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FQS_A_LYAA302_1
(THYMIDYLATE SYNTHASE)		 5wk1 MAJOR CAPSID PROTEIN
(Pseudoalteromona
s
phage
TW1) 		5 / 12 GLU A 279
ILE A 277
LEU A 226
VAL A 223
ALA A 224
 None
 1.24A 4fqsA-5wk1A:
undetectable		 4fqsA-5wk1A:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FQS_B_LYAB302_1
(THYMIDYLATE SYNTHASE)		 5wk1 MAJOR CAPSID PROTEIN
(Pseudoalteromona
s
phage
TW1) 		5 / 12 GLU A 279
ILE A 277
LEU A 226
VAL A 223
ALA A 224
 None
 1.23A 4fqsB-5wk1A:
undetectable		 4fqsB-5wk1A:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_B_ACTB404_0
(D-ALANINE--D-ALANINE
LIGASE)		 5wk1 CAPSID STABILIZING
PROTEIN
(Pseudoalteromona
s
phage
TW1) 		4 / 7 LYS X  29
GLY X 140
SER X  94
LEU X 142
 None
 1.15A 5bphB-5wk1X:
undetectable		 5bphB-5wk1X:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)		 5wk1 MAJOR CAPSID PROTEIN
(Pseudoalteromona
s
phage
TW1) 		4 / 4 TYR A 350
GLY A 291
SER A 248
LEU A 289
 None
 1.41A 5bphC-5wk1A:
undetectable		 5bphC-5wk1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQY_A_BEZA401_0
(THIOREDOXIN)		 5wk1 CAPSID STABILIZING
PROTEIN
(Pseudoalteromona
s
phage
TW1) 		4 / 8 LYS X 104
VAL X 108
GLU X 131
CYH X 145
 None
 0.98A 5dqyA-5wk1X:
undetectable		 5dqyA-5wk1X:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_B_6J3B201_0
(TRANSTHYRETIN)		 5wk1 CAPSID STABILIZING
PROTEIN
(Pseudoalteromona
s
phage
TW1) 		4 / 6 LEU X  34
LEU X  57
SER X  84
THR X  19
 None
 1.29A 5l4iB-5wk1X:
undetectable		 5l4iB-5wk1X:
undetectable