SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wtq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2002_1
(SERUM ALBUMIN)
5wtq PROTEASOME ASSEMBLY
CHAPERONE 4

(Homo
sapiens)
4 / 9 PHE A 104
ALA A 105
VAL A 108
GLU A 109
None
0.49A 2vufA-5wtqA:
undetectable
2vufA-5wtqA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F5Z_A_BEZA302_0
(HALOALKANE
DEHALOGENASE)
5wtq PROTEASOME ASSEMBLY
CHAPERONE 4

(Homo
sapiens)
4 / 8 ASN A  99
PHE A 104
VAL A 108
TYR A  95
None
0.98A 4f5zA-5wtqA:
undetectable
4f5zA-5wtqA:
17.33