SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wlz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 5wlz DNA REPAIR PROTEIN
XRCC4,MYOSIN-7
(Homo
sapiens) 		4 / 5 TYR C  84
TYR C  94
ILE C  34
GLY C  77
 None
 1.14A 1kifA-5wlzC:
undetectable		 1kifA-5wlzC:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 5wlz DNA REPAIR PROTEIN
XRCC4,MYOSIN-7
(Homo
sapiens) 		4 / 5 TYR C  84
TYR C  94
ILE C  34
GLY C  77
 None
 1.14A 1kifB-5wlzC:
undetectable		 1kifB-5wlzC:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 5wlz DNA REPAIR PROTEIN
XRCC4,MYOSIN-7
(Homo
sapiens) 		4 / 5 TYR C  84
TYR C  94
ILE C  34
GLY C  77
 None
 1.14A 1kifC-5wlzC:
undetectable		 1kifC-5wlzC:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 5wlz DNA REPAIR PROTEIN
XRCC4,MYOSIN-7
(Homo
sapiens) 		4 / 5 TYR C  84
TYR C  94
ILE C  34
GLY C  77
 None
 1.14A 1kifD-5wlzC:
undetectable		 1kifD-5wlzC:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 5wlz DNA REPAIR PROTEIN
XRCC4,MYOSIN-7
(Homo
sapiens) 		4 / 5 TYR C  84
TYR C  94
ILE C  34
GLY C  77
 None
 1.14A 1kifE-5wlzC:
undetectable		 1kifE-5wlzC:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 5wlz DNA REPAIR PROTEIN
XRCC4,MYOSIN-7
(Homo
sapiens) 		4 / 5 TYR C  84
TYR C  94
ILE C  34
GLY C  77
 None
 1.14A 1kifF-5wlzC:
undetectable		 1kifF-5wlzC:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 5wlz DNA REPAIR PROTEIN
XRCC4,MYOSIN-7
(Homo
sapiens) 		4 / 5 TYR C  84
TYR C  94
ILE C  34
GLY C  77
 None
 1.14A 1kifG-5wlzC:
undetectable		 1kifG-5wlzC:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 5wlz DNA REPAIR PROTEIN
XRCC4,MYOSIN-7
(Homo
sapiens) 		4 / 5 TYR C  84
TYR C  94
ILE C  34
GLY C  77
 None
 1.14A 1kifH-5wlzC:
undetectable		 1kifH-5wlzC:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 5wlz DNA REPAIR PROTEIN
XRCC4,MYOSIN-7
(Homo
sapiens) 		4 / 5 TYR C  84
TYR C  94
ILE C  34
GLY C  77
 None
 1.14A 1ve9A-5wlzC:
undetectable		 1ve9A-5wlzC:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 5wlz DNA REPAIR PROTEIN
XRCC4,MYOSIN-7
(Homo
sapiens) 		4 / 5 TYR C  84
TYR C  94
ILE C  34
GLY C  77
 None
 1.16A 2du8G-5wlzC:
undetectable		 2du8G-5wlzC:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 5wlz DNA REPAIR PROTEIN
XRCC4,MYOSIN-7
(Homo
sapiens) 		4 / 5 TYR C  84
TYR C  94
ILE C  34
GLY C  77
 None
 1.30A 2du8J-5wlzC:
undetectable		 2du8J-5wlzC:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_1
(POL POLYPROTEIN)		 5wlz DNA REPAIR PROTEIN
XRCC4,MYOSIN-7
(Homo
sapiens) 		5 / 9 LEU C 126
ALA C  42
GLY C  45
ILE C  34
VAL C 122
 None
 0.92A 3u7sA-5wlzC:
undetectable		 3u7sA-5wlzC:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5wlz DNA REPAIR PROTEIN
XRCC4,MYOSIN-7
(Homo
sapiens) 		4 / 7 HIS C  40
ASP C  38
SER C  89
PHE C  88
 None
 1.31A 4ndnC-5wlzC:
undetectable		 4ndnC-5wlzC:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5wlz DNA REPAIR PROTEIN
XRCC4,MYOSIN-7
(Homo
sapiens) 		4 / 7 HIS C  40
ASP C  38
SER C  89
PHE C  88
 None
 1.28A 5a1iA-5wlzC:
undetectable		 5a1iA-5wlzC:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CVT_B_ACTB200_0
(N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE)		 5wlz DNA REPAIR PROTEIN
XRCC4,MYOSIN-7
(Homo
sapiens) 		3 / 3 ASN C 118
ALA C 120
ARG C 124
 None
 0.36A 5cvtB-5wlzC:
undetectable		 5cvtB-5wlzC:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 5wlz DNA REPAIR PROTEIN
XRCC4,MYOSIN-7
(Homo
sapiens) 		4 / 7 SER C  53
ALA C  56
GLY C  64
VAL C  67
 None
 0.71A 5fpdA-5wlzC:
undetectable		 5fpdA-5wlzC:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 5wlz DNA REPAIR PROTEIN
XRCC4,MYOSIN-7
(Homo
sapiens) 		5 / 12 LEU C  28
ILE C  34
LEU C 108
ALA C  73
TYR C  66
 None
 1.18A 6djzA-5wlzC:
undetectable		 6djzA-5wlzC:
18.80