SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wn9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 5wn9 SCFV 2D10
(Homo
sapiens) 		3 / 3 ALA H 108
VAL H  34
TRP H  36
 None
 0.90A 1tkqA-5wn9H:
undetectable		 1tkqA-5wn9H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_B_CHDB1086_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 5wn9 SCFV 2D10
(Homo
sapiens) 		5 / 11 MET H  48
GLY H  49
GLN H 233
THR H 235
GLY H  97
 None
 1.12A 3ablA-5wn9H:
undetectable
3ablB-5wn9H:
undetectable
3ablT-5wn9H:
undetectable		 3ablA-5wn9H:
undetectable
3ablB-5wn9H:
undetectable
3ablT-5wn9H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 5wn9 SCFV 2D10
(Homo
sapiens) 		5 / 11 MET H  48
GLY H  49
GLN H 233
THR H 235
GLY H  97
 None
 1.02A 3ag3A-5wn9H:
undetectable
3ag3B-5wn9H:
undetectable
3ag3T-5wn9H:
undetectable		 3ag3A-5wn9H:
undetectable
3ag3B-5wn9H:
undetectable
3ag3T-5wn9H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 5wn9 SCFV 2D10
(Homo
sapiens) 		5 / 11 GLY H  97
MET H  48
GLY H  49
GLN H 233
THR H 235
 None
 1.12A 3ag3G-5wn9H:
undetectable
3ag3N-5wn9H:
undetectable
3ag3O-5wn9H:
undetectable		 3ag3G-5wn9H:
undetectable
3ag3N-5wn9H:
undetectable
3ag3O-5wn9H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 5wn9 SCFV 2D10
(Homo
sapiens) 		5 / 11 GLY H  97
MET H  48
GLY H  49
GLN H 233
THR H 235
 None
 1.06A 5b1bG-5wn9H:
undetectable
5b1bN-5wn9H:
undetectable
5b1bO-5wn9H:
undetectable		 5b1bG-5wn9H:
undetectable
5b1bN-5wn9H:
undetectable
5b1bO-5wn9H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC503_0
(ADENOSYLHOMOCYSTEINA
SE)		 5wn9 SCFV 2D10
(Homo
sapiens) 		5 / 12 GLY H  97
GLY H 115
SER H  35
VAL H  37
GLN H 233
 None
 0.93A 6exiC-5wn9H:
undetectable
6exiD-5wn9H:
undetectable		 6exiC-5wn9H:
22.58
6exiD-5wn9H:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_B_CHDB304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 5wn9 SCFV 2D10
(Homo
sapiens) 		5 / 11 MET H  48
GLY H  49
GLN H 233
THR H 235
GLY H  97
 None
 1.08A 6nknA-5wn9H:
undetectable
6nknB-5wn9H:
undetectable
6nknT-5wn9H:
undetectable		 6nknA-5wn9H:
undetectable
6nknB-5wn9H:
undetectable
6nknT-5wn9H:
undetectable