SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wlp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P7R_A_NCTA440_1 (CYTOCHROME P450-CAM)	5wlp	AUTOPHAGY-RELATED PROTEIN 32 (Saccharomyces cerevisiae)	4 / 7	PHE A 33 VAL A 120 VAL A 63 ILE A 65	None	0.93A	1p7rA-5wlpA: undetectable	1p7rA-5wlpA: 14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RC0_B_SAMB480_0 (N-LYSINE METHYLTRANSFERASE SETD6)	5wlp	AUTOPHAGY-RELATED PROTEIN 32 (Saccharomyces cerevisiae)	5 / 12	VAL A 88 GLY A 61 ALA A 54 LEU A 76 TYR A 82	None	1.19A	3rc0B-5wlpA: undetectable	3rc0B-5wlpA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AP6_A_TLFA300_0 (PROBABLE STRIGOLACTONE ESTERASE DAD2)	5wlp	AUTOPHAGY-RELATED PROTEIN 32 (Saccharomyces cerevisiae)	5 / 12	PHE A 66 PHE A 56 ILE A 79 VAL A 88 VAL A 73	None	1.36A	6ap6A-5wlpA: undetectable	6ap6A-5wlpA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AP6_B_TLFB300_0 (PROBABLE STRIGOLACTONE ESTERASE DAD2)	5wlp	AUTOPHAGY-RELATED PROTEIN 32 (Saccharomyces cerevisiae)	5 / 12	PHE A 66 PHE A 56 ILE A 79 VAL A 88 VAL A 73	None	1.36A	6ap6B-5wlpA: undetectable	6ap6B-5wlpA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1P7R_A_NCTA440_1","CYTOCHROME P450-CAM","5wlp","AUTOPHAGY-RELATED PROTEIN 32","Saccharomyces cerevisiae",4,"PHE A  33;VAL A 120;VAL A  63;ILE A  65","None","0.93A","1p7rA-5wlpA:undetectable","1p7rA-5wlpA:14.33"],["3RC0_B_SAMB480_0","N-LYSINE METHYLTRANSFERASE SETD6","5wlp","AUTOPHAGY-RELATED PROTEIN 32","Saccharomyces cerevisiae",5,"VAL A  88;GLY A  61;ALA A  54;LEU A  76;TYR A  82","None","1.19A","3rc0B-5wlpA:undetectable","3rc0B-5wlpA:undetectable"],["6AP6_A_TLFA300_0","PROBABLE STRIGOLACTONE ESTERASE DAD2","5wlp","AUTOPHAGY-RELATED PROTEIN 32","Saccharomyces cerevisiae",5,"PHE A  66;PHE A  56;ILE A  79;VAL A  88;VAL A  73","None","1.36A","6ap6A-5wlpA:undetectable","6ap6A-5wlpA:undetectable"],["6AP6_B_TLFB300_0","PROBABLE STRIGOLACTONE ESTERASE DAD2","5wlp","AUTOPHAGY-RELATED PROTEIN 32","Saccharomyces cerevisiae",5,"PHE A  66;PHE A  56;ILE A  79;VAL A  88;VAL A  73","None","1.36A","6ap6B-5wlpA:undetectable","6ap6B-5wlpA:undetectable"]]