SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wq0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PCG_B_ESTB2_1 (ESTROGEN RECEPTOR)	5wq0	STAGE 0 SPORULATION PROTEIN (Paenisporosarcin a sp. TG-14)	5 / 10	MET B 71 LEU B 68 ALA B 66 MET B 59 LEU B 42	None	1.38A	1pcgB-5wq0B: undetectable	1pcgB-5wq0B: 23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S9P_A_DESA459_1 (ESTROGEN-RELATED RECEPTOR GAMMA)	5wq0	STAGE 0 SPORULATION PROTEIN (Paenisporosarcin a sp. TG-14)	5 / 12	LEU B 15 ALA B 9 LEU B 53 VAL B 6 LEU B 115	None	1.03A	1s9pA-5wq0B: undetectable	1s9pA-5wq0B: 22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S9P_B_DESB459_1 (ESTROGEN-RELATED RECEPTOR GAMMA)	5wq0	STAGE 0 SPORULATION PROTEIN (Paenisporosarcin a sp. TG-14)	5 / 12	LEU B 15 ALA B 9 LEU B 53 VAL B 6 LEU B 115	None	1.05A	1s9pB-5wq0B: undetectable	1s9pB-5wq0B: 22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S9P_D_DESD600_1 (ESTROGEN-RELATED RECEPTOR GAMMA)	5wq0	STAGE 0 SPORULATION PROTEIN (Paenisporosarcin a sp. TG-14)	5 / 12	LEU B 15 ALA B 9 LEU B 53 VAL B 6 LEU B 115	None	1.00A	1s9pD-5wq0B: undetectable	1s9pD-5wq0B: 22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OCF_A_ESTA596_1 (ESTROGEN RECEPTOR)	5wq0	STAGE 0 SPORULATION PROTEIN (Paenisporosarcin a sp. TG-14)	5 / 10	MET B 71 LEU B 68 ALA B 66 MET B 59 LEU B 42	None	1.39A	2ocfA-5wq0B: undetectable	2ocfA-5wq0B: 17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XT8_A_TMQA302_1 (RV2671)	5wq0	STAGE 0 SPORULATION PROTEIN (Paenisporosarcin a sp. TG-14)	5 / 12	ILE B 4 GLY B 124 ALA B 123 ASP B 51 GLU B 2	None	1.31A	4xt8A-5wq0B: undetectable	4xt8A-5wq0B: 17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DXB_A_ESTA1000_1 (ESTROGEN RECEPTOR)	5wq0	STAGE 0 SPORULATION PROTEIN (Paenisporosarcin a sp. TG-14)	5 / 10	MET B 71 LEU B 68 ALA B 66 MET B 59 LEU B 42	None	1.40A	5dxbA-5wq0B: undetectable	5dxbA-5wq0B: 23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DXE_B_ESTB1000_1 (ESTROGEN RECEPTOR)	5wq0	STAGE 0 SPORULATION PROTEIN (Paenisporosarcin a sp. TG-14)	5 / 10	MET B 71 LEU B 68 ALA B 66 MET B 59 LEU B 42	None	1.40A	5dxeB-5wq0B: undetectable	5dxeB-5wq0B: 23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HYR_A_ESTA601_1 (ESTROGEN RECEPTOR)	5wq0	STAGE 0 SPORULATION PROTEIN (Paenisporosarcin a sp. TG-14)	5 / 10	MET B 71 LEU B 68 ALA B 66 MET B 59 LEU B 42	None	1.40A	5hyrA-5wq0B: undetectable	5hyrA-5wq0B: 23.05

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1PCG_B_ESTB2_1","ESTROGEN RECEPTOR","5wq0","STAGE 0 SPORULATION PROTEIN","Paenisporosarcina sp. TG-14",5,"MET B  71;LEU B  68;ALA B  66;MET B  59;LEU B  42","None","1.38A","1pcgB-5wq0B:undetectable","1pcgB-5wq0B:23.43"],["1S9P_A_DESA459_1","ESTROGEN-RELATED RECEPTOR GAMMA","5wq0","STAGE 0 SPORULATION PROTEIN","Paenisporosarcina sp. TG-14",5,"LEU B  15;ALA B   9;LEU B  53;VAL B   6;LEU B 115","None","1.03A","1s9pA-5wq0B:undetectable","1s9pA-5wq0B:22.69"],["1S9P_B_DESB459_1","ESTROGEN-RELATED RECEPTOR GAMMA","5wq0","STAGE 0 SPORULATION PROTEIN","Paenisporosarcina sp. TG-14",5,"LEU B  15;ALA B   9;LEU B  53;VAL B   6;LEU B 115","None","1.05A","1s9pB-5wq0B:undetectable","1s9pB-5wq0B:22.69"],["1S9P_D_DESD600_1","ESTROGEN-RELATED RECEPTOR GAMMA","5wq0","STAGE 0 SPORULATION PROTEIN","Paenisporosarcina sp. TG-14",5,"LEU B  15;ALA B   9;LEU B  53;VAL B   6;LEU B 115","None","1.00A","1s9pD-5wq0B:undetectable","1s9pD-5wq0B:22.69"],["2OCF_A_ESTA596_1","ESTROGEN RECEPTOR","5wq0","STAGE 0 SPORULATION PROTEIN","Paenisporosarcina sp. TG-14",5,"MET B  71;LEU B  68;ALA B  66;MET B  59;LEU B  42","None","1.39A","2ocfA-5wq0B:undetectable","2ocfA-5wq0B:17.85"],["4XT8_A_TMQA302_1","RV2671","5wq0","STAGE 0 SPORULATION PROTEIN","Paenisporosarcina sp. TG-14",5,"ILE B   4;GLY B 124;ALA B 123;ASP B  51;GLU B   2","None","1.31A","4xt8A-5wq0B:undetectable","4xt8A-5wq0B:17.44"],["5DXB_A_ESTA1000_1","ESTROGEN RECEPTOR","5wq0","STAGE 0 SPORULATION PROTEIN","Paenisporosarcina sp. TG-14",5,"MET B  71;LEU B  68;ALA B  66;MET B  59;LEU B  42","None","1.40A","5dxbA-5wq0B:undetectable","5dxbA-5wq0B:23.11"],["5DXE_B_ESTB1000_1","ESTROGEN RECEPTOR","5wq0","STAGE 0 SPORULATION PROTEIN","Paenisporosarcina sp. TG-14",5,"MET B  71;LEU B  68;ALA B  66;MET B  59;LEU B  42","None","1.40A","5dxeB-5wq0B:undetectable","5dxeB-5wq0B:23.11"],["5HYR_A_ESTA601_1","ESTROGEN RECEPTOR","5wq0","STAGE 0 SPORULATION PROTEIN","Paenisporosarcina sp. TG-14",5,"MET B  71;LEU B  68;ALA B  66;MET B  59;LEU B  42","None","1.40A","5hyrA-5wq0B:undetectable","5hyrA-5wq0B:23.05"]]