SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wk4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 5wk4 VARIABLE LYMPHOCYTE
RECEPTOR 39
(Petromyzon
marinus) 		5 / 12 LEU D 102
LEU D  78
LEU D  54
LEU D  88
LEU D  85
 None
 1.00A 1sqnB-5wk4D:
undetectable		 1sqnB-5wk4D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TBF_A_VIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5wk4 VARIABLE LYMPHOCYTE
RECEPTOR 39
(Petromyzon
marinus) 		5 / 9 LEU D 104
LEU D  88
VAL D  68
LEU D  75
PHE D  93
 None
 1.28A 1tbfA-5wk4D:
undetectable		 1tbfA-5wk4D:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TBF_A_VIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5wk4 VARIABLE LYMPHOCYTE
RECEPTOR 39
(Petromyzon
marinus) 		5 / 9 LEU D 128
LEU D 112
VAL D  92
LEU D  99
PHE D 117
 None
 1.25A 1tbfA-5wk4D:
undetectable		 1tbfA-5wk4D:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)		 5wk4 VARIABLE LYMPHOCYTE
RECEPTOR 39
(Petromyzon
marinus) 		5 / 12 LEU D  54
LEU D 152
ILE D 136
VAL D 116
VAL D  92
 None
 1.12A 2ygnA-5wk4D:
undetectable		 2ygnA-5wk4D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)		 5wk4 VARIABLE LYMPHOCYTE
RECEPTOR 39
(Petromyzon
marinus) 		5 / 12 LEU D  56
LEU D 152
ILE D 136
VAL D 116
VAL D  92
 None
 1.03A 2ygnA-5wk4D:
undetectable		 2ygnA-5wk4D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN0_A_DMOA551_1
(ARGINASE-1)		 5wk4 VARIABLE LYMPHOCYTE
RECEPTOR 39
(Petromyzon
marinus) 		5 / 9 HIS D 106
ASP D  82
ASN D  79
GLY D  81
THR D 130
 None
 1.40A 3gn0A-5wk4D:
undetectable		 3gn0A-5wk4D:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN0_B_DMOB552_1
(ARGINASE-1)		 5wk4 VARIABLE LYMPHOCYTE
RECEPTOR 39
(Petromyzon
marinus) 		5 / 9 HIS D 106
ASP D  82
ASN D  79
GLY D  81
THR D 130
 None
 1.41A 3gn0B-5wk4D:
undetectable		 3gn0B-5wk4D:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_0
(REGULATORY PROTEIN
TETR)		 5wk4 VARIABLE LYMPHOCYTE
RECEPTOR 39
(Petromyzon
marinus) 		5 / 12 ALA D  45
LEU D  40
ILE D  61
VAL D  68
PHE D  69
 None
 1.23A 5vlmB-5wk4D:
undetectable		 5vlmB-5wk4D:
undetectable