SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wut'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHF_A_FOLA187_0
(DIHYDROFOLATE
REDUCTASE)		 5wut ULAM111
(Flavobacterium
sp.) 		5 / 12 ALA A  87
PHE A  13
THR A  74
ILE A  72
LEU A  18
 None
 1.07A 1dhfA-5wutA:
undetectable		 1dhfA-5wutA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHF_B_FOLB187_0
(DIHYDROFOLATE
REDUCTASE)		 5wut ULAM111
(Flavobacterium
sp.) 		5 / 12 ALA A  87
PHE A  13
THR A  74
ILE A  72
LEU A  18
 None
 1.05A 1dhfB-5wutA:
undetectable		 1dhfB-5wutA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA501_1
(YKOF)		 5wut ULAM111
(Flavobacterium
sp.) 		4 / 8 PHE A  80
ILE A 228
ILE A 231
THR A  74
 None
 0.69A 1sbrA-5wutA:
undetectable		 1sbrA-5wutA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 5wut ULAM111
(Flavobacterium
sp.) 		4 / 7 PHE A  80
ILE A 228
ILE A 231
THR A  74
 None
 0.72A 1sbrB-5wutA:
undetectable		 1sbrB-5wutA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 5wut ULAM111
(Flavobacterium
sp.) 		3 / 3 HIS A 161
ASP A 229
ASN A  53
 None
 0.85A 1wg8B-5wutA:
undetectable		 1wg8B-5wutA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3A_B_TOPB1189_1
(DIHYDROFOLATE
REDUCTASE)		 5wut ULAM111
(Flavobacterium
sp.) 		5 / 10 ALA A  87
PHE A  13
THR A  74
ILE A  72
LEU A  18
 None
 1.20A 2w3aB-5wutA:
undetectable		 2w3aB-5wutA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_A_FOLA401_0
(DIHYDROFOLATE
REDUCTASE)		 5wut ULAM111
(Flavobacterium
sp.) 		5 / 12 ALA A  87
PHE A  13
THR A  74
ILE A  72
LEU A  18
 None
 1.08A 2w3bA-5wutA:
undetectable		 2w3bA-5wutA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DXY_A_SAMA1_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 5wut ULAM111
(Flavobacterium
sp.) 		5 / 11 GLU A  40
GLY A 209
GLY A 213
ILE A 208
ASP A 219
 None
 1.02A 3dxyA-5wutA:
undetectable		 3dxyA-5wutA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N0H_A_TOPA187_1
(DIHYDROFOLATE
REDUCTASE)		 5wut ULAM111
(Flavobacterium
sp.) 		5 / 11 ALA A  87
PHE A  13
THR A  74
ILE A  72
LEU A  18
 None
 1.12A 3n0hA-5wutA:
undetectable		 3n0hA-5wutA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 5wut ULAM111
(Flavobacterium
sp.) 		5 / 12 GLU A  40
GLY A 209
ASN A  38
ASP A 219
GLY A 214
 None
 1.34A 3ps9A-5wutA:
undetectable		 3ps9A-5wutA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA187_1
(DIHYDROFOLATE
REDUCTASE)		 5wut ULAM111
(Flavobacterium
sp.) 		5 / 12 ALA A  87
PHE A  13
THR A  74
ILE A  72
LEU A  18
 None
 1.13A 3s3vA-5wutA:
undetectable		 3s3vA-5wutA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IPM_A_ACTA503_0
(GH7 FAMILY PROTEIN)		 5wut ULAM111
(Flavobacterium
sp.) 		5 / 9 ALA A 100
GLU A 118
ASP A 120
GLU A 123
TRP A  98
 None
 1.14A 4ipmA-5wutA:
13.1		 4ipmA-5wutA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KEB_B_FOLB202_0
(DIHYDROFOLATE
REDUCTASE)		 5wut ULAM111
(Flavobacterium
sp.) 		5 / 12 ALA A  87
PHE A  13
THR A  74
ILE A  72
LEU A  18
 None
 1.13A 4kebB-5wutA:
undetectable		 4kebB-5wutA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M6K_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5wut ULAM111
(Flavobacterium
sp.) 		5 / 12 ALA A  87
PHE A  13
THR A  74
ILE A  72
LEU A  18
 None
 1.07A 4m6kA-5wutA:
undetectable		 4m6kA-5wutA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5F_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 5wut ULAM111
(Flavobacterium
sp.) 		5 / 12 ALA A  87
PHE A  13
THR A  74
ILE A  72
LEU A  18
 None
 1.14A 4x5fB-5wutA:
undetectable		 4x5fB-5wutA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5wut ULAM111
(Flavobacterium
sp.) 		4 / 8 THR A  70
TYR A  44
THR A  68
GLN A  66
 None
 1.42A 5tzoA-5wutA:
5.0		 5tzoA-5wutA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1471_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5wut ULAM111
(Flavobacterium
sp.) 		5 / 12 GLY A  64
GLU A  63
TYR A  67
ASN A  48
THR A  68
 None
 1.26A 5x7pB-5wutA:
4.2		 5x7pB-5wutA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_2
(-)		 5wut ULAM111
(Flavobacterium
sp.) 		4 / 5 THR A  74
THR A  70
HIS A  49
LEU A  56
 None
 1.40A 6gbnA-5wutA:
undetectable		 6gbnA-5wutA:
10.94