SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wte'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5wte VP3
(Hepatovirus
A) 		5 / 12 VAL C 224
LEU C 231
ALA C 228
LEU C 115
ALA C 100
 None
 1.14A 1sa1A-5wteC:
undetectable
1sa1B-5wteC:
undetectable		 1sa1A-5wteC:
18.78
1sa1B-5wteC:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5wte VP3
(Hepatovirus
A) 		5 / 12 VAL C 224
LEU C 231
ALA C 228
LEU C 115
ALA C 100
 None
 1.17A 1sa1C-5wteC:
undetectable
1sa1D-5wteC:
undetectable		 1sa1C-5wteC:
18.78
1sa1D-5wteC:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5wte VP3
(Hepatovirus
A) 		5 / 10 GLY C 164
GLN C 166
MET C 160
ASP C 161
ILE C 162
 None
 1.38A 3fhjB-5wteC:
undetectable		 3fhjB-5wteC:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5wte VP3
(Hepatovirus
A) 		5 / 10 GLY C 164
GLN C 166
MET C 160
ASP C 161
ILE C 162
 None
 1.39A 3fhjC-5wteC:
undetectable		 3fhjC-5wteC:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA424_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5wte VP3
(Hepatovirus
A) 		4 / 8 LEU C 115
ARG C 182
GLY C 138
PRO C 137
 None
 1.07A 3hcrA-5wteC:
undetectable		 3hcrA-5wteC:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 5wte VP3
(Hepatovirus
A) 		4 / 6 ASP C 178
ASP C  82
ARG C 185
ASN C 184
 None
 1.24A 5l6eA-5wteC:
undetectable		 5l6eA-5wteC:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0I_A_TRPA402_0
(TRYPTOPHAN--TRNA
LIGASE)		 5wte VP3
(Hepatovirus
A) 		5 / 9 GLY C 164
GLN C 166
MET C 160
ASP C 161
ILE C 162
 None
 1.40A 5v0iA-5wteC:
undetectable		 5v0iA-5wteC:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0I_B_TRPB402_0
(TRYPTOPHAN--TRNA
LIGASE)		 5wte VP3
(Hepatovirus
A) 		5 / 9 GLY C 164
GLN C 166
MET C 160
ASP C 161
ILE C 162
 None
 1.42A 5v0iB-5wteC:
undetectable		 5v0iB-5wteC:
21.76