SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wtl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA501_1
(CYTOCHROME P450 2C8)		 5wtl OMPA FAMILY PROTEIN
(Capnocytophaga
gingivalis) 		5 / 11 GLY A 416
ILE A 371
ALA A 348
VAL A 409
ILE A 360
 None
 1.08A 2nnhA-5wtlA:
undetectable		 2nnhA-5wtlA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 5wtl OMPA FAMILY PROTEIN
(Capnocytophaga
gingivalis) 		3 / 3 ASP A 281
ASP A 283
ASN A 301
 CA  A1008 ( 2.8A)
CA  A1007 ( 2.7A)
None
 0.77A 4q5mA-5wtlA:
undetectable		 4q5mA-5wtlA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 5wtl OMPA FAMILY PROTEIN
(Capnocytophaga
gingivalis) 		3 / 3 ASP A 310
ASP A 312
ASN A 330
 CA  A1009 ( 2.8A)
CA  A1009 ( 2.7A)
None
 0.69A 4q5mA-5wtlA:
undetectable		 4q5mA-5wtlA:
15.27