SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wsf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M45_A_ACTA803_0 (ACETONE CARBOXYLASE ALPHA SUBUNIT)	5wsf	UNCHARACTERIZED PROTEIN TM1459 (Thermotoga maritima)	4 / 4	GLU A 59 PRO A 109 ILE A 108 LEU A 107	None	0.94A	5m45A-5wsfA: undetectable	5m45A-5wsfA: 10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M45_D_ACTD803_0 (ACETONE CARBOXYLASE ALPHA SUBUNIT)	5wsf	UNCHARACTERIZED PROTEIN TM1459 (Thermotoga maritima)	4 / 4	GLU A 59 PRO A 109 ILE A 108 LEU A 107	None	1.02A	5m45D-5wsfA: undetectable	5m45D-5wsfA: 10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M45_G_ACTG803_0 (ACETONE CARBOXYLASE ALPHA SUBUNIT)	5wsf	UNCHARACTERIZED PROTEIN TM1459 (Thermotoga maritima)	4 / 4	GLU A 59 PRO A 109 ILE A 108 LEU A 107	None	0.93A	5m45G-5wsfA: undetectable	5m45G-5wsfA: 10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M45_J_ACTJ803_0 (ACETONE CARBOXYLASE ALPHA SUBUNIT)	5wsf	UNCHARACTERIZED PROTEIN TM1459 (Thermotoga maritima)	4 / 4	GLU A 59 PRO A 109 ILE A 108 LEU A 107	None	1.01A	5m45J-5wsfA: undetectable	5m45J-5wsfA: 10.70

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["5M45_A_ACTA803_0","ACETONE CARBOXYLASE ALPHA SUBUNIT","5wsf","UNCHARACTERIZED PROTEIN TM1459","Thermotoga maritima",4,"GLU A  59;PRO A 109;ILE A 108;LEU A 107","None","0.94A","5m45A-5wsfA:undetectable","5m45A-5wsfA:10.70"],["5M45_D_ACTD803_0","ACETONE CARBOXYLASE ALPHA SUBUNIT","5wsf","UNCHARACTERIZED PROTEIN TM1459","Thermotoga maritima",4,"GLU A  59;PRO A 109;ILE A 108;LEU A 107","None","1.02A","5m45D-5wsfA:undetectable","5m45D-5wsfA:10.70"],["5M45_G_ACTG803_0","ACETONE CARBOXYLASE ALPHA SUBUNIT","5wsf","UNCHARACTERIZED PROTEIN TM1459","Thermotoga maritima",4,"GLU A  59;PRO A 109;ILE A 108;LEU A 107","None","0.93A","5m45G-5wsfA:undetectable","5m45G-5wsfA:10.70"],["5M45_J_ACTJ803_0","ACETONE CARBOXYLASE ALPHA SUBUNIT","5wsf","UNCHARACTERIZED PROTEIN TM1459","Thermotoga maritima",4,"GLU A  59;PRO A 109;ILE A 108;LEU A 107","None","1.01A","5m45J-5wsfA:undetectable","5m45J-5wsfA:10.70"]]