SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5woy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PHG_A_MYTA422_1
(CYTOCHROME P450-CAM)		 5woy PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Caldanaerobacter
subterraneus) 		5 / 11 LEU A 130
VAL A 133
GLY A 134
VAL A  89
ILE A  86
 None
 1.16A 1phgA-5woyA:
undetectable		 1phgA-5woyA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 5woy PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Caldanaerobacter
subterraneus) 		5 / 9 LEU A 130
VAL A 133
GLY A 134
VAL A  89
ILE A  86
 None
 1.19A 2a1oB-5woyA:
undetectable		 2a1oB-5woyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5woy PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Caldanaerobacter
subterraneus) 		4 / 6 THR A  20
VAL A 147
LEU A 149
ALA A 160
 None
 1.08A 2e1qA-5woyA:
undetectable		 2e1qA-5woyA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 5woy PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Caldanaerobacter
subterraneus) 		5 / 10 ILE A 137
THR A  50
VAL A 104
ILE A  86
SER A  81
 None
 1.36A 3kpbD-5woyA:
undetectable		 3kpbD-5woyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 5woy PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Caldanaerobacter
subterraneus) 		4 / 6 VAL A 203
VAL A 176
ILE A 159
ARG A 186
 None
 1.02A 3ms9A-5woyA:
undetectable		 3ms9A-5woyA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 5woy PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Caldanaerobacter
subterraneus) 		4 / 6 VAL A 203
VAL A 176
ILE A 159
ARG A 186
 None
 1.09A 3mssA-5woyA:
undetectable		 3mssA-5woyA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_C_STIC1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 5woy PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Caldanaerobacter
subterraneus) 		4 / 6 VAL A 203
VAL A 176
ILE A 159
ARG A 186
 None
 1.10A 3mssC-5woyA:
undetectable		 3mssC-5woyA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_A_CAMA1419_0
(CYTOCHROME P450)		 5woy PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Caldanaerobacter
subterraneus) 		5 / 12 THR A 181
GLY A 185
THR A 187
VAL A   5
VAL A 203
 None
 1.06A 4c9lA-5woyA:
undetectable		 4c9lA-5woyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_A_CAMA423_0
(CYTOCHROME P450)		 5woy PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Caldanaerobacter
subterraneus) 		5 / 12 THR A 181
GLY A 185
THR A 187
VAL A   5
VAL A 203
 None
 1.04A 4c9oA-5woyA:
undetectable		 4c9oA-5woyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_B_CAMB423_0
(CYTOCHROME P450)		 5woy PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Caldanaerobacter
subterraneus) 		5 / 12 THR A 181
GLY A 185
THR A 187
VAL A   5
VAL A 203
 None
 1.04A 4c9oB-5woyA:
undetectable		 4c9oB-5woyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_B_SAMB601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 5woy PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Caldanaerobacter
subterraneus) 		5 / 12 SER A  81
GLN A  51
ILE A 108
VAL A  89
VAL A 107
 None
 1.12A 5dpdB-5woyA:
4.0		 5dpdB-5woyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5woy PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Caldanaerobacter
subterraneus) 		4 / 5 LEU A 123
LYS A 124
ALA A 127
LEU A 130
 None
 0.84A 5vkqA-5woyA:
3.3
5vkqD-5woyA:
3.3		 5vkqA-5woyA:
undetectable
5vkqD-5woyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5woy PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Caldanaerobacter
subterraneus) 		4 / 5 LEU A 123
LYS A 124
ALA A 127
LEU A 130
 None
 0.83A 5vkqA-5woyA:
3.3
5vkqB-5woyA:
3.3		 5vkqA-5woyA:
undetectable
5vkqB-5woyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5woy PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Caldanaerobacter
subterraneus) 		4 / 5 LEU A 123
LYS A 124
ALA A 127
LEU A 130
 None
 0.83A 5vkqB-5woyA:
3.3
5vkqC-5woyA:
3.3		 5vkqB-5woyA:
undetectable
5vkqC-5woyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5woy PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Caldanaerobacter
subterraneus) 		4 / 5 LEU A 123
LYS A 124
ALA A 127
LEU A 130
 None
 0.83A 5vkqC-5woyA:
3.3
5vkqD-5woyA:
3.3		 5vkqC-5woyA:
undetectable
5vkqD-5woyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11803_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
EL18)		 5woy PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Caldanaerobacter
subterraneus) 		3 / 3 SER A 241
LYS A 242
SER A 245
 None
 0.82A 6az3P-5woyA:
undetectable		 6az3P-5woyA:
24.71