SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wna'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_2
(POL POLYPROTEIN)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
4 / 7 ASP H  62
VAL H  64
GLY H  50
ILE H  51
None
0.76A 1t7iB-5wnaH:
undetectable
1t7iB-5wnaH:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB8_0
(GRAMICIDIN A)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
4 / 5 VAL H  23
GLY H  24
VAL H   5
TRP H 114
None
1.28A 1tkqB-5wnaH:
undetectable
1tkqB-5wnaH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2887_1
(AMINOMETHYLTRANSFERA
SE)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
3 / 3 ASP H 112
GLU H   6
ARG H  72
None
0.80A 1wopA-5wnaH:
2.0
1wopA-5wnaH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_1
(PROTEASE)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
4 / 8 ASP H  62
VAL H  64
GLY H  50
ILE H  51
None
0.77A 3nu9A-5wnaH:
undetectable
3nu9A-5wnaH:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
5 / 12 GLY H  24
ILE H  98
VAL H 100
ASN H  54
LEU H  79
None
1.21A 4a81A-5wnaH:
undetectable
4a81A-5wnaH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
5 / 11 SER H 199
GLY H 145
THR H 146
ALA H 147
THR H 142
None
0.84A 4qvnH-5wnaH:
undetectable
4qvnI-5wnaH:
undetectable
4qvnH-5wnaH:
18.50
4qvnI-5wnaH:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
5 / 10 SER H 199
GLY H 145
THR H 146
ALA H 147
THR H 142
None
0.84A 4qvnV-5wnaH:
undetectable
4qvnW-5wnaH:
undetectable
4qvnV-5wnaH:
18.50
4qvnW-5wnaH:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
5 / 12 SER H 199
GLY H 145
THR H 146
ALA H 147
THR H 142
None
0.82A 4qvpH-5wnaH:
undetectable
4qvpI-5wnaH:
undetectable
4qvpH-5wnaH:
18.50
4qvpI-5wnaH:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
5 / 12 SER H 199
GLY H 145
THR H 146
ALA H 147
THR H 142
None
0.82A 4qvpV-5wnaH:
undetectable
4qvpW-5wnaH:
undetectable
4qvpV-5wnaH:
18.50
4qvpW-5wnaH:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
5 / 11 SER H 199
GLY H 145
THR H 146
ALA H 147
THR H 142
None
0.83A 4qvqH-5wnaH:
undetectable
4qvqI-5wnaH:
undetectable
4qvqH-5wnaH:
18.50
4qvqI-5wnaH:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
5 / 11 SER H 199
GLY H 145
THR H 146
ALA H 147
THR H 142
None
0.82A 4qvqV-5wnaH:
undetectable
4qvqW-5wnaH:
undetectable
4qvqV-5wnaH:
18.50
4qvqW-5wnaH:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
5 / 11 SER H 199
GLY H 145
THR H 146
ALA H 147
THR H 142
None
0.86A 4qvvH-5wnaH:
undetectable
4qvvH-5wnaH:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
5 / 11 SER H 199
GLY H 145
THR H 146
ALA H 147
THR H 142
None
0.86A 4qvvV-5wnaH:
undetectable
4qvvV-5wnaH:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
5 / 11 SER H 199
GLY H 145
THR H 146
ALA H 147
THR H 142
None
0.84A 4qvyH-5wnaH:
undetectable
4qvyH-5wnaH:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
5 / 12 SER H 199
GLY H 145
THR H 146
ALA H 147
THR H 142
None
0.84A 4qvyV-5wnaH:
undetectable
4qvyW-5wnaH:
undetectable
4qvyV-5wnaH:
18.50
4qvyW-5wnaH:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
5 / 11 SER H 199
GLY H 145
THR H 146
ALA H 147
THR H 142
None
0.84A 4qw0H-5wnaH:
undetectable
4qw0I-5wnaH:
undetectable
4qw0H-5wnaH:
18.50
4qw0I-5wnaH:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
5 / 11 SER H 199
GLY H 145
THR H 146
ALA H 147
THR H 142
None
0.84A 4qw0V-5wnaH:
undetectable
4qw0W-5wnaH:
undetectable
4qw0V-5wnaH:
18.50
4qw0W-5wnaH:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
5 / 12 SER H 199
GLY H 145
THR H 146
ALA H 147
THR H 142
None
0.85A 4qw1H-5wnaH:
undetectable
4qw1I-5wnaH:
undetectable
4qw1H-5wnaH:
18.50
4qw1I-5wnaH:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
5 / 12 SER H 199
GLY H 145
THR H 146
ALA H 147
THR H 142
None
0.85A 4qw1V-5wnaH:
undetectable
4qw1W-5wnaH:
undetectable
4qw1V-5wnaH:
18.50
4qw1W-5wnaH:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
5 / 11 SER H 199
GLY H 145
THR H 146
ALA H 147
THR H 142
None
0.85A 4qwuH-5wnaH:
undetectable
4qwuI-5wnaH:
undetectable
4qwuH-5wnaH:
18.50
4qwuI-5wnaH:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
5 / 11 SER H 199
GLY H 145
THR H 146
ALA H 147
THR H 142
None
0.85A 4qwuV-5wnaH:
undetectable
4qwuW-5wnaH:
undetectable
4qwuV-5wnaH:
18.50
4qwuW-5wnaH:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)
5wna MAB 3D3 FAB HEAVY
CHAIN
MAJOR SURFACE
GLYCOPROTEIN G

(Homo
sapiens;
Human
orthopneumovirus)
5 / 10 ILE B 189
GLU H  30
ASN H  74
LEU H  79
LEU H  27
None
1.26A 4r3aB-5wnaB:
undetectable
4r3aB-5wnaB:
5.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
5 / 11 SER H 199
GLY H 145
THR H 146
ALA H 147
THR H 142
None
0.83A 5bxnH-5wnaH:
undetectable
5bxnI-5wnaH:
undetectable
5bxnH-5wnaH:
16.37
5bxnI-5wnaH:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
5 / 12 SER H 199
GLY H 145
THR H 146
ALA H 147
THR H 142
None
0.84A 5cz7V-5wnaH:
undetectable
5cz7W-5wnaH:
undetectable
5cz7V-5wnaH:
18.50
5cz7W-5wnaH:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
5 / 11 SER H 199
GLY H 145
THR H 146
ALA H 147
THR H 142
None
0.83A 5d0xV-5wnaH:
undetectable
5d0xV-5wnaH:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
5 / 12 SER H 199
GLY H 145
THR H 146
ALA H 147
THR H 142
None
0.80A 5l5fH-5wnaH:
undetectable
5l5fI-5wnaH:
undetectable
5l5fH-5wnaH:
18.50
5l5fI-5wnaH:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
5 / 12 SER H 199
GLY H 145
THR H 146
ALA H 147
THR H 142
None
0.81A 5l5fV-5wnaH:
undetectable
5l5fW-5wnaH:
undetectable
5l5fV-5wnaH:
18.50
5l5fW-5wnaH:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
5 / 12 SER H 199
GLY H 145
THR H 146
ALA H 147
THR H 142
None
0.85A 5l66H-5wnaH:
undetectable
5l66I-5wnaH:
undetectable
5l66H-5wnaH:
18.50
5l66I-5wnaH:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
5 / 12 SER H 199
GLY H 145
THR H 146
ALA H 147
THR H 142
None
0.84A 5l66V-5wnaH:
undetectable
5l66W-5wnaH:
undetectable
5l66V-5wnaH:
18.50
5l66W-5wnaH:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_A_SAMA505_0
(CARNOSINE
N-METHYLTRANSFERASE)
5wna MAJOR SURFACE
GLYCOPROTEIN G
MAB 3D3 FAB HEAVY
CHAIN

(Human
orthopneumovirus
;
Homo
sapiens)
5 / 12 GLY H  59
GLY H  50
ASN B 161
SER H  55
PHE H  68
None
1.35A 5yf0A-5wnaH:
undetectable
5yf0A-5wnaH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_H_BO2H301_0
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
5 / 12 SER H 199
GLY H 145
THR H 146
ALA H 147
THR H 142
None
0.92A 6hwdH-5wnaH:
undetectable
6hwdI-5wnaH:
undetectable
6hwdH-5wnaH:
19.54
6hwdI-5wnaH:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_V_BO2V301_0
(PROTEASOME SUBUNIT
BETA TYPE-2)
5wna MAB 3D3 FAB HEAVY
CHAIN

(Homo
sapiens)
5 / 11 SER H 199
GLY H 145
THR H 146
ALA H 147
THR H 142
None
0.92A 6hwdV-5wnaH:
undetectable
6hwdV-5wnaH:
19.54