SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wuj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q9R_A_BEZA203_0
(PROTEIN OF UNKNOWN
FUNCTION)		 5wuj FLAGELLAR MOTOR
SWITCH PROTEIN FLIG
(Helicobacter
pylori) 		4 / 5 LEU B  26
GLY B  35
ILE B  46
ILE B  49
 None
 0.77A 2q9rA-5wujB:
undetectable		 2q9rA-5wujB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDI_A_SAMA601_0
(METHYLTRANSFERASE)		 5wuj FLAGELLAR M-RING
PROTEIN
FLAGELLAR MOTOR
SWITCH PROTEIN FLIG
(Helicobacter
pylori;
Helicobacter
pylori) 		5 / 12 ILE B  81
PHE B  71
PHE B  72
THR A 540
ILE A 537
 None
 1.04A 3ndiA-5wujB:
undetectable		 3ndiA-5wujB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_2
(PROTEASE)		 5wuj FLAGELLAR M-RING
PROTEIN
FLAGELLAR MOTOR
SWITCH PROTEIN FLIG
(Helicobacter
pylori) 		5 / 11 LEU B  38
ALA A 549
ASP A 546
ILE A 556
ILE B  46
 None
 1.19A 3s53B-5wujB:
undetectable		 3s53B-5wujB:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)		 5wuj FLAGELLAR M-RING
PROTEIN
FLAGELLAR MOTOR
SWITCH PROTEIN FLIG
(Helicobacter
pylori) 		4 / 5 LEU B  38
ALA A 549
THR B  34
PHE A 552
 None
 1.40A 3vasB-5wujB:
undetectable		 3vasB-5wujB:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZP_A_CFFA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 5wuj FLAGELLAR M-RING
PROTEIN
FLAGELLAR MOTOR
SWITCH PROTEIN FLIG
(Helicobacter
pylori) 		5 / 9 ILE A 537
PHE B  71
MET B  18
LEU A 551
ILE A 548
 None
 1.49A 5mzpA-5wujA:
undetectable		 5mzpA-5wujA:
7.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_B_SAMB505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 5wuj FLAGELLAR M-RING
PROTEIN
FLAGELLAR MOTOR
SWITCH PROTEIN FLIG
(Helicobacter
pylori;
Helicobacter
pylori) 		5 / 12 GLY B  30
ILE B  27
TYR A 530
LEU B  68
GLY B  64
 None
GOL  B 201 (-4.5A)
None
None
None
 1.24A 6bp4B-5wujB:
undetectable		 6bp4B-5wujB:
undetectable