SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wtp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AKE_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5wtp OMPA FAMILY PROTEIN
(Capnocytophaga
gingivalis) 		5 / 12 GLY A 387
GLY A 429
GLN A 403
ILE A 385
GLN A 426
 None
 1.19A 2akeA-5wtpA:
undetectable		 2akeA-5wtpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA601_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5wtp OMPA FAMILY PROTEIN
(Capnocytophaga
gingivalis) 		5 / 12 GLY A 387
GLY A 429
GLN A 403
ILE A 385
GLN A 426
 None
 1.18A 2azxA-5wtpA:
undetectable		 2azxA-5wtpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_B_TRPB603_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5wtp OMPA FAMILY PROTEIN
(Capnocytophaga
gingivalis) 		5 / 12 GLY A 387
GLY A 429
GLN A 403
ILE A 385
GLN A 426
 None
 1.22A 2azxB-5wtpA:
undetectable		 2azxB-5wtpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DR2_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5wtp OMPA FAMILY PROTEIN
(Capnocytophaga
gingivalis) 		5 / 11 GLY A 387
GLY A 429
GLN A 403
ILE A 385
GLN A 426
 None
 1.18A 2dr2A-5wtpA:
undetectable		 2dr2A-5wtpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)		 5wtp OMPA FAMILY PROTEIN
(Capnocytophaga
gingivalis) 		3 / 3 ARG A 422
ARG A 382
ILE A 418
 SO4  A 509 (-3.7A)
None
SO4  A 509 (-3.8A)
 0.91A 4b7qA-5wtpA:
undetectable		 4b7qA-5wtpA:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QCK_A_ASDA404_1
(3-KETOSTEROID-9-ALPH
A-MONOOXYGENASE
OXYGENASE SUBUNIT)		 5wtp OMPA FAMILY PROTEIN
(Capnocytophaga
gingivalis) 		5 / 12 ASN A 369
VAL A 367
LEU A 423
ASN A 373
GLY A 417
 None
 1.11A 4qckA-5wtpA:
undetectable		 4qckA-5wtpA:
11.62