SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wua'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 5wua ATP-SENSITIVE INWARD
RECTIFIER POTASSIUM
CHANNEL
11,SUPERFOLDER GFP
(Mus
musculus;
synthetic
construct) 		3 / 3 ALA A  94
VAL A  89
TRP A  90
 None
 0.87A 1bdwA-5wuaA:
undetectable
1bdwB-5wuaA:
undetectable		 1bdwA-5wuaA:
4.23
1bdwB-5wuaA:
4.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTX_A_CVIA200_0
(HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR IN QACA
5'REGION)		 5wua ATP-SENSITIVE INWARD
RECTIFIER POTASSIUM
CHANNEL
11,SUPERFOLDER GFP
(Mus
musculus;
synthetic
construct) 		5 / 12 ILE A 215
ILE A 249
TYR A 304
ILE A 309
ALA A 187
 None
 0.89A 1jtxA-5wuaA:
undetectable		 1jtxA-5wuaA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_1
(MINERALOCORTICOID
RECEPTOR)		 5wua ATP-SENSITIVE INWARD
RECTIFIER POTASSIUM
CHANNEL
11,SUPERFOLDER GFP
(Mus
musculus;
synthetic
construct) 		5 / 12 LEU A  80
ALA A  87
SER A 118
LEU A 122
ARG A 136
 None
 1.46A 1ya3B-5wuaA:
undetectable		 1ya3B-5wuaA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUF_A_AEGA394_0
(BETA-SECRETASE 1)		 5wua ATP-SENSITIVE INWARD
RECTIFIER POTASSIUM
CHANNEL
11,SUPERFOLDER GFP
(Mus
musculus;
synthetic
construct) 		4 / 5 LEU A 251
ILE A 215
ILE A 210
GLY A 203
 None
 0.77A 3bufA-5wuaA:
undetectable		 3bufA-5wuaA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_C_DXCC92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5wua ATP-SENSITIVE INWARD
RECTIFIER POTASSIUM
CHANNEL
11,SUPERFOLDER GFP
(Mus
musculus;
synthetic
construct) 		4 / 4 VAL A 138
PHE A 123
PHE A  86
VAL A 151
 None
 1.14A 3rv5C-5wuaA:
undetectable
3rv5D-5wuaA:
undetectable		 3rv5C-5wuaA:
8.04
3rv5D-5wuaA:
8.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALC_L_TIQL1210_2
(ANTI-TICAGRELOR FAB
72, LIGHT CHAIN)		 5wua ATP-SENSITIVE INWARD
RECTIFIER POTASSIUM
CHANNEL
11,SUPERFOLDER GFP
(Mus
musculus;
synthetic
construct) 		4 / 8 GLY A 132
ILE A 114
SER A 113
GLY A 135
 None
 0.83A 5alcL-5wuaA:
3.6		 5alcL-5wuaA:
15.20