SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wpw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_0
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5wpw 11S GLOBULIN ISOFORM
1
(Cocos
nucifera) 		5 / 12 SER A  97
SER A  82
MET A 328
ILE A 405
LEU A 191
 None
 1.44A 3aocC-5wpwA:
undetectable		 3aocC-5wpwA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_2
(PHOSPHOLIPASE A2)		 5wpw 11S GLOBULIN ISOFORM
1
(Cocos
nucifera) 		4 / 6 VAL A 333
VAL A 334
ARG A 311
ARG A 337
 None
 1.09A 3bjwF-5wpwA:
undetectable		 3bjwF-5wpwA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_1
(CYTOCHROME P450 2R1)		 5wpw 11S GLOBULIN ISOFORM
1
(Cocos
nucifera) 		4 / 5 ASN A 306
ALA A 395
LEU A 402
THR A 415
 None
 0.95A 3dl9A-5wpwA:
undetectable		 3dl9A-5wpwA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 5wpw 11S GLOBULIN ISOFORM
1
(Cocos
nucifera) 		4 / 8 MET A 328
SER A 408
SER A 317
LEU A 323
 None
 1.06A 3lsfH-5wpwA:
undetectable		 3lsfH-5wpwA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_F_SAMF228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 5wpw 11S GLOBULIN ISOFORM
1
(Cocos
nucifera) 		5 / 12 GLY A 202
ALA A 201
SER A  97
ASP A 249
GLN A 204
 None
 1.33A 3nmuA-5wpwA:
undetectable
3nmuF-5wpwA:
undetectable		 3nmuA-5wpwA:
21.66
3nmuF-5wpwA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 5wpw 11S GLOBULIN ISOFORM
1
(Cocos
nucifera) 		5 / 12 THR A  58
GLN A 204
ARG A  60
GLY A 252
ASN A 170
 None
 1.25A 3v3oA-5wpwA:
undetectable		 3v3oA-5wpwA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 5wpw 11S GLOBULIN ISOFORM
1
(Cocos
nucifera) 		5 / 11 GLN A 109
GLY A 110
ALA A  63
GLY A  64
GLU A  62
 None
 1.15A 4a6nA-5wpwA:
undetectable		 4a6nA-5wpwA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_A_UEGA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5wpw 11S GLOBULIN ISOFORM
1
(Cocos
nucifera) 		5 / 11 GLY A 252
ALA A 201
GLY A 202
VAL A 255
CYH A 246
 None
 1.24A 4c5lA-5wpwA:
undetectable		 4c5lA-5wpwA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5wpw 11S GLOBULIN ISOFORM
1
(Cocos
nucifera) 		5 / 9 GLY A 252
ALA A 201
GLY A 202
VAL A 255
CYH A 246
 None
 1.23A 4c5lB-5wpwA:
undetectable		 4c5lB-5wpwA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_C_UEGC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5wpw 11S GLOBULIN ISOFORM
1
(Cocos
nucifera) 		5 / 10 GLY A 252
ALA A 201
GLY A 202
VAL A 255
CYH A 246
 None
 1.29A 4c5lC-5wpwA:
undetectable		 4c5lC-5wpwA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5wpw 11S GLOBULIN ISOFORM
1
(Cocos
nucifera) 		5 / 10 GLY A 252
ALA A 201
GLY A 202
VAL A 255
CYH A 246
 None
 1.24A 4c5lD-5wpwA:
undetectable		 4c5lD-5wpwA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5wpw 11S GLOBULIN ISOFORM
1
(Cocos
nucifera) 		5 / 10 GLY A 252
ALA A 201
GLY A 202
VAL A 255
CYH A 246
 None
 1.25A 4c5nB-5wpwA:
undetectable		 4c5nB-5wpwA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5wpw 11S GLOBULIN ISOFORM
1
(Cocos
nucifera) 		5 / 10 GLY A 252
ALA A 201
GLY A 202
VAL A 255
CYH A 246
 None
 1.21A 4c5nD-5wpwA:
undetectable		 4c5nD-5wpwA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2D_F_LFXF102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 5wpw 11S GLOBULIN ISOFORM
1
(Cocos
nucifera) 		3 / 4 ARG A 359
GLY A 396
GLU A 398
 None
 0.54A 4z2dB-5wpwA:
undetectable
4z2dC-5wpwA:
undetectable		 4z2dB-5wpwA:
23.54
4z2dC-5wpwA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_F_TR6F101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 5wpw 11S GLOBULIN ISOFORM
1
(Cocos
nucifera) 		4 / 5 GLY A 360
ARG A 359
GLY A 396
GLU A 398
 None
 1.00A 4z2eB-5wpwA:
undetectable
4z2eC-5wpwA:
undetectable		 4z2eB-5wpwA:
23.54
4z2eC-5wpwA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_F_TR6F101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 5wpw 11S GLOBULIN ISOFORM
1
(Cocos
nucifera) 		4 / 5 GLY A 360
ARG A 359
GLY A 399
GLU A 398
 None
 1.21A 4z2eB-5wpwA:
undetectable
4z2eC-5wpwA:
undetectable		 4z2eB-5wpwA:
23.54
4z2eC-5wpwA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)		 5wpw 11S GLOBULIN ISOFORM
1
(Cocos
nucifera) 		3 / 3 HIS A 146
LYS A 148
PHE A 125
 None
 1.35A 5klaA-5wpwA:
undetectable		 5klaA-5wpwA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_D_CCSD14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2
PROGRAMMED CELL
DEATH 1 LIGAND 1)		 5wpw 11S GLOBULIN ISOFORM
1
(Cocos
nucifera) 		5 / 12 LEU A 335
ARG A 359
GLY A 396
GLU A 376
GLY A 360
 None
 1.20A 5o4yD-5wpwA:
undetectable
5o4yE-5wpwA:
undetectable		 5o4yD-5wpwA:
4.59
5o4yE-5wpwA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA411_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5wpw 11S GLOBULIN ISOFORM
1
(Cocos
nucifera) 		3 / 3 LYS A 446
LEU A 447
ARG A 443
 None
 0.66A 5yw0A-5wpwA:
3.1		 5yw0A-5wpwA:
22.92