SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5woq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G70_A_SAMA2001_0 (PHENYLETHANOLAMINE N-METHYLTRANSFERASE)	5woq	TRANSCRIPTIONAL REGULATOR CLGR (Mycolicibacteriu m smegmatis)	5 / 12	ASP A 70 VAL A 67 ALA A 55 CYH A 57 VAL A 62	None	1.13A	2g70A-5woqA: undetectable	2g70A-5woqA: 19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G70_B_SAMB2002_0 (PHENYLETHANOLAMINE N-METHYLTRANSFERASE)	5woq	TRANSCRIPTIONAL REGULATOR CLGR (Mycolicibacteriu m smegmatis)	5 / 12	ASP A 70 VAL A 67 ALA A 55 CYH A 57 VAL A 62	None	1.14A	2g70B-5woqA: undetectable	2g70B-5woqA: 19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G72_A_SAMA2001_0 (PHENYLETHANOLAMINE N-METHYLTRANSFERASE)	5woq	TRANSCRIPTIONAL REGULATOR CLGR (Mycolicibacteriu m smegmatis)	5 / 12	ASP A 70 VAL A 67 ALA A 55 CYH A 57 VAL A 62	None	1.16A	2g72A-5woqA: undetectable	2g72A-5woqA: 19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G72_B_SAMB2002_0 (PHENYLETHANOLAMINE N-METHYLTRANSFERASE)	5woq	TRANSCRIPTIONAL REGULATOR CLGR (Mycolicibacteriu m smegmatis)	5 / 12	ILE A 9 VAL A 67 ALA A 55 CYH A 57 VAL A 62	None	1.18A	2g72B-5woqA: undetectable	2g72B-5woqA: 19.13

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2G70_A_SAMA2001_0","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","5woq","TRANSCRIPTIONAL REGULATOR CLGR","Mycolicibacterium smegmatis",5,"ASP A  70;VAL A  67;ALA A  55;CYH A  57;VAL A  62","None","1.13A","2g70A-5woqA:undetectable","2g70A-5woqA:19.13"],["2G70_B_SAMB2002_0","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","5woq","TRANSCRIPTIONAL REGULATOR CLGR","Mycolicibacterium smegmatis",5,"ASP A  70;VAL A  67;ALA A  55;CYH A  57;VAL A  62","None","1.14A","2g70B-5woqA:undetectable","2g70B-5woqA:19.13"],["2G72_A_SAMA2001_0","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","5woq","TRANSCRIPTIONAL REGULATOR CLGR","Mycolicibacterium smegmatis",5,"ASP A  70;VAL A  67;ALA A  55;CYH A  57;VAL A  62","None","1.16A","2g72A-5woqA:undetectable","2g72A-5woqA:19.13"],["2G72_B_SAMB2002_0","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","5woq","TRANSCRIPTIONAL REGULATOR CLGR","Mycolicibacterium smegmatis",5,"ILE A   9;VAL A  67;ALA A  55;CYH A  57;VAL A  62","None","1.18A","2g72B-5woqA:undetectable","2g72B-5woqA:19.13"]]