SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wln'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 5wln TYPE II SECRETION
SYSTEM PROTEIN D
(Pseudomonas
aeruginosa) 		4 / 7 LEU G 252
ILE G 292
VAL G 310
LEU G 313
 None
 0.59A 3r9vA-5wlnG:
undetectable
3r9vB-5wlnG:
undetectable		 3r9vA-5wlnG:
18.86
3r9vB-5wlnG:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5wln TYPE II SECRETION
SYSTEM PROTEIN D
(Pseudomonas
aeruginosa) 		5 / 12 SER G 268
ILE G 267
LEU G 301
LEU G 303
LEU G 313
 None
 1.07A 4xumA-5wlnG:
undetectable		 4xumA-5wlnG:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_4_BEZ4801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5wln TYPE II SECRETION
SYSTEM PROTEIN D
(Pseudomonas
aeruginosa) 		4 / 5 LEU G 414
ARG G 505
ILE G 333
ILE G 485
 None
 1.08A 5dzk4-5wlnG:
undetectable
5dzkg-5wlnG:
undetectable
5dzkm-5wlnG:
undetectable
5dzkn-5wlnG:
undetectable		 5dzk4-5wlnG:
0.66
5dzkg-5wlnG:
16.85
5dzkm-5wlnG:
15.70
5dzkn-5wlnG:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_V_BEZV801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 5wln TYPE II SECRETION
SYSTEM PROTEIN D
(Pseudomonas
aeruginosa) 		4 / 4 ILE G 333
ILE G 485
ARG G 505
LEU G 414
 None
 1.00A 5dzkh-5wlnG:
undetectable
5dzkn-5wlnG:
undetectable
5dzkv-5wlnG:
undetectable		 5dzkh-5wlnG:
15.70
5dzkn-5wlnG:
15.70
5dzkv-5wlnG:
0.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5wln TYPE II SECRETION
SYSTEM PROTEIN D
(Pseudomonas
aeruginosa) 		3 / 3 LYS G 359
ASN G 361
SER G 368
 None
 0.99A 5yw0A-5wlnG:
undetectable		 5yw0A-5wlnG:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5wln TYPE II SECRETION
SYSTEM PROTEIN D
(Pseudomonas
aeruginosa) 		5 / 9 THR G 309
SER G 268
GLY G 270
ILE G 267
ILE G 292
 None
 1.16A 6ebpA-5wlnG:
undetectable		 6ebpA-5wlnG:
7.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5wln TYPE II SECRETION
SYSTEM PROTEIN D
(Pseudomonas
aeruginosa) 		5 / 10 THR G 309
SER G 268
GLY G 270
ILE G 267
ILE G 292
 None
 1.17A 6ebpB-5wlnG:
undetectable		 6ebpB-5wlnG:
7.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5wln TYPE II SECRETION
SYSTEM PROTEIN D
(Pseudomonas
aeruginosa) 		5 / 10 THR G 309
SER G 268
GLY G 270
ILE G 267
ILE G 292
 None
 1.16A 6ebpC-5wlnG:
undetectable		 6ebpC-5wlnG:
7.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5wln TYPE II SECRETION
SYSTEM PROTEIN D
(Pseudomonas
aeruginosa) 		5 / 10 THR G 309
SER G 268
GLY G 270
ILE G 267
ILE G 292
 None
 1.14A 6ebpD-5wlnG:
undetectable		 6ebpD-5wlnG:
7.82