SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wql'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_A_ADNA601_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		5 / 12 LEU C  85
GLU C 125
ASP C  79
LEU C 165
LEU C 162
 None
 1.24A 1d4fA-5wqlC:
undetectable		 1d4fA-5wqlC:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		5 / 12 LEU C  85
GLU C 125
ASP C  79
LEU C 165
LEU C 162
 None
 1.29A 1d4fB-5wqlC:
undetectable		 1d4fB-5wqlC:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		5 / 12 LEU C  85
GLU C 125
ASP C  79
LEU C 165
LEU C 162
 None
 1.28A 1d4fD-5wqlC:
undetectable		 1d4fD-5wqlC:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		4 / 8 SER C 503
ASN C 238
GLN C 236
PHE C 237
 None
 1.11A 1p6kB-5wqlC:
undetectable		 1p6kB-5wqlC:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_0
(HYPOTHETICAL PROTEIN
PH0226)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		5 / 12 GLY C 476
ILE C 456
SER C 452
ALA C 459
SER C 518
 None
 1.15A 1ve3A-5wqlC:
undetectable		 1ve3A-5wqlC:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		4 / 8 SER C 503
ASN C 238
GLN C 236
PHE C 237
 None
 1.15A 1zzuA-5wqlC:
undetectable		 1zzuA-5wqlC:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		4 / 8 SER C 503
ASN C 238
GLN C 236
PHE C 237
 None
 1.13A 1zzuB-5wqlC:
undetectable		 1zzuB-5wqlC:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_2
(ADENOSINE KINASE)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		4 / 4 ALA C 399
VAL C 404
PHE C 365
THR C 370
 None
 1.24A 2pkkA-5wqlC:
undetectable		 2pkkA-5wqlC:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		3 / 3 ASP C 545
ASN C 546
THR C 507
 None
 0.60A 2pymB-5wqlC:
undetectable		 2pymB-5wqlC:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA142_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		4 / 5 PRO C 412
ILE C 411
GLY C 408
LYS C 439
 None
 1.06A 2qeuA-5wqlC:
undetectable
2qeuC-5wqlC:
undetectable		 2qeuA-5wqlC:
12.46
2qeuC-5wqlC:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_A_IBPA1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		4 / 7 ILE C 319
LEU C 320
GLY C 323
GLY C 279
 None
 0.80A 2wd9A-5wqlC:
undetectable		 2wd9A-5wqlC:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN3_A_ID8A1356_1
(THYROXINE-BINDING
GLOBULIN)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		4 / 8 LEU C 442
LEU C 406
LEU C 377
ARG C 466
 None
 1.01A 2xn3A-5wqlC:
undetectable
2xn3B-5wqlC:
undetectable		 2xn3A-5wqlC:
21.00
2xn3B-5wqlC:
5.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		5 / 12 THR C 239
LEU C 245
VAL C 251
ASP C 342
ILE C 338
 None
 1.25A 3bf1A-5wqlC:
undetectable
3bf1B-5wqlC:
undetectable		 3bf1A-5wqlC:
16.52
3bf1B-5wqlC:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		5 / 12 LEU C 392
ASN C 395
VAL C 373
ILE C 362
THR C 370
 None
 0.91A 3c6gA-5wqlC:
undetectable		 3c6gA-5wqlC:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_B_D2VB602_1
(CYTOCHROME P450 2R1)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		5 / 12 LEU C 392
ASN C 395
VAL C 373
ILE C 362
THR C 370
 None
 0.94A 3czhB-5wqlC:
undetectable		 3czhB-5wqlC:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_A_DX4A270_0
(PTERIDINE REDUCTASE
1)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		4 / 6 ARG C 188
SER C 132
ASP C 167
PRO C 137
 None
 1.49A 3jqaA-5wqlC:
4.2		 3jqaA-5wqlC:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		4 / 8 SER C 503
ASN C 238
GLN C 236
PHE C 237
 None
 1.14A 3n62A-5wqlC:
undetectable		 3n62A-5wqlC:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		5 / 12 TYR C 438
ALA C 467
GLY C 465
SER C 561
ASP C 463
 None
 1.43A 3ou6D-5wqlC:
undetectable		 3ou6D-5wqlC:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OYA_A_RLTA398_1
(PFV INTEGRASE)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		4 / 8 GLN C  40
PRO C 499
PRO C 496
GLN C 492
 None
 1.08A 3oyaA-5wqlC:
undetectable		 3oyaA-5wqlC:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_1
(MNMC2)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		4 / 4 GLU C 670
ASP C 665
ASP C 563
GLU C 570
 None
 1.41A 3vywB-5wqlC:
undetectable		 3vywB-5wqlC:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_MTLA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		4 / 6 GLU C 208
ARG C 232
ASP C 209
ARG C 299
 None
 1.40A 4kcnA-5wqlC:
undetectable		 4kcnA-5wqlC:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_MTLA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		4 / 6 GLU C 208
ARG C 232
ASP C 301
ARG C 299
 None
 1.41A 4kcnA-5wqlC:
undetectable		 4kcnA-5wqlC:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB806_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		4 / 7 SER C 503
ASN C 238
GLN C 236
PHE C 237
 None
 1.18A 4kcnB-5wqlC:
undetectable		 4kcnB-5wqlC:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		4 / 7 ASP C 280
SER C 277
ALA C 275
SER C 273
 None
 1.19A 4lv9A-5wqlC:
2.3
4lv9B-5wqlC:
undetectable		 4lv9A-5wqlC:
23.64
4lv9B-5wqlC:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		3 / 3 ASP C 491
TYR C 490
TRP C 498
 None
 1.44A 4p7nA-5wqlC:
undetectable		 4p7nA-5wqlC:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_E_ACTE406_0
(PROTON-GATED ION
CHANNEL)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		4 / 5 ILE C 588
ARG C 448
TYR C 655
GLU C 472
 None
 1.10A 4zzcE-5wqlC:
undetectable		 4zzcE-5wqlC:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		4 / 8 LEU C 442
MET C 461
LEU C 392
ILE C 362
 None
 0.74A 5mzjA-5wqlC:
undetectable		 5mzjA-5wqlC:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND3_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		5 / 12 VAL C 469
LEU C 392
ALA C 458
ARG C 448
ARG C 513
 None
 1.28A 5nd3B-5wqlC:
2.0		 5nd3B-5wqlC:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		5 / 12 VAL C 469
LEU C 392
ALA C 458
ARG C 448
ARG C 513
 None
 1.12A 5nd4B-5wqlC:
undetectable		 5nd4B-5wqlC:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		5 / 12 VAL C 469
LEU C 392
ALA C 458
ARG C 448
ARG C 513
 None
 1.21A 5nd7B-5wqlC:
2.0		 5nd7B-5wqlC:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB602_0
(ACETYLCHOLINESTERASE)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		4 / 8 THR C 190
LEU C 191
TYR C 195
VAL C 133
 None
 1.19A 5ov9B-5wqlC:
undetectable		 5ov9B-5wqlC:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_MTLA805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		4 / 8 SER C 503
ASN C 238
GLN C 236
PHE C 237
 None
 1.13A 5vunA-5wqlC:
undetectable		 5vunA-5wqlC:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		4 / 8 SER C 503
ASN C 238
GLN C 236
PHE C 237
 None
 1.16A 5vuoB-5wqlC:
undetectable		 5vuoB-5wqlC:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_1
(ADENOSYLHOMOCYSTEINA
SE)		 5wql TAIL-SPECIFIC
PROTEASE
(Escherichia
coli) 		5 / 10 GLY C 107
GLU C 103
VAL C 111
ASP C 110
ILE C  70
 None
 1.23A 6exiB-5wqlC:
2.2		 6exiB-5wqlC:
8.66