SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wqg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PKV_A_RBFA100_1 (RIBOFLAVIN SYNTHASE ALPHA CHAIN)	5wqg	ISOMERASE TRT14 (Aspergillus terreus)	5 / 11	LEU A 90 ILE A 78 THR A 77 ILE A 108 VAL A 86	None	1.24A	1pkvA-5wqgA: undetectable 1pkvB-5wqgA: undetectable	1pkvA-5wqgA: 23.46 1pkvB-5wqgA: 23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PKV_B_RBFB101_1 (RIBOFLAVIN SYNTHASE ALPHA CHAIN)	5wqg	ISOMERASE TRT14 (Aspergillus terreus)	5 / 11	ILE A 108 VAL A 86 LEU A 90 ILE A 78 THR A 77	None	1.22A	1pkvA-5wqgA: undetectable 1pkvB-5wqgA: undetectable	1pkvA-5wqgA: 23.46 1pkvB-5wqgA: 23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LNX_A_T44A501_1 (THYROID HORMONE RECEPTOR ALPHA)	5wqg	ISOMERASE TRT14 (Aspergillus terreus)	4 / 6	SER A 53 GLU A 52 THR A 32 ARG A 31	None	1.35A	4lnxA-5wqgA: undetectable	4lnxA-5wqgA: 22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M50_B_TA1B502_1 (TUBULIN BETA-2B CHAIN)	5wqg	ISOMERASE TRT14 (Aspergillus terreus)	5 / 12	VAL A 79 ASP A 80 GLU A 81 THR A 32 PRO A 3	None	1.41A	5m50B-5wqgA: undetectable	5m50B-5wqgA: 16.36

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1PKV_A_RBFA100_1","RIBOFLAVIN SYNTHASE ALPHA CHAIN;RIBOFLAVIN SYNTHASE ALPHA CHAIN","5wqg","ISOMERASE TRT14","Aspergillus terreus",5,"LEU A  90;ILE A  78;THR A  77;ILE A 108;VAL A  86","None","1.24A","1pkvA-5wqgA:undetectable;1pkvB-5wqgA:undetectable","1pkvA-5wqgA:23.46;1pkvB-5wqgA:23.46"],["1PKV_B_RBFB101_1","RIBOFLAVIN SYNTHASE ALPHA CHAIN;RIBOFLAVIN SYNTHASE ALPHA CHAIN","5wqg","ISOMERASE TRT14","Aspergillus terreus",5,"ILE A 108;VAL A  86;LEU A  90;ILE A  78;THR A  77","None","1.22A","1pkvA-5wqgA:undetectable;1pkvB-5wqgA:undetectable","1pkvA-5wqgA:23.46;1pkvB-5wqgA:23.46"],["4LNX_A_T44A501_1","THYROID HORMONE RECEPTOR ALPHA","5wqg","ISOMERASE TRT14","Aspergillus terreus",4,"SER A  53;GLU A  52;THR A  32;ARG A  31","None","1.35A","4lnxA-5wqgA:undetectable","4lnxA-5wqgA:22.76"],["5M50_B_TA1B502_1","TUBULIN BETA-2B CHAIN","5wqg","ISOMERASE TRT14","Aspergillus terreus",5,"VAL A  79;ASP A  80;GLU A  81;THR A  32;PRO A   3","None","1.41A","5m50B-5wqgA:undetectable","5m50B-5wqgA:16.36"]]