SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wp0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KW0_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 5wp0 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Aliivibrio
fischeri) 		5 / 12 VAL A 201
LEU A 193
LEU A 244
THR A  52
GLU A 171
 None
 1.37A 1kw0A-5wp0A:
undetectable		 1kw0A-5wp0A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_B_DVAB35_0
(UBIQUITIN)		 5wp0 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Aliivibrio
fischeri) 		4 / 6 LEU A  40
GLN A  58
ILE A  98
PRO A 100
 None
 0.86A 2fcnA-5wp0A:
undetectable
2fcnB-5wp0A:
undetectable		 2fcnA-5wp0A:
11.72
2fcnB-5wp0A:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CV9_A_VDXA501_1
(CYTOCHROME P450-SU1)		 5wp0 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Aliivibrio
fischeri) 		5 / 9 VAL A  78
SER A 105
ARG A  79
ILE A  98
GLY A 161
 None
 1.07A 3cv9A-5wp0A:
undetectable		 3cv9A-5wp0A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3006_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5wp0 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Aliivibrio
fischeri) 		4 / 6 ASN A 194
ILE A  15
GLU A 245
LYS A  12
 None
 1.34A 3kp6A-5wp0A:
undetectable
3kp6B-5wp0A:
undetectable		 3kp6A-5wp0A:
19.78
3kp6B-5wp0A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_B_RGZB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 5wp0 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Aliivibrio
fischeri) 		5 / 12 PRO A 189
LEU A 164
LEU A  40
CYH A  37
ILE A  28
 None
 1.10A 4a7aB-5wp0A:
undetectable		 4a7aB-5wp0A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)		 5wp0 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Aliivibrio
fischeri) 		4 / 6 ASN A 194
ALA A 170
THR A 174
LEU A 257
 None
 0.98A 4ejgD-5wp0A:
undetectable		 4ejgD-5wp0A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_1
(METHYLTRANSFERASE
MPPJ)		 5wp0 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Aliivibrio
fischeri) 		3 / 3 ARG A  24
ASP A  49
ASP A 182
 None
 0.84A 4kicB-5wp0A:
undetectable		 4kicB-5wp0A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 5wp0 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Aliivibrio
fischeri) 		4 / 7 HIS A 120
ASN A 119
HIS A 116
VAL A 139
 None
 0.75A 4p6sA-5wp0A:
undetectable		 4p6sA-5wp0A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 5wp0 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Aliivibrio
fischeri) 		4 / 7 HIS A 120
ASN A 119
HIS A 116
VAL A 139
 None
 0.77A 4p6sB-5wp0A:
undetectable		 4p6sB-5wp0A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 5wp0 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Aliivibrio
fischeri) 		4 / 7 HIS A 120
ASN A 119
HIS A 116
VAL A 139
 None
 0.77A 5i3aA-5wp0A:
undetectable		 5i3aA-5wp0A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 5wp0 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Aliivibrio
fischeri) 		4 / 7 HIS A 120
ASN A 119
HIS A 116
VAL A 139
 None
 0.75A 5i3aB-5wp0A:
undetectable		 5i3aB-5wp0A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 5wp0 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Aliivibrio
fischeri) 		4 / 7 HIS A 120
ASN A 119
HIS A 116
VAL A 139
 None
 0.77A 5i3bA-5wp0A:
undetectable		 5i3bA-5wp0A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5wp0 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Aliivibrio
fischeri) 		4 / 7 HIS A 120
ASN A 119
HIS A 116
VAL A 139
 None
 0.74A 5m8rA-5wp0A:
undetectable		 5m8rA-5wp0A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5wp0 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Aliivibrio
fischeri) 		4 / 8 HIS A 120
ASN A 119
HIS A 116
VAL A 139
 None
 0.71A 5m8rB-5wp0A:
undetectable		 5m8rB-5wp0A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5wp0 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Aliivibrio
fischeri) 		4 / 8 HIS A 120
ASN A 119
HIS A 116
VAL A 139
 None
 0.74A 5m8rD-5wp0A:
undetectable		 5m8rD-5wp0A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_0
(HIV-1 PROTEASE)		 5wp0 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Aliivibrio
fischeri) 		5 / 10 ALA A 151
VAL A  78
ILE A  41
GLY A 157
ILE A 106
 None
 1.01A 6dj2A-5wp0A:
undetectable		 6dj2A-5wp0A:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 5wp0 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Aliivibrio
fischeri) 		4 / 6 VAL A  78
ASN A 107
PRO A  81
ILE A 108
 None
 1.19A 6h7uA-5wp0A:
undetectable		 6h7uA-5wp0A:
19.10