SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wox'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1AV2_B_DVAB8_0 (GRAMICIDIN A)	5wox	UNCHARACTERIZED PROTEIN (Mycolicibacteriu m smegmatis)	3 / 3	VAL A 79 VAL A 94 TRP A 92	None	0.46A	1av2A-5woxA: undetectable 1av2B-5woxA: undetectable	1av2A-5woxA: undetectable 1av2B-5woxA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1W5U_B_DVAB8_0 (GRAMICIDIN D)	5wox	UNCHARACTERIZED PROTEIN (Mycolicibacteriu m smegmatis)	3 / 3	VAL A 79 VAL A 94 TRP A 92	None	0.64A	1w5uA-5woxA: undetectable 1w5uB-5woxA: undetectable	1w5uA-5woxA: undetectable 1w5uB-5woxA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IZQ_C_DVAC8_0 (GRAMICIDIN D)	5wox	UNCHARACTERIZED PROTEIN (Mycolicibacteriu m smegmatis)	3 / 3	VAL A 94 TRP A 92 VAL A 79	None	0.54A	2izqC-5woxA: undetectable 2izqD-5woxA: undetectable	2izqC-5woxA: undetectable 2izqD-5woxA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A97_C_ZPCC1318_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	5wox	UNCHARACTERIZED PROTEIN (Mycolicibacteriu m smegmatis)	5 / 12	VAL A 103 ILE A 12 GLU A 81 ILE A 131 VAL A 143	None	1.09A	4a97B-5woxA: undetectable 4a97C-5woxA: undetectable	4a97B-5woxA: 13.03 4a97C-5woxA: 13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HW4_A_SAMA801_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I)	5wox	UNCHARACTERIZED PROTEIN (Mycolicibacteriu m smegmatis)	5 / 12	GLY A 47 ASP A 25 ALA A 54 TYR A 41 LEU A 44	None	1.23A	5hw4A-5woxA: undetectable	5hw4A-5woxA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HW4_B_SAMB801_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I)	5wox	UNCHARACTERIZED PROTEIN (Mycolicibacteriu m smegmatis)	5 / 11	GLY A 47 ASP A 25 ALA A 54 TYR A 41 LEU A 44	None	1.22A	5hw4B-5woxA: undetectable	5hw4B-5woxA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HW4_C_SAMC801_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I)	5wox	UNCHARACTERIZED PROTEIN (Mycolicibacteriu m smegmatis)	5 / 12	GLY A 47 ASP A 25 ALA A 54 TYR A 41 LEU A 44	None	1.22A	5hw4C-5woxA: undetectable	5hw4C-5woxA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LF7_Y_6V8Y306_0 (PROTEASOME SUBUNIT BETA TYPE-1 PROTEASOME SUBUNIT BETA TYPE-5)	5wox	UNCHARACTERIZED PROTEIN (Mycolicibacteriu m smegmatis)	5 / 11	THR A 71 ALA A 70 VAL A 74 GLY A 46 GLY A 47	None	0.96A	5lf7Y-5woxA: undetectable 5lf7Z-5woxA: undetectable	5lf7Y-5woxA: undetectable 5lf7Z-5woxA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1AV2_B_DVAB8_0","GRAMICIDIN A","5wox","UNCHARACTERIZED PROTEIN","Mycolicibacterium smegmatis",3,"VAL A  79;VAL A  94;TRP A  92","None","0.46A","1av2A-5woxA:undetectable;1av2B-5woxA:undetectable","1av2A-5woxA:undetectable;1av2B-5woxA:undetectable"],["1W5U_B_DVAB8_0","GRAMICIDIN D","5wox","UNCHARACTERIZED PROTEIN","Mycolicibacterium smegmatis",3,"VAL A  79;VAL A  94;TRP A  92","None","0.64A","1w5uA-5woxA:undetectable;1w5uB-5woxA:undetectable","1w5uA-5woxA:undetectable;1w5uB-5woxA:undetectable"],["2IZQ_C_DVAC8_0","GRAMICIDIN D","5wox","UNCHARACTERIZED PROTEIN","Mycolicibacterium smegmatis",3,"VAL A  94;TRP A  92;VAL A  79","None","0.54A","2izqC-5woxA:undetectable;2izqD-5woxA:undetectable","2izqC-5woxA:undetectable;2izqD-5woxA:undetectable"],["4A97_C_ZPCC1318_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","5wox","UNCHARACTERIZED PROTEIN","Mycolicibacterium smegmatis",5,"VAL A 103;ILE A  12;GLU A  81;ILE A 131;VAL A 143","None","1.09A","4a97B-5woxA:undetectable;4a97C-5woxA:undetectable","4a97B-5woxA:13.03;4a97C-5woxA:13.03"],["5HW4_A_SAMA801_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I","5wox","UNCHARACTERIZED PROTEIN","Mycolicibacterium smegmatis",5,"GLY A  47;ASP A  25;ALA A  54;TYR A  41;LEU A  44","None","1.23A","5hw4A-5woxA:undetectable","5hw4A-5woxA:undetectable"],["5HW4_B_SAMB801_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I","5wox","UNCHARACTERIZED PROTEIN","Mycolicibacterium smegmatis",5,"GLY A  47;ASP A  25;ALA A  54;TYR A  41;LEU A  44","None","1.22A","5hw4B-5woxA:undetectable","5hw4B-5woxA:undetectable"],["5HW4_C_SAMC801_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I","5wox","UNCHARACTERIZED PROTEIN","Mycolicibacterium smegmatis",5,"GLY A  47;ASP A  25;ALA A  54;TYR A  41;LEU A  44","None","1.22A","5hw4C-5woxA:undetectable","5hw4C-5woxA:undetectable"],["5LF7_Y_6V8Y306_0","PROTEASOME SUBUNIT BETA TYPE-1;PROTEASOME SUBUNIT BETA TYPE-5","5wox","UNCHARACTERIZED PROTEIN","Mycolicibacterium smegmatis",5,"THR A  71;ALA A  70;VAL A  74;GLY A  46;GLY A  47","None","0.96A","5lf7Y-5woxA:undetectable;5lf7Z-5woxA:undetectable","5lf7Y-5woxA:undetectable;5lf7Z-5woxA:undetectable"]]