SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wnm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUO_A_ADNA1_1
(AURORA-RELATED
KINASE 1)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		6 / 9 GLY A  29
VAL A  36
ALA A  49
LEU A  82
TYR A  98
LEU A 150
 VX6  A 402 ( 4.2A)
VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
VX6  A 402 ( 4.8A)
VX6  A 402 (-4.3A)
VX6  A 402 (-4.4A)
 0.65A 1muoA-5wnmA:
8.4		 1muoA-5wnmA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_H_BEZH515_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		4 / 6 PHE A 223
ALA A 186
TYR A 207
ILE A 193
 None
 1.21A 1oniH-5wnmA:
undetectable
1oniI-5wnmA:
undetectable		 1oniH-5wnmA:
undetectable
1oniI-5wnmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_A_BAXA1723_1
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		5 / 12 ALA A  49
GLU A  69
LEU A  82
LEU A 132
HIS A 141
 VX6  A 402 (-3.2A)
VX6  A 402 (-4.4A)
VX6  A 402 ( 4.8A)
None
None
 0.51A 1uwhA-5wnmA:
29.1		 1uwhA-5wnmA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_A_BAXA1723_1
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		6 / 12 VAL A  36
ALA A  49
GLU A  69
LEU A  82
LEU A 132
HIS A 141
 VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
VX6  A 402 (-4.4A)
VX6  A 402 ( 4.8A)
None
None
 0.54A 1uwjA-5wnmA:
9.0		 1uwjA-5wnmA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_B_BAXB1723_1
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		6 / 12 VAL A  36
ALA A  49
GLU A  69
LEU A  82
LEU A 132
HIS A 141
 VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
VX6  A 402 (-4.4A)
VX6  A 402 ( 4.8A)
None
None
 0.54A 1uwjB-5wnmA:
9.1		 1uwjB-5wnmA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XBB_A_STIA1_1
(TYROSINE-PROTEIN
KINASE SYK)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		5 / 9 VAL A  36
ALA A  49
MET A  96
GLY A 102
LEU A 150
 VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
VX6  A 402 (-3.7A)
VX6  A 402 (-3.5A)
VX6  A 402 (-4.4A)
 0.35A 1xbbA-5wnmA:
29.4		 1xbbA-5wnmA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EVA_A_ADNA498_1
(TAK1 KINASE - TAB1
CHIMERA FUSION
PROTEIN)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		7 / 11 VAL A  28
GLY A  29
GLY A  34
VAL A  36
ALA A  49
MET A  96
TYR A  98
 VX6  A 402 ( 4.2A)
VX6  A 402 ( 4.2A)
None
VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
VX6  A 402 (-3.7A)
VX6  A 402 (-4.3A)
 1.40A 2evaA-5wnmA:
28.4		 2evaA-5wnmA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EVA_A_ADNA498_1
(TAK1 KINASE - TAB1
CHIMERA FUSION
PROTEIN)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		8 / 11 VAL A  28
GLY A  29
VAL A  36
ALA A  49
MET A  96
TYR A  98
SER A 103
LEU A 150
 VX6  A 402 ( 4.2A)
VX6  A 402 ( 4.2A)
VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
VX6  A 402 (-3.7A)
VX6  A 402 (-4.3A)
VX6  A 402 ( 4.7A)
VX6  A 402 (-4.4A)
 0.68A 2evaA-5wnmA:
28.4		 2evaA-5wnmA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_A_STIA600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		6 / 12 VAL A  36
ALA A  49
GLU A  69
MET A  73
GLY A 102
LEU A 150
 VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
VX6  A 402 (-4.4A)
None
VX6  A 402 (-3.5A)
VX6  A 402 (-4.4A)
 0.83A 2hyyA-5wnmA:
27.7		 2hyyA-5wnmA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITO_A_IREA2020_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		6 / 12 ALA A  49
GLU A  69
MET A  73
LEU A  94
GLY A 102
LEU A 150
 VX6  A 402 (-3.2A)
VX6  A 402 (-4.4A)
None
None
VX6  A 402 (-3.5A)
VX6  A 402 (-4.4A)
 0.71A 2itoA-5wnmA:
28.5		 2itoA-5wnmA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIQ_A_STIA1001_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		8 / 12 ALA A  49
LYS A  51
GLU A  69
MET A  73
TYR A  98
GLY A 102
LEU A 150
ASP A 161
 VX6  A 402 (-3.2A)
VX6  A 402 (-4.9A)
VX6  A 402 (-4.4A)
None
VX6  A 402 (-4.3A)
VX6  A 402 (-3.5A)
VX6  A 402 (-4.4A)
VX6  A 402 (-4.3A)
 1.04A 2oiqA-5wnmA:
25.9		 2oiqA-5wnmA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIQ_A_STIA1001_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		8 / 12 VAL A  36
ALA A  49
LYS A  51
GLU A  69
MET A  73
TYR A  98
GLY A 102
LEU A 150
 VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
VX6  A 402 (-4.9A)
VX6  A 402 (-4.4A)
None
VX6  A 402 (-4.3A)
VX6  A 402 (-3.5A)
VX6  A 402 (-4.4A)
 0.82A 2oiqA-5wnmA:
25.9		 2oiqA-5wnmA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PL0_A_STIA200_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE LCK)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		7 / 12 ALA A  49
LYS A  51
GLU A  69
MET A  73
TYR A  98
LEU A 150
ASP A 161
 VX6  A 402 (-3.2A)
VX6  A 402 (-4.9A)
VX6  A 402 (-4.4A)
None
VX6  A 402 (-4.3A)
VX6  A 402 (-4.4A)
VX6  A 402 (-4.3A)
 0.97A 2pl0A-5wnmA:
26.1		 2pl0A-5wnmA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WGJ_A_VGHA2346_1
(HEPATOCYTE GROWTH
FACTOR RECEPTOR)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		8 / 12 GLY A  29
VAL A  36
ALA A  49
LEU A  82
TYR A  98
MET A  99
GLY A 102
ASP A 161
 VX6  A 402 ( 4.2A)
VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
VX6  A 402 ( 4.8A)
VX6  A 402 (-4.3A)
None
VX6  A 402 (-3.5A)
VX6  A 402 (-4.3A)
 0.68A 2wgjA-5wnmA:
27.3		 2wgjA-5wnmA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XP2_A_VGHA9000_1
(TYROSINE-PROTEIN
KINASE RECEPTOR)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		6 / 9 VAL A  36
ALA A  49
MET A  99
GLY A 102
LEU A 150
ASP A 161
 VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
None
VX6  A 402 (-3.5A)
VX6  A 402 (-4.4A)
VX6  A 402 (-4.3A)
 0.50A 2xp2A-5wnmA:
28.8		 2xp2A-5wnmA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6O_A_1N1A1892_1
(EPHRIN TYPE-A
RECEPTOR 4)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		7 / 12 ALA A  49
GLU A  69
MET A  73
TYR A  98
GLY A 102
LEU A 150
SER A 160
 VX6  A 402 (-3.2A)
VX6  A 402 (-4.4A)
None
VX6  A 402 (-4.3A)
VX6  A 402 (-3.5A)
VX6  A 402 (-4.4A)
VX6  A 402 (-3.3A)
 0.64A 2y6oA-5wnmA:
28.4		 2y6oA-5wnmA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_A_BEZA302_0
(DISULFIDE
INTERCHANGE PROTEIN)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		4 / 6 HIS A 141
LEU A 132
LYS A  72
ALA A  76
 None
 1.25A 3gv1A-5wnmA:
undetectable
3gv1C-5wnmA:
undetectable		 3gv1A-5wnmA:
undetectable
3gv1C-5wnmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB301_0
(DISULFIDE
INTERCHANGE PROTEIN)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		4 / 6 LEU A 132
LYS A  72
ALA A  76
HIS A 141
 None
 1.26A 3gv1A-5wnmA:
undetectable
3gv1B-5wnmA:
undetectable		 3gv1A-5wnmA:
undetectable
3gv1B-5wnmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K54_A_1N1A1_1
(TYROSINE-PROTEIN
KINASE BTK)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		7 / 12 ALA A  49
GLU A  69
MET A  73
TYR A  98
GLY A 102
LEU A 150
SER A 160
 VX6  A 402 (-3.2A)
VX6  A 402 (-4.4A)
None
VX6  A 402 (-4.3A)
VX6  A 402 (-3.5A)
VX6  A 402 (-4.4A)
VX6  A 402 (-3.3A)
 0.69A 3k54A-5wnmA:
27.6		 3k54A-5wnmA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LFA_A_1N1A361_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		5 / 8 VAL A  28
ALA A  49
GLU A  69
LEU A  94
MET A  99
 VX6  A 402 ( 4.2A)
VX6  A 402 (-3.2A)
VX6  A 402 (-4.4A)
None
None
 0.68A 3lfaA-5wnmA:
20.6		 3lfaA-5wnmA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIY_B_B49B2_1
(TYROSINE-PROTEIN
KINASE ITK/TSK)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		5 / 9 ALA A  49
MET A  99
GLY A 102
LEU A 150
SER A 160
 VX6  A 402 (-3.2A)
None
VX6  A 402 (-3.5A)
VX6  A 402 (-4.4A)
VX6  A 402 (-3.3A)
 0.58A 3miyB-5wnmA:
28.9		 3miyB-5wnmA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OEZ_A_STIA601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		6 / 12 VAL A  36
ALA A  49
GLU A  69
TYR A  98
GLY A 102
LEU A 150
 VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
VX6  A 402 (-4.4A)
VX6  A 402 (-4.3A)
VX6  A 402 (-3.5A)
VX6  A 402 (-4.4A)
 0.57A 3oezA-5wnmA:
26.4		 3oezA-5wnmA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXR_B_1N1B2_1
(CYTOPLASMIC
TYROSINE-PROTEIN
KINASE BMX)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		6 / 12 VAL A  36
ALA A  49
MET A  73
TYR A  98
GLY A 102
LEU A 150
 VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
None
VX6  A 402 (-4.3A)
VX6  A 402 (-3.5A)
VX6  A 402 (-4.4A)
 0.47A 3sxrB-5wnmA:
27.8		 3sxrB-5wnmA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_1
(GLYCINE
N-METHYLTRANSFERASE)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		3 / 3 LEU A 132
HIS A 133
MET A 129
 None
 0.95A 3thrD-5wnmA:
undetectable		 3thrD-5wnmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_D_C2FD1200_0
(GLYCINE
N-METHYLTRANSFERASE)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		5 / 12 MET A  73
SER A 208
LEU A 132
HIS A 133
MET A 129
 None
 1.47A 3thrA-5wnmA:
undetectable
3thrB-5wnmA:
undetectable
3thrC-5wnmA:
undetectable
3thrD-5wnmA:
undetectable		 3thrA-5wnmA:
undetectable
3thrB-5wnmA:
undetectable
3thrC-5wnmA:
undetectable
3thrD-5wnmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UG2_A_IREA1_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		7 / 12 VAL A  36
ALA A  49
LEU A  94
MET A  96
MET A  99
GLY A 102
LEU A 150
 VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
None
VX6  A 402 (-3.7A)
None
VX6  A 402 (-3.5A)
VX6  A 402 (-4.4A)
 0.64A 3ug2A-5wnmA:
27.6		 3ug2A-5wnmA:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZBF_A_VGHA3000_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ROS)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		6 / 12 ALA A  49
LEU A  82
MET A  99
GLY A 102
LEU A 150
ASP A 161
 VX6  A 402 (-3.2A)
VX6  A 402 ( 4.8A)
None
VX6  A 402 (-3.5A)
VX6  A 402 (-4.4A)
VX6  A 402 (-4.3A)
 0.52A 3zbfA-5wnmA:
29.0		 3zbfA-5wnmA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		5 / 9 MET A  73
ILE A  81
TYR A  98
MET A  99
ILE A 159
 None
None
VX6  A 402 (-4.3A)
None
None
 0.71A 3zosA-5wnmA:
25.6		 3zosA-5wnmA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_B_0LIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		5 / 9 MET A  73
ILE A  81
TYR A  98
MET A  99
ILE A 159
 None
None
VX6  A 402 (-4.3A)
None
None
 0.72A 3zosB-5wnmA:
26.0		 3zosB-5wnmA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ANQ_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		6 / 9 VAL A  36
ALA A  49
MET A  99
GLY A 102
LEU A 150
ASP A 161
 VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
None
VX6  A 402 (-3.5A)
VX6  A 402 (-4.4A)
VX6  A 402 (-4.3A)
 0.53A 4anqA-5wnmA:
28.2		 4anqA-5wnmA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ANS_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		7 / 9 VAL A  36
ALA A  49
MET A  96
MET A  99
GLY A 102
LEU A 150
ASP A 161
 VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
VX6  A 402 (-3.7A)
None
VX6  A 402 (-3.5A)
VX6  A 402 (-4.4A)
VX6  A 402 (-4.3A)
 0.58A 4ansA-5wnmA:
28.1		 4ansA-5wnmA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_A_0LIA1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		5 / 5 VAL A  36
ILE A  81
TYR A  98
MET A  99
ILE A 159
 VX6  A 402 (-4.6A)
None
VX6  A 402 (-4.3A)
None
None
 0.32A 4c8bA-5wnmA:
31.2		 4c8bA-5wnmA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_A_0LIA1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		5 / 5 VAL A  36
ILE A 159
TYR A  98
MET A  99
ILE A 149
 VX6  A 402 (-4.6A)
None
VX6  A 402 (-4.3A)
None
None
 1.09A 4c8bA-5wnmA:
31.2		 4c8bA-5wnmA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		3 / 3 TYR A  98
MET A  99
ILE A  81
 VX6  A 402 (-4.3A)
None
None
 0.59A 4c8bB-5wnmA:
31.0		 4c8bB-5wnmA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		3 / 3 TYR A  98
MET A  99
ILE A 159
 VX6  A 402 (-4.3A)
None
None
 0.27A 4c8bB-5wnmA:
31.0		 4c8bB-5wnmA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CKJ_A_ADNA2014_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		6 / 10 GLY A  29
VAL A  36
ALA A  49
TYR A  98
SER A 103
LEU A 150
 VX6  A 402 ( 4.2A)
VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
VX6  A 402 (-4.3A)
VX6  A 402 ( 4.7A)
VX6  A 402 (-4.4A)
 0.55A 4ckjA-5wnmA:
28.7		 4ckjA-5wnmA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		3 / 3 TYR A 207
PHE A 223
ARG A 241
 None
 1.21A 4g19D-5wnmA:
undetectable		 4g19D-5wnmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I22_A_IREA9001_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		8 / 12 GLY A  29
VAL A  36
ALA A  49
LEU A  94
MET A  96
GLY A 102
LEU A 150
ASP A 161
 VX6  A 402 ( 4.2A)
VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
None
VX6  A 402 (-3.7A)
VX6  A 402 (-3.5A)
VX6  A 402 (-4.4A)
VX6  A 402 (-4.3A)
 0.85A 4i22A-5wnmA:
26.3		 4i22A-5wnmA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_C_TMQC202_1
(DIHYDROFOLATE
REDUCTASE)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		5 / 12 ILE A 211
ARG A 264
GLN A 263
LEU A 258
LEU A 217
 None
 0.97A 4m2xC-5wnmA:
undetectable		 4m2xC-5wnmA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QMN_A_DB8A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 24)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		6 / 12 ALA A  49
LYS A  51
GLU A  69
TYR A  98
LEU A 150
ASP A 161
 VX6  A 402 (-3.2A)
VX6  A 402 (-4.9A)
VX6  A 402 (-4.4A)
VX6  A 402 (-4.3A)
VX6  A 402 (-4.4A)
VX6  A 402 (-4.3A)
 0.69A 4qmnA-5wnmA:
26.4		 4qmnA-5wnmA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QMZ_A_B49A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 24)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		6 / 12 GLY A  29
VAL A  36
ALA A  49
MET A  96
TYR A  98
LEU A 150
 VX6  A 402 ( 4.2A)
VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
VX6  A 402 (-3.7A)
VX6  A 402 (-4.3A)
VX6  A 402 (-4.4A)
 0.60A 4qmzA-5wnmA:
26.7		 4qmzA-5wnmA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TYJ_A_0LIA801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		5 / 12 ALA A  49
GLU A  69
MET A  73
HIS A 141
LEU A 150
 VX6  A 402 (-3.2A)
VX6  A 402 (-4.4A)
None
None
VX6  A 402 (-4.4A)
 0.69A 4tyjA-5wnmA:
28.2		 4tyjA-5wnmA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U5J_A_RXTA601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		8 / 11 VAL A  36
ALA A  49
TYR A  98
MET A  99
GLY A 102
ASN A 148
LEU A 150
ASP A 161
 VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
VX6  A 402 (-4.3A)
None
VX6  A 402 (-3.5A)
None
VX6  A 402 (-4.4A)
VX6  A 402 (-4.3A)
 0.47A 4u5jA-5wnmA:
28.9		 4u5jA-5wnmA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U5J_B_RXTB601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		7 / 9 VAL A  36
ALA A  49
TYR A  98
MET A  99
GLY A 102
LEU A 150
ASP A 161
 VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
VX6  A 402 (-4.3A)
None
VX6  A 402 (-3.5A)
VX6  A 402 (-4.4A)
VX6  A 402 (-4.3A)
 0.72A 4u5jB-5wnmA:
28.0		 4u5jB-5wnmA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V01_B_0LIB1770_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		5 / 12 ALA A  49
GLU A  69
MET A  73
LEU A 132
HIS A 141
 VX6  A 402 (-3.2A)
VX6  A 402 (-4.4A)
None
None
None
 0.80A 4v01B-5wnmA:
27.8		 4v01B-5wnmA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_B_ANWB601_0
(RHODOPSIN KINASE)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		4 / 8 ALA A  49
MET A  96
LEU A 150
SER A 160
 VX6  A 402 (-3.2A)
VX6  A 402 (-3.7A)
VX6  A 402 (-4.4A)
VX6  A 402 (-3.3A)
 0.64A 4wboB-5wnmA:
21.5		 4wboB-5wnmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_C_ANWC601_0
(RHODOPSIN KINASE)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		4 / 6 ALA A  49
MET A  96
MET A  99
LEU A 150
 VX6  A 402 (-3.2A)
VX6  A 402 (-3.7A)
None
VX6  A 402 (-4.4A)
 0.56A 4wboC-5wnmA:
21.8		 4wboC-5wnmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XLI_A_1N1A601_1
(NON-SPECIFIC
PROTEIN-TYROSINE
KINASE)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		7 / 12 ALA A  49
GLU A  69
MET A  73
TYR A  98
MET A  99
GLY A 102
LEU A 150
 VX6  A 402 (-3.2A)
VX6  A 402 (-4.4A)
None
VX6  A 402 (-4.3A)
None
VX6  A 402 (-3.5A)
VX6  A 402 (-4.4A)
 0.61A 4xliA-5wnmA:
29.3		 4xliA-5wnmA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AAA_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		6 / 9 VAL A  36
ALA A  49
MET A  99
GLY A 102
LEU A 150
ASP A 161
 VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
None
VX6  A 402 (-3.5A)
VX6  A 402 (-4.4A)
VX6  A 402 (-4.3A)
 0.50A 5aaaA-5wnmA:
28.2		 5aaaA-5wnmA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AAC_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		6 / 10 VAL A  36
ALA A  49
MET A  99
GLY A 102
LEU A 150
ASP A 161
 VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
None
VX6  A 402 (-3.5A)
VX6  A 402 (-4.4A)
VX6  A 402 (-4.3A)
 0.53A 5aacA-5wnmA:
28.4		 5aacA-5wnmA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		3 / 3 GLU A 124
HIS A 156
ASP A 116
 None
 0.83A 5c0oG-5wnmA:
undetectable		 5c0oG-5wnmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I9X_A_DB8A1001_1
(EPHRIN TYPE-A
RECEPTOR 2)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		6 / 12 ALA A  49
LYS A  51
TYR A  98
GLY A 102
LEU A 150
SER A 160
 VX6  A 402 (-3.2A)
VX6  A 402 (-4.9A)
VX6  A 402 (-4.3A)
VX6  A 402 (-3.5A)
VX6  A 402 (-4.4A)
VX6  A 402 (-3.3A)
 0.68A 5i9xA-5wnmA:
28.4		 5i9xA-5wnmA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I9Y_A_1N1A1001_1
(EPHRIN TYPE-A
RECEPTOR 2)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		6 / 12 ALA A  49
MET A  73
TYR A  98
GLY A 102
LEU A 150
SER A 160
 VX6  A 402 (-3.2A)
None
VX6  A 402 (-4.3A)
VX6  A 402 (-3.5A)
VX6  A 402 (-4.4A)
VX6  A 402 (-3.3A)
 0.38A 5i9yA-5wnmA:
29.0		 5i9yA-5wnmA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_B_ADNB401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		5 / 9 GLY A  29
VAL A  36
ALA A  49
MET A  96
MET A  99
 VX6  A 402 ( 4.2A)
VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
VX6  A 402 (-3.7A)
None
 0.63A 5lw1B-5wnmA:
21.6		 5lw1B-5wnmA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_E_ADNE401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		5 / 10 GLY A  29
VAL A  36
ALA A  49
MET A  96
MET A  99
 VX6  A 402 ( 4.2A)
VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
VX6  A 402 (-3.7A)
None
 0.64A 5lw1E-5wnmA:
21.3		 5lw1E-5wnmA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_H_ADNH401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		5 / 9 GLY A  29
VAL A  36
ALA A  49
MET A  96
MET A  99
 VX6  A 402 ( 4.2A)
VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
VX6  A 402 (-3.7A)
None
 0.55A 5lw1H-5wnmA:
21.7		 5lw1H-5wnmA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OWR_A_1N1A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		4 / 8 ALA A  49
GLU A  69
LEU A 150
ASP A 161
 VX6  A 402 (-3.2A)
VX6  A 402 (-4.4A)
VX6  A 402 (-4.4A)
VX6  A 402 (-4.3A)
 0.55A 5owrA-5wnmA:
22.6		 5owrA-5wnmA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE0_A_XINA401_1
(AP2-ASSOCIATED
PROTEIN KINASE 1)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		6 / 12 GLU A  26
ALA A  49
GLU A  69
MET A  73
GLY A 102
LEU A 150
 None
VX6  A 402 (-3.2A)
VX6  A 402 (-4.4A)
None
VX6  A 402 (-3.5A)
VX6  A 402 (-4.4A)
 0.90A 5te0A-5wnmA:
24.2		 5te0A-5wnmA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC3_A_DB8A601_1
(WEE1-LIKE PROTEIN
KINASE)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		6 / 12 GLU A  26
ALA A  49
GLU A  69
TYR A  98
GLY A 102
ASP A 161
 None
VX6  A 402 (-3.2A)
VX6  A 402 (-4.4A)
VX6  A 402 (-4.3A)
VX6  A 402 (-3.5A)
VX6  A 402 (-4.3A)
 0.76A 5vc3A-5wnmA:
24.4		 5vc3A-5wnmA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC3_A_DB8A601_1
(WEE1-LIKE PROTEIN
KINASE)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		6 / 12 GLY A  29
ALA A  49
GLU A  69
TYR A  98
GLY A 102
ASP A 161
 VX6  A 402 ( 4.2A)
VX6  A 402 (-3.2A)
VX6  A 402 (-4.4A)
VX6  A 402 (-4.3A)
VX6  A 402 (-3.5A)
VX6  A 402 (-4.3A)
 0.80A 5vc3A-5wnmA:
24.4		 5vc3A-5wnmA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSD_A_1N1A901_0
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		9 / 12 VAL A  36
ALA A  49
LYS A  51
GLU A  69
MET A  73
TYR A  98
MET A  99
GLY A 102
LEU A 150
 VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
VX6  A 402 (-4.9A)
VX6  A 402 (-4.4A)
None
VX6  A 402 (-4.3A)
None
VX6  A 402 (-3.5A)
VX6  A 402 (-4.4A)
 0.87A 6bsdA-5wnmA:
25.8		 6bsdA-5wnmA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSD_A_1N1A901_0
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		8 / 12 VAL A  36
ALA A  49
LYS A  51
GLU A  69
TYR A  98
MET A  99
LEU A 150
ASP A 161
 VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
VX6  A 402 (-4.9A)
VX6  A 402 (-4.4A)
VX6  A 402 (-4.3A)
None
VX6  A 402 (-4.4A)
VX6  A 402 (-4.3A)
 1.45A 6bsdA-5wnmA:
25.8		 6bsdA-5wnmA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNM_A_1N1A1001_1
(-)		 5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4
(Mus
musculus) 		7 / 12 VAL A  36
ALA A  49
MET A  73
MET A  99
GLY A 102
LEU A 150
SER A 160
 VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
None
None
VX6  A 402 (-3.5A)
VX6  A 402 (-4.4A)
VX6  A 402 (-3.3A)
 0.81A 6fnmA-5wnmA:
28.3		 6fnmA-5wnmA:
13.80