SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wug'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB8_0
(GRAMICIDIN A)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
3 / 3 VAL A 315
VAL A 382
TRP A 313
None
0.97A 1bdwA-5wugA:
undetectable
1bdwB-5wugA:
undetectable
1bdwA-5wugA:
undetectable
1bdwB-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_B_SALB4005_1
(XANTHINE
DEHYDROGENASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 7 GLU A 536
THR A 923
VAL A 922
ALA A 785
None
1.08A 1fo4B-5wugA:
undetectable
1fo4B-5wugA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_D_NIOD223_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 5 GLY A 552
SER A 549
THR A 568
PHE A 551
None
1.30A 1icuC-5wugA:
undetectable
1icuD-5wugA:
undetectable
1icuC-5wugA:
17.51
1icuD-5wugA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_B_NIOB702_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 5 GLY A 552
SER A 549
THR A 568
PHE A 551
None
1.38A 1icvA-5wugA:
undetectable
1icvB-5wugA:
undetectable
1icvA-5wugA:
17.51
1icvB-5wugA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5R_A_RBFA859_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 11 LEU A 604
TYR A  39
ALA A 239
GLY A 237
PHE A  36
None
1.35A 1l5rA-5wugA:
undetectable
1l5rA-5wugA:
7.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7G_A_BCZA801_0
(NEURAMINIDASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 LEU A 620
ASP A 570
ARG A 576
GLU A 638
ARG A 635
None
1.36A 1l7gA-5wugA:
undetectable
1l7gA-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 8 THR A 500
PHE A 520
MET A 813
LEU A 529
None
0.99A 1lhvA-5wugA:
2.8
1lhvA-5wugA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1872_0
(FPRA)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 5 SER A 725
ASN A 753
ALA A 761
ASP A 754
None
1.21A 1lqtA-5wugA:
undetectable
1lqtB-5wugA:
undetectable
1lqtA-5wugA:
undetectable
1lqtB-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1429_0
(FPRA)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 5 SER A 725
ASN A 753
ALA A 761
ASP A 754
None
1.21A 1lquA-5wugA:
undetectable
1lquB-5wugA:
undetectable
1lquA-5wugA:
undetectable
1lquB-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 ILE A 694
GLY A 286
ALA A 259
SER A 267
TYR A 695
None
1.35A 1nbhA-5wugA:
2.5
1nbhA-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 ILE A 694
GLY A 286
ALA A 259
SER A 267
TYR A 695
None
1.35A 1nbhC-5wugA:
undetectable
1nbhC-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 ILE A 694
GLY A 286
ALA A 259
SER A 267
TYR A 695
None
1.35A 1nbhD-5wugA:
undetectable
1nbhD-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 8 ALA A 166
ASP A 210
ILE A 209
ILE A 162
None
0.91A 1p7lD-5wugA:
undetectable
1p7lD-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 8 ALA A 166
ASP A 210
ILE A 209
ILE A 162
None
0.92A 1p7lC-5wugA:
undetectable
1p7lC-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q13_A_TESA501_1
(PROSTAGLANDIN-E2
9-REDUCTASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 6 TYR A 605
GLU A 611
PRO A  32
VAL A  87
None
1.11A 1q13A-5wugA:
undetectable
1q13A-5wugA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 8 ALA A 166
ASP A 210
ILE A 209
ILE A 162
None
0.88A 1rg9B-5wugA:
undetectable
1rg9B-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 8 ALA A 166
ASP A 210
ILE A 209
ILE A 162
None
0.90A 1rg9A-5wugA:
undetectable
1rg9A-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 8 ALA A 166
ASP A 210
ILE A 209
ILE A 162
None
0.90A 1rg9D-5wugA:
undetectable
1rg9D-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 8 ALA A 166
ASP A 210
ILE A 209
ILE A 162
None
0.90A 1rg9C-5wugA:
undetectable
1rg9C-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 6 LEU A 243
TYR A  76
ARG A  78
LEU A 591
None
0.93A 1v54A-5wugA:
undetectable
1v54J-5wugA:
undetectable
1v54A-5wugA:
undetectable
1v54J-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 7 LEU A 243
TYR A  76
ARG A  78
LEU A 591
None
0.89A 1v54N-5wugA:
undetectable
1v54W-5wugA:
undetectable
1v54N-5wugA:
undetectable
1v54W-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_0
(HYPOTHETICAL PROTEIN
PH0226)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 ALA A 151
ILE A 147
ILE A  65
SER A  67
PHE A  69
None
1.07A 1ve3A-5wugA:
2.9
1ve3A-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 ALA A 151
ILE A 147
ILE A  65
SER A  67
PHE A  69
None
1.13A 1ve3B-5wugA:
undetectable
1ve3B-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_1
(AMINOMETHYLTRANSFERA
SE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
3 / 3 ASP A 282
GLU A 410
TYR A 352
None
0.86A 1wsvA-5wugA:
undetectable
1wsvA-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 6 LEU A 243
TYR A  76
ARG A  78
LEU A 591
None
0.95A 2dyrA-5wugA:
undetectable
2dyrJ-5wugA:
undetectable
2dyrA-5wugA:
undetectable
2dyrJ-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 7 LEU A 243
TYR A  76
ARG A  78
LEU A 591
None
0.89A 2dyrN-5wugA:
undetectable
2dyrW-5wugA:
undetectable
2dyrN-5wugA:
undetectable
2dyrW-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 6 LEU A 243
TYR A  76
ARG A  78
LEU A 591
None
0.97A 2dysA-5wugA:
undetectable
2dysJ-5wugA:
undetectable
2dysA-5wugA:
undetectable
2dysJ-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 6 LEU A 243
TYR A  76
ARG A  78
LEU A 591
None
0.89A 2dysN-5wugA:
undetectable
2dysW-5wugA:
undetectable
2dysN-5wugA:
undetectable
2dysW-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_D_SALD5006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 5 ARG A 534
THR A 766
LEU A 803
ALA A 530
None
1.44A 2e1qD-5wugA:
undetectable
2e1qD-5wugA:
5.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 6 LEU A 243
TYR A  76
ARG A  78
LEU A 591
None
0.89A 2eijA-5wugA:
undetectable
2eijJ-5wugA:
undetectable
2eijA-5wugA:
undetectable
2eijJ-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 8 LEU A 243
TYR A  76
ARG A  78
LEU A 591
None
0.83A 2eijN-5wugA:
undetectable
2eijW-5wugA:
undetectable
2eijN-5wugA:
undetectable
2eijW-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 7 LEU A 243
TYR A  76
ARG A  78
LEU A 591
None
0.89A 2eikA-5wugA:
undetectable
2eikJ-5wugA:
undetectable
2eikA-5wugA:
undetectable
2eikJ-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 8 LEU A 243
TYR A  76
ARG A  78
LEU A 591
None
0.85A 2eikN-5wugA:
undetectable
2eikW-5wugA:
undetectable
2eikN-5wugA:
undetectable
2eikW-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 6 LEU A 243
TYR A  76
ARG A  78
LEU A 591
None
0.90A 2eilA-5wugA:
undetectable
2eilJ-5wugA:
undetectable
2eilA-5wugA:
undetectable
2eilJ-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 8 LEU A 243
TYR A  76
ARG A  78
LEU A 591
None
0.87A 2eilN-5wugA:
undetectable
2eilW-5wugA:
undetectable
2eilN-5wugA:
undetectable
2eilW-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 5 LEU A 819
LEU A 776
ILE A 743
ALA A 812
None
0.78A 2i2zA-5wugA:
undetectable
2i2zA-5wugA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_B_ERYB1399_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 ASN A  88
VAL A  89
ASN A 615
LEU A 612
ALA A  37
None
1.14A 2iyfB-5wugA:
2.5
2iyfB-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNP_A_ROCA401_1
(PROTEASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 11 ALA A  43
ILE A 235
GLY A 232
ILE A 588
THR A 584
None
0.90A 2nnpA-5wugA:
undetectable
2nnpA-5wugA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOA_B_3TCB302_1
(DEOXYCYTIDINE KINASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 11 ILE A 815
LEU A 507
ALA A 824
ASP A 618
PHE A 551
None
1.50A 2noaB-5wugA:
2.8
2noaB-5wugA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_C_2FAC500_2
(ADENOSYLHOMOCYSTEINA
SE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 5 LEU A 646
GLN A 349
THR A 590
HIS A 628
None
1.36A 2zj0C-5wugA:
2.2
2zj0C-5wugA:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 6 LEU A 243
TYR A  76
ARG A  78
LEU A 591
None
1.03A 2zxwA-5wugA:
undetectable
2zxwJ-5wugA:
undetectable
2zxwA-5wugA:
undetectable
2zxwJ-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 LEU A 306
PHE A 228
GLY A  48
PRO A 250
VAL A 205
None
1.14A 2zzmA-5wugA:
undetectable
2zzmA-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 7 LEU A 243
TYR A  76
ARG A  78
LEU A 591
None
1.01A 3ablA-5wugA:
undetectable
3ablJ-5wugA:
undetectable
3ablA-5wugA:
undetectable
3ablJ-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 8 LEU A 243
TYR A  76
ARG A  78
LEU A 591
None
0.92A 3ablN-5wugA:
undetectable
3ablW-5wugA:
undetectable
3ablN-5wugA:
undetectable
3ablW-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 6 LEU A 243
TYR A  76
ARG A  78
LEU A 591
None
1.07A 3abmA-5wugA:
undetectable
3abmJ-5wugA:
undetectable
3abmA-5wugA:
undetectable
3abmJ-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 8 LEU A 243
TYR A  76
ARG A  78
LEU A 591
None
0.92A 3ag3N-5wugA:
undetectable
3ag3W-5wugA:
undetectable
3ag3N-5wugA:
undetectable
3ag3W-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 6 LEU A 243
TYR A  76
ARG A  78
LEU A 591
None
0.94A 3asnA-5wugA:
undetectable
3asnJ-5wugA:
undetectable
3asnA-5wugA:
undetectable
3asnJ-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 8 LEU A 243
TYR A  76
ARG A  78
LEU A 591
None
0.83A 3asnN-5wugA:
undetectable
3asnW-5wugA:
undetectable
3asnN-5wugA:
undetectable
3asnW-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 6 LEU A 243
TYR A  76
ARG A  78
LEU A 591
None
0.96A 3asoA-5wugA:
undetectable
3asoJ-5wugA:
undetectable
3asoA-5wugA:
undetectable
3asoJ-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_B_ADNB402_1
(UNCHARACTERIZED
PROTEIN MJ0883)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 10 GLY A 237
ILE A 161
ASN A 204
VAL A  68
LEU A 244
None
1.11A 3ay0B-5wugA:
undetectable
3ay0B-5wugA:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_A_SALA257_1
(TRANSCRIPTIONAL
REGULATOR)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 8 SER A 663
ALA A 569
THR A 544
THR A 547
None
0.84A 3bpxA-5wugA:
undetectable
3bpxB-5wugA:
undetectable
3bpxA-5wugA:
16.44
3bpxB-5wugA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 ILE A 563
GLY A 553
ASN A 814
LEU A 517
THR A 531
None
1.09A 3eeyE-5wugA:
undetectable
3eeyE-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 ILE A 563
GLY A 553
ASN A 814
LEU A 517
THR A 531
None
1.01A 3eeyF-5wugA:
undetectable
3eeyF-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_1
(PROTEASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 ALA A  43
ILE A 235
GLY A 232
ILE A 588
THR A 584
None
0.90A 3el4A-5wugA:
undetectable
3el4A-5wugA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 6 ILE A 658
THR A 568
PHE A 551
PHE A 818
None
1.16A 3elzB-5wugA:
undetectable
3elzB-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_1
(REPRESSOR PROTEIN
MPHR(A))
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 5 ASN A 633
ARG A 629
ASN A 277
ALA A 678
None
1.50A 3frqA-5wugA:
undetectable
3frqA-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_B_BCZB1001_0
(NEURAMINIDASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 LEU A 620
ASP A 570
ARG A 576
GLU A 638
ARG A 635
None
1.44A 3k39B-5wugA:
undetectable
3k39B-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_C_BCZC1001_0
(NEURAMINIDASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 LEU A 620
ASP A 570
ARG A 576
GLU A 638
ARG A 635
None
1.44A 3k39C-5wugA:
undetectable
3k39C-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_D_BCZD1001_0
(NEURAMINIDASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 LEU A 620
ASP A 570
ARG A 576
GLU A 638
ARG A 635
None
1.46A 3k39D-5wugA:
undetectable
3k39D-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_J_BCZJ1001_0
(NEURAMINIDASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 LEU A 620
ASP A 570
ARG A 576
GLU A 638
ARG A 635
None
1.41A 3k39J-5wugA:
undetectable
3k39J-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_K_BCZK1001_0
(NEURAMINIDASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 LEU A 620
ASP A 570
ARG A 576
GLU A 638
ARG A 635
None
1.43A 3k39K-5wugA:
undetectable
3k39K-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA302_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 6 LEU A 359
GLU A 410
PRO A 355
HIS A 403
None
1.17A 3ltwA-5wugA:
undetectable
3ltwA-5wugA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 9 VAL A 884
PHE A 940
ILE A 952
VAL A 874
VAL A 865
None
1.24A 3me6C-5wugA:
undetectable
3me6C-5wugA:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_SALB900_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 5 LEU A 902
TYR A 942
ILE A 949
ALA A 867
None
0.92A 3n8yB-5wugA:
undetectable
3n8yB-5wugA:
8.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEG_A_DAHA416_1
(PHENYLALANYL-TRNA
SYNTHETASE,
MITOCHONDRIAL)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 GLN A 231
GLN A 585
GLY A  82
GLY A 167
GLY A  84
None
1.17A 3tegA-5wugA:
undetectable
3tegA-5wugA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 LEU A 524
GLY A 553
GLY A 555
ILE A 532
LEU A 507
None
1.02A 3uj7B-5wugA:
undetectable
3uj7B-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_2
(NEURAMINIDASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 5 LEU A 143
TRP A 118
ILE A 119
ASN A  94
None
1.46A 4i00A-5wugA:
undetectable
4i00A-5wugA:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD6_A_TOYA501_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 9 ASP A 728
ILE A 733
VAL A 685
GLU A 737
GLU A 449
None
1.18A 4jd6A-5wugA:
0.0
4jd6A-5wugA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_MTLA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 6 GLU A 263
ASP A 174
ASP A 210
ARG A 180
None
1.42A 4kcnA-5wugA:
undetectable
4kcnA-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_A_9TPA601_1
(SERUM ALBUMIN)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 ALA A 451
TYR A 695
ILE A 627
ARG A 288
GLY A 286
None
1.15A 4l9qA-5wugA:
undetectable
4l9qA-5wugA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 11 ASN A  88
VAL A  89
ASN A 615
LEU A 612
ALA A  37
None
1.18A 4m83A-5wugA:
undetectable
4m83A-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_0
(NEURAMINIDASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 LEU A 620
ASP A 570
ARG A 576
GLU A 638
ARG A 635
None
1.37A 4mwvA-5wugA:
undetectable
4mwvA-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 VAL A 240
VAL A 226
ALA A  44
LEU A 254
VAL A 205
None
1.34A 4nc3A-5wugA:
undetectable
4nc3A-5wugA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 8 ALA A 166
ASP A 210
ILE A 209
ILE A 162
None
0.89A 4ndnB-5wugA:
undetectable
4ndnB-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_1
(PROTEASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 11 ALA A  43
ILE A 235
GLY A 232
ILE A 588
THR A 584
None
0.87A 4qgiA-5wugA:
undetectable
4qgiA-5wugA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_0
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 TYR A 414
GLU A 410
GLY A 412
PRO A 462
ALA A 365
None
1.25A 4wcxC-5wugA:
2.4
4wcxC-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_2
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 6 PRO A 301
HIS A 260
ILE A 214
VAL A 226
None
0.97A 4zj8A-5wugA:
3.4
4zj8A-5wugA:
11.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EQB_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 PHE A 637
ILE A 588
GLY A  80
GLY A  84
THR A 746
None
1.03A 5eqbA-5wugA:
undetectable
5eqbA-5wugA:
8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_A_SAMA301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 ASP A 683
ALA A 684
ASP A 171
GLY A 272
GLU A 275
None
1.38A 5hfjA-5wugA:
undetectable
5hfjA-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_2
(CDL2.2)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 MET A 778
LEU A 559
ILE A 815
ALA A 824
LEU A 819
None
1.15A 5ienB-5wugA:
1.8
5ienB-5wugA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 7 LEU A 243
TYR A  76
ARG A  78
LEU A 591
None
0.88A 5iy5A-5wugA:
undetectable
5iy5J-5wugA:
undetectable
5iy5A-5wugA:
undetectable
5iy5J-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA612_1
(PHIAB6 TAILSPIKE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 4 VAL A 881
THR A 883
GLU A 786
GLU A 556
None
1.27A 5jsdA-5wugA:
0.5
5jsdB-5wugA:
0.0
5jsdA-5wugA:
9.32
5jsdB-5wugA:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
3 / 3 VAL A 205
GLU A 140
GLU A 185
None
0.77A 5jsdB-5wugA:
undetectable
5jsdC-5wugA:
0.6
5jsdB-5wugA:
9.32
5jsdC-5wugA:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC611_1
(PHIAB6 TAILSPIKE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 4 GLU A 786
GLU A 556
VAL A 881
THR A 883
None
1.27A 5jsdA-5wugA:
0.5
5jsdC-5wugA:
0.6
5jsdA-5wugA:
9.32
5jsdC-5wugA:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 GLU A 796
LEU A 803
ASN A 765
ALA A 772
VAL A 533
None
1.43A 5kbwB-5wugA:
undetectable
5kbwB-5wugA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_1
(PROTEASE PR5-SQV)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 9 ALA A  43
ILE A 235
GLY A 232
ILE A 588
THR A 584
None
0.90A 5kr2A-5wugA:
undetectable
5kr2A-5wugA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_1
(PROTEASE PR5-SQV)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 9 ALA A  43
ILE A 235
GLY A 232
ILE A 588
THR A 584
None
0.93A 5kr2C-5wugA:
undetectable
5kr2C-5wugA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 7 LEU A 632
ILE A 162
MET A 203
TRP A 213
None
1.45A 5ljcA-5wugA:
undetectable
5ljcA-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M67_C_ACTC504_0
(ADENOSYLHOMOCYSTEINA
SE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 4 ASP A 728
ILE A 733
ARG A 692
ARG A 488
None
1.46A 5m67C-5wugA:
2.2
5m67C-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M6G_A_SORA711_0
(BETA-GLUCOSIDASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
6 / 12 ASP A 570
ARG A 635
LYS A 668
HIS A 669
MET A 712
GLU A 168
None
0.58A 5m6gA-5wugA:
19.2
5m6gA-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MQT_A_STIA302_1
(DEOXYCYTIDINE KINASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 VAL A 226
GLU A 346
PHE A 300
SER A 421
GLU A  54
None
1.19A 5mqtA-5wugA:
undetectable
5mqtA-5wugA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 GLY A 233
VAL A  89
PHE A  36
ILE A  42
ALA A  43
None
1.08A 5n0sA-5wugA:
undetectable
5n0sA-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 GLY A 233
VAL A  89
PHE A  36
ILE A  42
ALA A  43
None
1.04A 5n0tA-5wugA:
undetectable
5n0tA-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 GLY A 233
VAL A  89
PHE A  36
ILE A  42
ALA A  43
None
1.01A 5n0tB-5wugA:
undetectable
5n0tB-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 GLY A 233
VAL A  89
PHE A  36
ILE A  42
ALA A  43
None
1.01A 5n0wB-5wugA:
undetectable
5n0wB-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 GLY A 233
VAL A  89
PHE A  36
ILE A  42
ALA A  43
None
1.05A 5n0xA-5wugA:
undetectable
5n0xA-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 GLY A 233
VAL A  89
PHE A  36
ILE A  42
ALA A  43
None
1.03A 5n4iA-5wugA:
undetectable
5n4iA-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA303_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
3 / 3 GLU A 280
TYR A 279
ARG A 629
None
0.78A 5uunA-5wugA:
undetectable
5uunA-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
3 / 3 GLU A 280
TYR A 279
ARG A 629
None
0.80A 5uunB-5wugA:
undetectable
5uunB-5wugA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X80_C_SALC201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 7 VAL A  49
VAL A 347
GLY A 303
TYR A 304
None
0.96A 5x80C-5wugA:
undetectable
5x80D-5wugA:
undetectable
5x80C-5wugA:
30.62
5x80D-5wugA:
30.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 7 LEU A 243
TYR A  76
ARG A  78
LEU A 591
None
0.93A 5xdqA-5wugA:
undetectable
5xdqJ-5wugA:
undetectable
5xdqA-5wugA:
undetectable
5xdqJ-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 8 LEU A 243
TYR A  76
ARG A  78
LEU A 591
None
0.90A 5xdxN-5wugA:
undetectable
5xdxW-5wugA:
undetectable
5xdxN-5wugA:
undetectable
5xdxW-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 8 LEU A 243
TYR A  76
ARG A  78
LEU A 591
None
0.93A 5zcqN-5wugA:
undetectable
5zcqW-5wugA:
undetectable
5zcqN-5wugA:
undetectable
5zcqW-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEC_C_RBTC601_1
(SCAFFOLD PROTEIN D13)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
5 / 12 VAL A 205
PRO A 266
VAL A 298
PHE A 290
PRO A 255
None
1.37A 6becA-5wugA:
undetectable
6becB-5wugA:
undetectable
6becC-5wugA:
2.7
6becA-5wugA:
8.67
6becB-5wugA:
8.67
6becC-5wugA:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 7 ALA A 166
ASP A 210
ILE A 209
ILE A 162
None
0.84A 6fbnA-5wugA:
undetectable
6fbnA-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_1
(TYROSINE-PROTEIN
KINASE ABL1)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 5 TYR A 605
VAL A  49
PHE A  36
GLY A 574
None
1.33A 6hd4A-5wugA:
undetectable
6hd4A-5wugA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_S_PCFS603_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)
5wug BETA-GLUCOSIDASE
(Paenibacillus
barengoltzii)
4 / 7 GLY A 648
PHE A 650
VAL A 654
SER A 641
None
1.00A 6hu9S-5wugA:
undetectable
6hu9q-5wugA:
undetectable
6hu9S-5wugA:
undetectable
6hu9q-5wugA:
undetectable