SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wsy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5wsy UNCHARACTERIZED
PROTEIN
(Streptomyces
avermitilis) 		4 / 8 TYR A  53
CYH A  68
VAL A 118
ILE A  48
 7UC  A 201 (-4.7A)
None
None
None
 1.04A 4aftD-5wsyA:
undetectable
4aftE-5wsyA:
undetectable		 4aftD-5wsyA:
17.78
4aftE-5wsyA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QD3_A_5AEA201_1
(PEPTIDYL-TRNA
HYDROLASE)		 5wsy UNCHARACTERIZED
PROTEIN
(Streptomyces
avermitilis) 		5 / 9 GLY A  88
VAL A  81
SER A  80
VAL A  77
LEU A  76
 None
 1.11A 4qd3A-5wsyA:
undetectable		 4qd3A-5wsyA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5wsy UNCHARACTERIZED
PROTEIN
(Streptomyces
avermitilis) 		3 / 3 VAL A  16
TYR A  75
GLN A  71
 None
 0.74A 5qgrA-5wsyA:
undetectable		 5qgrA-5wsyA:
21.63