SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wos'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_D_IMND476_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 5wos BCL-2-LIKE PROTEIN
11
CNPV058 BCL-2 LIKE
PROTEIN
(Canarypox
virus;
Homo
sapiens) 		5 / 12 ILE A  81
SER A  92
ILE A  94
VAL A  77
LEU B  62
 None
 0.94A 1z9hD-5wosA:
undetectable		 1z9hD-5wosA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		 5wos CNPV058 BCL-2 LIKE
PROTEIN
(Canarypox
virus) 		4 / 6 ILE A 119
SER A 123
ILE A  94
PHE A  22
 None
 1.16A 2q72A-5wosA:
undetectable		 2q72A-5wosA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)		 5wos CNPV058 BCL-2 LIKE
PROTEIN
(Canarypox
virus) 		4 / 6 ASP A  49
ASP A  37
ASN A  32
GLU A  24
 None
 1.32A 3vywA-5wosA:
undetectable		 3vywA-5wosA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_1
(MNMC2)		 5wos CNPV058 BCL-2 LIKE
PROTEIN
(Canarypox
virus) 		4 / 5 ASP A  49
ASP A  37
ASN A  32
GLU A  24
 None
 1.30A 3vywD-5wosA:
undetectable		 3vywD-5wosA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7B_C_ACTC513_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5wos CNPV058 BCL-2 LIKE
PROTEIN
(Canarypox
virus) 		3 / 3 TYR A  78
HIS A  82
ARG A 127
 None
 0.91A 4e7bC-5wosA:
undetectable		 4e7bC-5wosA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_0
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 5wos CNPV058 BCL-2 LIKE
PROTEIN
BCL-2-LIKE PROTEIN
11
(Canarypox
virus;
Homo
sapiens) 		5 / 12 ILE A  81
GLY B  66
ILE B  65
ILE A  18
ALA A  98
 None
 1.02A 5e72A-5wosA:
undetectable		 5e72A-5wosA:
20.07