SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wou'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJ2_A_SAMA2201_1 (PROTEIN (METHIONINE REPRESSOR))	5wou	PROTEIN LAP4 (Drosophila melanogaster)	4 / 4	HIS A 71 ALA A 21 PHE A 37 GLY A 23	EDO A 105 (-4.1A) None None EDO A 103 (-3.7A)	1.21A	1mj2B-5wouA: undetectable	1mj2B-5wouA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJ2_C_SAMC1200_1 (PROTEIN (METHIONINE REPRESSOR))	5wou	PROTEIN LAP4 (Drosophila melanogaster)	4 / 4	HIS A 71 ALA A 21 PHE A 37 GLY A 23	EDO A 105 (-4.1A) None None EDO A 103 (-3.7A)	1.21A	1mj2D-5wouA: undetectable	1mj2D-5wouA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJO_A_SAMA199_1 (METHIONINE REPRESSOR)	5wou	PROTEIN LAP4 (Drosophila melanogaster)	4 / 4	HIS A 71 ALA A 21 PHE A 37 GLY A 23	EDO A 105 (-4.1A) None None EDO A 103 (-3.7A)	1.20A	1mjoB-5wouA: undetectable	1mjoB-5wouA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJO_B_SAMB200_0 (METHIONINE REPRESSOR)	5wou	PROTEIN LAP4 (Drosophila melanogaster)	4 / 4	HIS A 71 ALA A 21 PHE A 37 GLY A 23	EDO A 105 (-4.1A) None None EDO A 103 (-3.7A)	1.22A	1mjoA-5wouA: undetectable	1mjoA-5wouA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJO_D_SAMD200_1 (METHIONINE REPRESSOR)	5wou	PROTEIN LAP4 (Drosophila melanogaster)	4 / 4	HIS A 71 ALA A 21 PHE A 37 GLY A 23	EDO A 105 (-4.1A) None None EDO A 103 (-3.7A)	1.21A	1mjoD-5wouA: undetectable	1mjoD-5wouA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QHF_A_NCAA493_0 (CHORISMATE SYNTHASE)	5wou	PROTEIN LAP4 (Drosophila melanogaster)	5 / 11	ILE A 38 ILE A 7 ALA A 50 ALA A 47 VAL A 41	None	1.08A	2qhfA-5wouA: undetectable	2qhfA-5wouA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_A_UEGA300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	5wou	PROTEIN LAP4 (Drosophila melanogaster)	5 / 11	GLY A 17 ASP A 48 ALA A 44 GLY A 45 VAL A 41	None	1.24A	4c5lA-5wouA: undetectable	4c5lA-5wouA: 15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_B_PXLB300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	5wou	PROTEIN LAP4 (Drosophila melanogaster)	5 / 9	GLY A 17 ASP A 48 ALA A 44 GLY A 45 VAL A 41	None	1.27A	4c5lB-5wouA: undetectable	4c5lB-5wouA: 15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_C_UEGC300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	5wou	PROTEIN LAP4 (Drosophila melanogaster)	5 / 10	GLY A 17 ASP A 48 ALA A 44 GLY A 45 VAL A 41	None	1.26A	4c5lC-5wouA: undetectable	4c5lC-5wouA: 15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	5wou	PROTEIN LAP4 (Drosophila melanogaster)	5 / 10	GLY A 17 ASP A 48 ALA A 44 GLY A 45 VAL A 41	None	1.25A	4c5lD-5wouA: undetectable	4c5lD-5wouA: 15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5N_B_PXLB300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	5wou	PROTEIN LAP4 (Drosophila melanogaster)	5 / 10	GLY A 17 ASP A 48 ALA A 44 GLY A 45 VAL A 41	None	1.26A	4c5nB-5wouA: undetectable	4c5nB-5wouA: 15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5N_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	5wou	PROTEIN LAP4 (Drosophila melanogaster)	5 / 10	GLY A 17 ASP A 48 ALA A 44 GLY A 45 VAL A 41	None	1.22A	4c5nD-5wouA: undetectable	4c5nD-5wouA: 15.58

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1MJ2_A_SAMA2201_1","PROTEIN (METHIONINE REPRESSOR)","5wou","PROTEIN LAP4","Drosophila melanogaster",4,"HIS A  71;ALA A  21;PHE A  37;GLY A  23","EDO A 105 (-4.1A);None;None;EDO A 103 (-3.7A)","1.21A","1mj2B-5wouA:undetectable","1mj2B-5wouA:undetectable"],["1MJ2_C_SAMC1200_1","PROTEIN (METHIONINE REPRESSOR)","5wou","PROTEIN LAP4","Drosophila melanogaster",4,"HIS A  71;ALA A  21;PHE A  37;GLY A  23","EDO A 105 (-4.1A);None;None;EDO A 103 (-3.7A)","1.21A","1mj2D-5wouA:undetectable","1mj2D-5wouA:undetectable"],["1MJO_A_SAMA199_1","METHIONINE REPRESSOR","5wou","PROTEIN LAP4","Drosophila melanogaster",4,"HIS A  71;ALA A  21;PHE A  37;GLY A  23","EDO A 105 (-4.1A);None;None;EDO A 103 (-3.7A)","1.20A","1mjoB-5wouA:undetectable","1mjoB-5wouA:undetectable"],["1MJO_B_SAMB200_0","METHIONINE REPRESSOR","5wou","PROTEIN LAP4","Drosophila melanogaster",4,"HIS A  71;ALA A  21;PHE A  37;GLY A  23","EDO A 105 (-4.1A);None;None;EDO A 103 (-3.7A)","1.22A","1mjoA-5wouA:undetectable","1mjoA-5wouA:undetectable"],["1MJO_D_SAMD200_1","METHIONINE REPRESSOR","5wou","PROTEIN LAP4","Drosophila melanogaster",4,"HIS A  71;ALA A  21;PHE A  37;GLY A  23","EDO A 105 (-4.1A);None;None;EDO A 103 (-3.7A)","1.21A","1mjoD-5wouA:undetectable","1mjoD-5wouA:undetectable"],["2QHF_A_NCAA493_0","CHORISMATE SYNTHASE","5wou","PROTEIN LAP4","Drosophila melanogaster",5,"ILE A  38;ILE A   7;ALA A  50;ALA A  47;VAL A  41","None","1.08A","2qhfA-5wouA:undetectable","2qhfA-5wouA:undetectable"],["4C5L_A_UEGA300_1","PHOSPHOMETHYLPYRIMIDINE KINASE","5wou","PROTEIN LAP4","Drosophila melanogaster",5,"GLY A  17;ASP A  48;ALA A  44;GLY A  45;VAL A  41","None","1.24A","4c5lA-5wouA:undetectable","4c5lA-5wouA:15.58"],["4C5L_B_PXLB300_1","PHOSPHOMETHYLPYRIMIDINE KINASE","5wou","PROTEIN LAP4","Drosophila melanogaster",5,"GLY A  17;ASP A  48;ALA A  44;GLY A  45;VAL A  41","None","1.27A","4c5lB-5wouA:undetectable","4c5lB-5wouA:15.58"],["4C5L_C_UEGC300_1","PHOSPHOMETHYLPYRIMIDINE KINASE","5wou","PROTEIN LAP4","Drosophila melanogaster",5,"GLY A  17;ASP A  48;ALA A  44;GLY A  45;VAL A  41","None","1.26A","4c5lC-5wouA:undetectable","4c5lC-5wouA:15.58"],["4C5L_D_UEGD300_1","PHOSPHOMETHYLPYRIMIDINE KINASE","5wou","PROTEIN LAP4","Drosophila melanogaster",5,"GLY A  17;ASP A  48;ALA A  44;GLY A  45;VAL A  41","None","1.25A","4c5lD-5wouA:undetectable","4c5lD-5wouA:15.58"],["4C5N_B_PXLB300_1","PHOSPHOMETHYLPYRIMIDINE KINASE","5wou","PROTEIN LAP4","Drosophila melanogaster",5,"GLY A  17;ASP A  48;ALA A  44;GLY A  45;VAL A  41","None","1.26A","4c5nB-5wouA:undetectable","4c5nB-5wouA:15.58"],["4C5N_D_UEGD300_1","PHOSPHOMETHYLPYRIMIDINE KINASE","5wou","PROTEIN LAP4","Drosophila melanogaster",5,"GLY A  17;ASP A  48;ALA A  44;GLY A  45;VAL A  41","None","1.22A","4c5nD-5wouA:undetectable","4c5nD-5wouA:15.58"]]