SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wtn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 5wtn REPLICATION
INITIATION AND
MEMBRANE ATTACHMENT
PROTEIN
(Geobacillus
stearothermophil
us) 		4 / 6 PHE A 211
LEU A 266
VAL A 229
VAL A 220
 None
 1.12A 1dz4A-5wtnA:
undetectable		 1dz4A-5wtnA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 5wtn REPLICATION
INITIATION AND
MEMBRANE ATTACHMENT
PROTEIN
(Geobacillus
stearothermophil
us) 		4 / 6 PHE A 211
LEU A 266
VAL A 229
VAL A 220
 None
 1.12A 1dz4B-5wtnA:
undetectable		 1dz4B-5wtnA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 5wtn REPLICATION
INITIATION AND
MEMBRANE ATTACHMENT
PROTEIN
(Geobacillus
stearothermophil
us) 		4 / 8 PHE A 211
LEU A 266
VAL A 229
VAL A 220
 None
 1.13A 1dz9A-5wtnA:
undetectable		 1dz9A-5wtnA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 5wtn REPLICATION
INITIATION AND
MEMBRANE ATTACHMENT
PROTEIN
(Geobacillus
stearothermophil
us) 		4 / 5 PHE A 211
LEU A 266
VAL A 229
VAL A 220
 None
 1.12A 1t88B-5wtnA:
undetectable		 1t88B-5wtnA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 5wtn REPLICATION
INITIATION AND
MEMBRANE ATTACHMENT
PROTEIN
(Geobacillus
stearothermophil
us) 		4 / 8 PHE A 211
LEU A 266
VAL A 229
VAL A 220
 None
 1.09A 1uyuA-5wtnA:
undetectable		 1uyuA-5wtnA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 5wtn REPLICATION
INITIATION AND
MEMBRANE ATTACHMENT
PROTEIN
(Geobacillus
stearothermophil
us) 		4 / 8 PHE A 211
LEU A 266
VAL A 229
VAL A 220
 None
 1.15A 1uyuB-5wtnA:
undetectable		 1uyuB-5wtnA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 5wtn REPLICATION
INITIATION AND
MEMBRANE ATTACHMENT
PROTEIN
(Geobacillus
stearothermophil
us) 		4 / 6 PHE A 211
LEU A 266
VAL A 229
VAL A 220
 None
 1.07A 2feuA-5wtnA:
undetectable		 2feuA-5wtnA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5wtn REPLICATION
INITIATION AND
MEMBRANE ATTACHMENT
PROTEIN
(Geobacillus
stearothermophil
us) 		4 / 5 PHE A 211
LEU A 266
VAL A 229
VAL A 220
 None
 1.11A 2m56A-5wtnA:
undetectable		 2m56A-5wtnA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5wtn REPLICATION
INITIATION AND
MEMBRANE ATTACHMENT
PROTEIN
(Geobacillus
stearothermophil
us) 		4 / 6 PHE A 211
LEU A 266
VAL A 229
VAL A 220
 None
 1.18A 2zawA-5wtnA:
undetectable		 2zawA-5wtnA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_F_TOPF200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 5wtn REPLICATION
INITIATION AND
MEMBRANE ATTACHMENT
PROTEIN
(Geobacillus
stearothermophil
us) 		5 / 10 ALA A 232
LEU A 266
VAL A 225
LEU A 215
PHE A 211
 None
 1.17A 3fl9F-5wtnA:
undetectable		 3fl9F-5wtnA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5wtn REPLICATION
INITIATION AND
MEMBRANE ATTACHMENT
PROTEIN
(Geobacillus
stearothermophil
us) 		4 / 6 PHE A 211
LEU A 266
VAL A 229
VAL A 220
 None
 1.07A 3fwgA-5wtnA:
undetectable		 3fwgA-5wtnA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5wtn REPLICATION
INITIATION AND
MEMBRANE ATTACHMENT
PROTEIN
(Geobacillus
stearothermophil
us) 		4 / 5 VAL A 254
ILE A 233
PHE A 208
PHE A 212
 None
 1.05A 3owxB-5wtnA:
undetectable		 3owxB-5wtnA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 5wtn REPLICATION
INITIATION AND
MEMBRANE ATTACHMENT
PROTEIN
(Geobacillus
stearothermophil
us) 		4 / 6 PHE A 211
LEU A 266
VAL A 229
VAL A 220
 None
 1.07A 3wrhE-5wtnA:
undetectable		 3wrhE-5wtnA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 5wtn REPLICATION
INITIATION AND
MEMBRANE ATTACHMENT
PROTEIN
(Geobacillus
stearothermophil
us) 		4 / 6 PHE A 211
LEU A 266
VAL A 229
VAL A 220
 None
 1.09A 3wrjE-5wtnA:
undetectable		 3wrjE-5wtnA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5wtn REPLICATION
INITIATION AND
MEMBRANE ATTACHMENT
PROTEIN
(Geobacillus
stearothermophil
us) 		4 / 6 PHE A 211
LEU A 266
VAL A 229
VAL A 220
 None
 1.10A 4ek1A-5wtnA:
undetectable		 4ek1A-5wtnA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5wtn REPLICATION
INITIATION AND
MEMBRANE ATTACHMENT
PROTEIN
(Geobacillus
stearothermophil
us) 		4 / 6 PHE A 211
LEU A 266
VAL A 229
VAL A 220
 None
 1.14A 4g3rA-5wtnA:
undetectable		 4g3rA-5wtnA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 5wtn REPLICATION
INITIATION AND
MEMBRANE ATTACHMENT
PROTEIN
(Geobacillus
stearothermophil
us) 		4 / 6 PHE A 211
LEU A 266
VAL A 229
VAL A 220
 None
 1.14A 4kkyX-5wtnA:
undetectable		 4kkyX-5wtnA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5wtn REPLICATION
INITIATION AND
MEMBRANE ATTACHMENT
PROTEIN
(Geobacillus
stearothermophil
us) 		4 / 5 PHE A 211
LEU A 266
VAL A 229
VAL A 220
 None
 1.14A 4l49A-5wtnA:
undetectable		 4l49A-5wtnA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5wtn REPLICATION
INITIATION AND
MEMBRANE ATTACHMENT
PROTEIN
(Geobacillus
stearothermophil
us) 		4 / 8 PHE A 211
LEU A 266
VAL A 229
VAL A 220
 None
 1.13A 4l4dA-5wtnA:
undetectable		 4l4dA-5wtnA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5wtn REPLICATION
INITIATION AND
MEMBRANE ATTACHMENT
PROTEIN
(Geobacillus
stearothermophil
us) 		4 / 8 PHE A 211
LEU A 266
VAL A 229
VAL A 220
 None
 1.11A 4l4eA-5wtnA:
undetectable		 4l4eA-5wtnA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5wtn REPLICATION
INITIATION AND
MEMBRANE ATTACHMENT
PROTEIN
(Geobacillus
stearothermophil
us) 		4 / 8 PHE A 211
LEU A 266
VAL A 229
VAL A 220
 None
 1.10A 4l4fA-5wtnA:
undetectable		 4l4fA-5wtnA:
22.46