SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wpn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWM_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 5wpn FERRITIN
(Chaetopterus
variopedatus) 		3 / 3 SER A  33
GLU A  86
ASP A  88
 None
 0.82A 3bwmA-5wpnA:
undetectable		 3bwmA-5wpnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWY_A_SAMA301_1
(COMT PROTEIN)		 5wpn FERRITIN
(Chaetopterus
variopedatus) 		3 / 3 SER A  33
GLU A  86
ASP A  88
 None
 0.84A 3bwyA-5wpnA:
undetectable		 3bwyA-5wpnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 5wpn FERRITIN
(Chaetopterus
variopedatus) 		3 / 3 SER A  33
GLU A  86
ASP A  88
 None
 0.79A 4xudA-5wpnA:
undetectable		 4xudA-5wpnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_A_ASCA1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 5wpn FERRITIN
(Chaetopterus
variopedatus) 		4 / 6 HIS A 115
TYR A  69
ARG A  73
HIS A 125
 ZN  A 205 ( 3.2A)
None
None
None
 1.35A 5kkzA-5wpnA:
undetectable
5kkzG-5wpnA:
undetectable		 5kkzA-5wpnA:
undetectable
5kkzG-5wpnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_E_ASCE1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 5wpn FERRITIN
(Chaetopterus
variopedatus) 		4 / 7 ILE A  17
VAL A  13
TYR A   9
ARG A  73
 None
 1.09A 5kkzC-5wpnA:
undetectable
5kkzE-5wpnA:
0.0		 5kkzC-5wpnA:
undetectable
5kkzE-5wpnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_K_ASCK1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 5wpn FERRITIN
(Chaetopterus
variopedatus) 		4 / 7 ILE A  17
VAL A  13
TYR A   9
ARG A  73
 None
 1.10A 5kkzK-5wpnA:
2.1
5kkzQ-5wpnA:
undetectable		 5kkzK-5wpnA:
undetectable
5kkzQ-5wpnA:
undetectable