SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wlg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ETA_1_T441128_1 (TRANSTHYRETIN)	5wlg	T CELL RECEPTOR ALPHA VARIABLE 8D-2,HUMAN NKT TCR ALPHA CHAIN CHIMERA (Homo sapiens; Mus musculus)	4 / 5	LYS D 55 GLU D 52 ALA D 62 LEU D 60	None	1.17A	1eta1-5wlgD: 3.8	1eta1-5wlgD: 19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ETA_2_T442129_1 (TRANSTHYRETIN)	5wlg	T CELL RECEPTOR ALPHA VARIABLE 8D-2,HUMAN NKT TCR ALPHA CHAIN CHIMERA (Homo sapiens; Mus musculus)	4 / 5	LYS D 55 GLU D 52 ALA D 62 LEU D 60	None	1.17A	1eta2-5wlgD: 4.2	1eta2-5wlgD: 19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ETB_1_T441128_1 (TRANSTHYRETIN)	5wlg	T CELL RECEPTOR ALPHA VARIABLE 8D-2,HUMAN NKT TCR ALPHA CHAIN CHIMERA (Homo sapiens; Mus musculus)	4 / 6	LYS D 55 GLU D 52 ALA D 62 LEU D 60	None	1.19A	1etb1-5wlgD: undetectable	1etb1-5wlgD: 19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QYN_A_RTLA201_0 (RETINOL-BINDING PROTEIN 2)	5wlg	T CELL RECEPTOR ALPHA VARIABLE 8D-2,HUMAN NKT TCR ALPHA CHAIN CHIMERA (Homo sapiens; Mus musculus)	5 / 12	ILE D 75 ALA D 84 THR D 90 VAL D 31 LEU D 73	None	1.36A	4qynA-5wlgD: undetectable	4qynA-5wlgD: 22.16

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ETA_1_T441128_1","TRANSTHYRETIN","5wlg","T CELL RECEPTOR ALPHA VARIABLE 8D-2,HUMAN NKT TCR ALPHA CHAIN CHIMERA","Homo sapiens;Mus musculus",4,"LYS D  55;GLU D  52;ALA D  62;LEU D  60","None","1.17A","1eta1-5wlgD:3.8","1eta1-5wlgD:19.35"],["1ETA_2_T442129_1","TRANSTHYRETIN","5wlg","T CELL RECEPTOR ALPHA VARIABLE 8D-2,HUMAN NKT TCR ALPHA CHAIN CHIMERA","Homo sapiens;Mus musculus",4,"LYS D  55;GLU D  52;ALA D  62;LEU D  60","None","1.17A","1eta2-5wlgD:4.2","1eta2-5wlgD:19.35"],["1ETB_1_T441128_1","TRANSTHYRETIN","5wlg","T CELL RECEPTOR ALPHA VARIABLE 8D-2,HUMAN NKT TCR ALPHA CHAIN CHIMERA","Homo sapiens;Mus musculus",4,"LYS D  55;GLU D  52;ALA D  62;LEU D  60","None","1.19A","1etb1-5wlgD:undetectable","1etb1-5wlgD:19.35"],["4QYN_A_RTLA201_0","RETINOL-BINDING PROTEIN 2","5wlg","T CELL RECEPTOR ALPHA VARIABLE 8D-2,HUMAN NKT TCR ALPHA CHAIN CHIMERA","Homo sapiens;Mus musculus",5,"ILE D  75;ALA D  84;THR D  90;VAL D  31;LEU D  73","None","1.36A","4qynA-5wlgD:undetectable","4qynA-5wlgD:22.16"]]