SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wof'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TVX_B_PNXB902_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4A)		 5wof DYNEIN LIGHT CHAIN
1, PUTATIVE
(Plasmodium
falciparum) 		4 / 7 ASN A  66
ILE A  68
PHE A  70
PHE A  40
 None
 1.21A 3tvxB-5wofA:
undetectable		 3tvxB-5wofA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_A_032A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5wof DYNEIN LIGHT CHAIN
1, PUTATIVE
(Plasmodium
falciparum) 		4 / 5 ILE A  32
VAL A  52
PHE A  67
CYH A  18
 None
 1.32A 4rzvA-5wofA:
undetectable		 4rzvA-5wofA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_D_FK5D201_1
(FK506-BINDING
PROTEIN 1)		 5wof DYNEIN LIGHT CHAIN
1, PUTATIVE
(Plasmodium
falciparum) 		5 / 11 TYR A  44
ILE A  68
ILE A  13
ILE A  16
PHE A  40
 None
 1.23A 5hw8D-5wofA:
undetectable		 5hw8D-5wofA:
20.14