SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wso'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)
5wso NS3 HELICASE
(Pestivirus
A)
4 / 7 VAL A 313
SER A 343
ARG A 309
LEU A 308
None
1.15A 2f78A-5wsoA:
undetectable
2f78A-5wsoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_2
(PROTEASE)
5wso NS3 HELICASE
(Pestivirus
A)
5 / 9 ARG A 408
ALA A 415
VAL A 403
ILE A 387
PRO A 406
None
1.12A 3el4B-5wsoA:
undetectable
3el4B-5wsoA:
28.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)
5wso NS3 HELICASE
(Pestivirus
A)
4 / 7 HIS A 595
GLU A 651
PHE A 614
PRO A 642
None
1.39A 3ql6A-5wsoA:
undetectable
3ql6A-5wsoA:
9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)
5wso NS3 HELICASE
(Pestivirus
A)
4 / 8 SER A 549
ILE A 544
ILE A 540
ILE A 578
None
0.84A 4dtaB-5wsoA:
undetectable
4dtaB-5wsoA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
5wso NS3 HELICASE
(Pestivirus
A)
4 / 8 LEU A 236
VAL A 347
VAL A 252
TYR A 317
None
1.04A 4pwdC-5wsoA:
undetectable
4pwdC-5wsoA:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN)
5wso NS3 HELICASE
(Pestivirus
A)
5 / 12 ARG A 537
ALA A 602
ALA A 332
GLY A 539
TYR A 538
None
1.28A 4r29C-5wsoA:
undetectable
4r29C-5wsoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZF8_A_MYTA502_1
(BIFUNCTIONAL
P-450/NADPH-P450
REDUCTASE)
5wso NS3 HELICASE
(Pestivirus
A)
4 / 6 VAL A 405
LEU A 418
ILE A 387
ALA A 388
None
0.65A 4zf8A-5wsoA:
undetectable
4zf8A-5wsoA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_A_010A609_0
(HNL ISOENZYME 5)
5wso NS3 HELICASE
(Pestivirus
A)
5 / 11 ALA A 415
VAL A 449
LEU A 418
LEU A 385
VAL A 403
None
1.26A 5eb5A-5wsoA:
undetectable
5eb5A-5wsoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)
5wso NS3 HELICASE
(Pestivirus
A)
4 / 5 THR A 350
ALA A 351
THR A 352
HIS A 324
None
1.21A 5ecmA-5wsoA:
undetectable
5ecmA-5wsoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECE_C_DVAC3010_0
(VLM2
DODECADEPSIPEPTIDE)
5wso NS3 HELICASE
(Pestivirus
A)
3 / 3 ALA A 311
PHE A 340
GLN A 305
None
0.81A 6eceA-5wsoA:
undetectable
6eceA-5wsoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_A_FJQA501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)
5wso NS3 HELICASE
(Pestivirus
A)
5 / 10 ALA A 676
LEU A 677
VAL A 680
VAL A 479
ILE A 567
None
1.02A 6h1lA-5wsoA:
undetectable
6h1lA-5wsoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_A_FJQA501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)
5wso NS3 HELICASE
(Pestivirus
A)
5 / 10 ALA A 676
LEU A 677
VAL A 680
VAL A 479
THR A 547
None
0.90A 6h1lA-5wsoA:
undetectable
6h1lA-5wsoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_B_FJQB501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)
5wso NS3 HELICASE
(Pestivirus
A)
5 / 11 ALA A 676
LEU A 677
VAL A 680
VAL A 479
THR A 547
None
0.92A 6h1lB-5wsoA:
undetectable
6h1lB-5wsoA:
undetectable