SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wue'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_1
(PROTEASE)		 5wue UNCHARACTERIZED
PROTEIN
(Sulfolobus
acidocaldarius) 		4 / 7 GLY A  50
ILE A  51
ALA A  21
ILE A  17
 None
 0.77A 1n49A-5wueA:
undetectable		 1n49A-5wueA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 5wue UNCHARACTERIZED
PROTEIN
(Sulfolobus
acidocaldarius) 		4 / 4 VAL A 160
ALA A 156
LEU A 201
PHE A 154
 None
SO4  A 301 (-3.0A)
SO4  A 301 ( 4.9A)
None
 1.12A 1q97B-5wueA:
undetectable		 1q97B-5wueA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)		 5wue UNCHARACTERIZED
PROTEIN
(Sulfolobus
acidocaldarius) 		5 / 12 PHE A  12
ILE A 186
GLY A 104
ALA A 100
SER A 109
 None
 1.12A 1sg9C-5wueA:
2.7		 1sg9C-5wueA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)		 5wue UNCHARACTERIZED
PROTEIN
(Sulfolobus
acidocaldarius) 		6 / 12 SER A 163
ALA A 111
GLY A 110
GLY A 128
ALA A 159
GLY A  49
 None
 1.49A 2pkmA-5wueA:
undetectable		 2pkmA-5wueA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_A_PFNA1372_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5wue UNCHARACTERIZED
PROTEIN
(Sulfolobus
acidocaldarius) 		5 / 11 LEU A  56
LEU A  57
LYS A  59
THR A  63
PRO A  62
 None
 1.46A 2x7hA-5wueA:
undetectable
2x7hB-5wueA:
undetectable		 2x7hA-5wueA:
20.69
2x7hB-5wueA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 5wue UNCHARACTERIZED
PROTEIN
(Sulfolobus
acidocaldarius) 		6 / 12 GLY A  42
SER A  44
GLY A 135
GLY A 136
LEU A  39
ALA A  25
 None
 1.36A 3douA-5wueA:
undetectable		 3douA-5wueA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 5wue UNCHARACTERIZED
PROTEIN
(Sulfolobus
acidocaldarius) 		5 / 10 SER A  23
LEU A 142
SER A 143
ILE A 138
GLY A 136
 None
 1.05A 3ijxB-5wueA:
undetectable
3ijxD-5wueA:
undetectable		 3ijxB-5wueA:
21.62
3ijxD-5wueA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB262_1
(GLUTAMATE RECEPTOR 2)		 5wue UNCHARACTERIZED
PROTEIN
(Sulfolobus
acidocaldarius) 		5 / 10 ILE A 138
GLY A 136
SER A  23
LEU A 142
SER A 143
 None
 0.99A 3ik6B-5wueA:
undetectable
3ik6E-5wueA:
undetectable		 3ik6B-5wueA:
21.62
3ik6E-5wueA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 5wue UNCHARACTERIZED
PROTEIN
(Sulfolobus
acidocaldarius) 		5 / 10 SER A  23
LEU A 142
SER A 143
ILE A 138
GLY A 136
 None
 0.98A 3iluB-5wueA:
undetectable
3iluE-5wueA:
undetectable		 3iluB-5wueA:
21.62
3iluE-5wueA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)		 5wue UNCHARACTERIZED
PROTEIN
(Sulfolobus
acidocaldarius) 		5 / 11 ILE A 138
GLY A 136
SER A  23
LEU A 142
SER A 143
 None
 1.00A 3iluB-5wueA:
undetectable
3iluE-5wueA:
undetectable		 3iluB-5wueA:
21.62
3iluE-5wueA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5wue UNCHARACTERIZED
PROTEIN
(Sulfolobus
acidocaldarius) 		5 / 12 GLY A  50
LEU A  57
THR A 131
GLY A 110
GLY A  16
 None
 1.13A 5d4uA-5wueA:
undetectable		 5d4uA-5wueA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5wue UNCHARACTERIZED
PROTEIN
(Sulfolobus
acidocaldarius) 		5 / 12 GLY A  50
LEU A  57
THR A 131
GLY A 110
GLY A  16
 None
 1.10A 5d4uB-5wueA:
undetectable		 5d4uB-5wueA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_A_PAUA602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 5wue UNCHARACTERIZED
PROTEIN
(Sulfolobus
acidocaldarius) 		4 / 7 GLY A 110
SER A  53
GLY A  50
ALA A 107
 None
 0.87A 5e26A-5wueA:
undetectable
5e26B-5wueA:
undetectable		 5e26A-5wueA:
21.98
5e26B-5wueA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_D_PAUD601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 5wue UNCHARACTERIZED
PROTEIN
(Sulfolobus
acidocaldarius) 		4 / 8 ALA A 107
GLY A 110
SER A  53
GLY A  50
 None
 0.86A 5e26C-5wueA:
undetectable
5e26D-5wueA:
undetectable		 5e26C-5wueA:
21.98
5e26D-5wueA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 5wue UNCHARACTERIZED
PROTEIN
(Sulfolobus
acidocaldarius) 		5 / 12 THR A 187
THR A 158
GLY A 102
ALA A 100
SER A 183
 None
 1.27A 5lf3b-5wueA:
undetectable		 5lf3b-5wueA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 5wue UNCHARACTERIZED
PROTEIN
(Sulfolobus
acidocaldarius) 		5 / 12 THR A 187
THR A 158
GLY A 102
ALA A 100
SER A 183
 None
 1.26A 5lf3N-5wueA:
undetectable		 5lf3N-5wueA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA205_0
(N-ACETYLTRANSFERASE)		 5wue UNCHARACTERIZED
PROTEIN
(Sulfolobus
acidocaldarius) 		4 / 4 ALA A  21
ALA A  46
ALA A  74
ALA A  77
 None
 0.77A 6gtqA-5wueA:
undetectable
6gtqB-5wueA:
0.0		 6gtqA-5wueA:
21.61
6gtqB-5wueA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA205_0
(N-ACETYLTRANSFERASE)		 5wue UNCHARACTERIZED
PROTEIN
(Sulfolobus
acidocaldarius) 		4 / 4 ALA A  74
ALA A  77
ALA A  21
ALA A  46
 None
 0.79A 6gtqA-5wueA:
undetectable
6gtqB-5wueA:
0.0		 6gtqA-5wueA:
21.61
6gtqB-5wueA:
21.61