SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wvb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		8 / 9 TYR A  98
PHE A 129
GLY A 175
ASP A 215
MET A 283
TYR A 285
ASP A 286
TRP A 433
 NAG  A 504 (-3.7A)
NAG  A 505 (-4.5A)
NAG  A 504 (-3.7A)
NAG  A 504 (-3.8A)
NAG  A 503 (-4.0A)
NAG  A 504 (-4.5A)
NAG  A 504 (-3.5A)
NAG  A 504 (-3.6A)
 0.79A 1e9lA-5wvbA:
57.3		 1e9lA-5wvbA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1868_0
(FPRA)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		3 / 3 ALA A 320
HIS A 321
VAL A 324
 None
 0.45A 1lqtB-5wvbA:
undetectable		 1lqtB-5wvbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1425_0
(FPRA)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		3 / 3 ALA A 320
HIS A 321
VAL A 324
 None
 0.43A 1lquB-5wvbA:
undetectable		 1lquB-5wvbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		4 / 5 ILE A  95
ILE A 280
ILE A 422
LEU A 170
 None
 0.93A 1zgyA-5wvbA:
undetectable		 1zgyA-5wvbA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		9 / 11 TYR A  98
PHE A 129
GLY A 175
ASP A 215
MET A 283
TYR A 285
ASP A 286
TYR A 340
TRP A 433
 NAG  A 504 (-3.7A)
NAG  A 505 (-4.5A)
NAG  A 504 (-3.7A)
NAG  A 504 (-3.8A)
NAG  A 503 (-4.0A)
NAG  A 504 (-4.5A)
NAG  A 504 (-3.5A)
NAG  A 505 (-4.1A)
NAG  A 504 (-3.6A)
 0.63A 2a3aA-5wvbA:
11.8		 2a3aA-5wvbA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		8 / 11 TYR A  98
PHE A 129
GLY A 175
TRP A 176
ASP A 215
MET A 283
TYR A 285
TRP A 433
 NAG  A 504 (-3.7A)
NAG  A 505 (-4.5A)
NAG  A 504 (-3.7A)
NAG  A 503 (-3.3A)
NAG  A 504 (-3.8A)
NAG  A 503 (-4.0A)
NAG  A 504 (-4.5A)
NAG  A 504 (-3.6A)
 0.74A 2a3aA-5wvbA:
11.8		 2a3aA-5wvbA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2433_1
(CHITINASE)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		7 / 9 PHE A 129
GLY A 175
MET A 283
TYR A 285
ASP A 286
TYR A 340
TRP A 433
 NAG  A 505 (-4.5A)
NAG  A 504 (-3.7A)
NAG  A 503 (-4.0A)
NAG  A 504 (-4.5A)
NAG  A 504 (-3.5A)
NAG  A 505 (-4.1A)
NAG  A 504 (-3.6A)
 0.52A 2a3aB-5wvbA:
45.4		 2a3aB-5wvbA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		8 / 11 PHE A 129
GLY A 175
TRP A 176
ASP A 215
TYR A 285
ASP A 286
TYR A 340
TRP A 433
 NAG  A 505 (-4.5A)
NAG  A 504 (-3.7A)
NAG  A 503 (-3.3A)
NAG  A 504 (-3.8A)
NAG  A 504 (-4.5A)
NAG  A 504 (-3.5A)
NAG  A 505 (-4.1A)
NAG  A 504 (-3.6A)
 0.69A 2a3bA-5wvbA:
45.3		 2a3bA-5wvbA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		9 / 11 TYR A  98
PHE A 129
GLY A 175
ASP A 215
MET A 283
TYR A 285
ASP A 286
TYR A 340
TRP A 433
 NAG  A 504 (-3.7A)
NAG  A 505 (-4.5A)
NAG  A 504 (-3.7A)
NAG  A 504 (-3.8A)
NAG  A 503 (-4.0A)
NAG  A 504 (-4.5A)
NAG  A 504 (-3.5A)
NAG  A 505 (-4.1A)
NAG  A 504 (-3.6A)
 0.64A 2a3bA-5wvbA:
45.3		 2a3bA-5wvbA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		8 / 10 PHE A 129
GLY A 175
ASP A 215
MET A 283
TYR A 285
ASP A 286
TYR A 340
TRP A 433
 NAG  A 505 (-4.5A)
NAG  A 504 (-3.7A)
NAG  A 504 (-3.8A)
NAG  A 503 (-4.0A)
NAG  A 504 (-4.5A)
NAG  A 504 (-3.5A)
NAG  A 505 (-4.1A)
NAG  A 504 (-3.6A)
 0.53A 2a3bB-5wvbA:
45.3		 2a3bB-5wvbA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		10 / 12 TYR A  98
TRP A 102
PHE A 129
GLY A 175
ASP A 215
MET A 283
TYR A 285
ASP A 286
TYR A 340
TRP A 433
 NAG  A 504 (-3.7A)
NAG  A 506 ( 4.3A)
NAG  A 505 (-4.5A)
NAG  A 504 (-3.7A)
NAG  A 504 (-3.8A)
NAG  A 503 (-4.0A)
NAG  A 504 (-4.5A)
NAG  A 504 (-3.5A)
NAG  A 505 (-4.1A)
NAG  A 504 (-3.6A)
 0.65A 2a3cA-5wvbA:
11.9		 2a3cA-5wvbA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		9 / 12 TRP A 102
PHE A 129
GLY A 175
ASP A 215
MET A 283
TYR A 285
ASP A 286
TYR A 340
TRP A 433
 NAG  A 506 ( 4.3A)
NAG  A 505 (-4.5A)
NAG  A 504 (-3.7A)
NAG  A 504 (-3.8A)
NAG  A 503 (-4.0A)
NAG  A 504 (-4.5A)
NAG  A 504 (-3.5A)
NAG  A 505 (-4.1A)
NAG  A 504 (-3.6A)
 0.54A 2a3cB-5wvbA:
45.4		 2a3cB-5wvbA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		3 / 3 TRP A 475
ALA A 480
VAL A 478
 None
 0.74A 2izqA-5wvbA:
undetectable
2izqB-5wvbA:
undetectable		 2izqA-5wvbA:
undetectable
2izqB-5wvbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		6 / 9 TYR A  98
PHE A 129
GLY A 175
ASP A 215
TYR A 285
TRP A 433
 NAG  A 504 (-3.7A)
NAG  A 505 (-4.5A)
NAG  A 504 (-3.7A)
NAG  A 504 (-3.8A)
NAG  A 504 (-4.5A)
NAG  A 504 (-3.6A)
 0.97A 2uy4A-5wvbA:
19.3		 2uy4A-5wvbA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		6 / 11 TYR A  98
PHE A 129
GLY A 175
ASP A 215
TYR A 285
TRP A 433
 NAG  A 504 (-3.7A)
NAG  A 505 (-4.5A)
NAG  A 504 (-3.7A)
NAG  A 504 (-3.8A)
NAG  A 504 (-4.5A)
NAG  A 504 (-3.6A)
 1.10A 2xtkA-5wvbA:
20.5		 2xtkA-5wvbA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		6 / 10 TYR A  98
PHE A 129
GLY A 175
ASP A 215
TYR A 285
TRP A 433
 NAG  A 504 (-3.7A)
NAG  A 505 (-4.5A)
NAG  A 504 (-3.7A)
NAG  A 504 (-3.8A)
NAG  A 504 (-4.5A)
NAG  A 504 (-3.6A)
 1.04A 2xtkB-5wvbA:
20.3		 2xtkB-5wvbA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARQ_A_DM5A606_1
(CHITINASE A)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		4 / 6 TRP A 176
ASP A 286
TRP A 291
ARG A 342
 NAG  A 503 (-3.3A)
NAG  A 504 (-3.5A)
NAG  A 502 (-4.0A)
NAG  A 503 (-3.7A)
 0.59A 3arqA-5wvbA:
39.3		 3arqA-5wvbA:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		4 / 7 TRP A 176
ASP A 286
TRP A 291
ARG A 342
 NAG  A 503 (-3.3A)
NAG  A 504 (-3.5A)
NAG  A 502 (-4.0A)
NAG  A 503 (-3.7A)
 0.63A 3arrA-5wvbA:
40.0		 3arrA-5wvbA:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		4 / 7 TRP A 176
GLY A 260
ASP A 286
ARG A 342
 NAG  A 503 (-3.3A)
NAG  A 502 ( 3.9A)
NAG  A 504 (-3.5A)
NAG  A 503 (-3.7A)
 0.53A 3arrA-5wvbA:
40.0		 3arrA-5wvbA:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		4 / 7 GLY A 260
ASP A 286
TRP A 291
ARG A 342
 NAG  A 502 ( 3.9A)
NAG  A 504 (-3.5A)
NAG  A 502 (-4.0A)
NAG  A 503 (-3.7A)
 0.67A 3aruA-5wvbA:
39.8		 3aruA-5wvbA:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		9 / 11 PHE A 129
GLY A 175
TRP A 176
ASP A 215
MET A 283
TYR A 285
ASP A 286
TYR A 340
TRP A 433
 NAG  A 505 (-4.5A)
NAG  A 504 (-3.7A)
NAG  A 503 (-3.3A)
NAG  A 504 (-3.8A)
NAG  A 503 (-4.0A)
NAG  A 504 (-4.5A)
NAG  A 504 (-3.5A)
NAG  A 505 (-4.1A)
NAG  A 504 (-3.6A)
 0.69A 3g6mA-5wvbA:
45.5		 3g6mA-5wvbA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		9 / 11 TYR A  98
PHE A 129
GLY A 175
ASP A 215
MET A 283
TYR A 285
ASP A 286
TYR A 340
TRP A 433
 NAG  A 504 (-3.7A)
NAG  A 505 (-4.5A)
NAG  A 504 (-3.7A)
NAG  A 504 (-3.8A)
NAG  A 503 (-4.0A)
NAG  A 504 (-4.5A)
NAG  A 504 (-3.5A)
NAG  A 505 (-4.1A)
NAG  A 504 (-3.6A)
 0.67A 3g6mA-5wvbA:
45.5		 3g6mA-5wvbA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA427_1
(CHITINASE)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		5 / 5 TRP A 176
TYR A 218
MET A 283
ASP A 286
TRP A 291
 NAG  A 503 (-3.3A)
NAG  A 503 (-4.4A)
NAG  A 503 (-4.0A)
NAG  A 504 (-3.5A)
NAG  A 502 (-4.0A)
 0.77A 3g6mA-5wvbA:
45.5		 3g6mA-5wvbA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCD_B_LNRB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		5 / 12 TYR A 340
ASN A 298
VAL A 397
TYR A 285
VAL A 316
 NAG  A 505 (-4.1A)
None
None
NAG  A 504 (-4.5A)
None
 1.33A 3hcdB-5wvbA:
0.8		 3hcdB-5wvbA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		3 / 3 ALA A 480
VAL A 478
TRP A 475
 None
 0.73A 3l8lA-5wvbA:
undetectable
3l8lB-5wvbA:
undetectable		 3l8lA-5wvbA:
undetectable
3l8lB-5wvbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		3 / 3 LYS A 330
VAL A 324
HIS A 321
 None
 1.09A 3tj7A-5wvbA:
undetectable		 3tj7A-5wvbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		6 / 11 PHE A 129
GLY A 175
ASP A 215
TYR A 285
TYR A 340
TRP A 433
 NAG  A 505 (-4.5A)
NAG  A 504 (-3.7A)
NAG  A 504 (-3.8A)
NAG  A 504 (-4.5A)
NAG  A 505 (-4.1A)
NAG  A 504 (-3.6A)
 0.84A 3wqvA-5wvbA:
54.5		 3wqvA-5wvbA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		9 / 11 PHE A 129
GLY A 175
TRP A 176
MET A 283
TYR A 285
ASP A 286
TYR A 340
ARG A 342
TRP A 433
 NAG  A 505 (-4.5A)
NAG  A 504 (-3.7A)
NAG  A 503 (-3.3A)
NAG  A 503 (-4.0A)
NAG  A 504 (-4.5A)
NAG  A 504 (-3.5A)
NAG  A 505 (-4.1A)
NAG  A 503 (-3.7A)
NAG  A 504 (-3.6A)
 0.44A 3wqvA-5wvbA:
54.5		 3wqvA-5wvbA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		6 / 11 PHE A 129
GLY A 175
ASP A 215
TYR A 285
TYR A 340
TRP A 433
 NAG  A 505 (-4.5A)
NAG  A 504 (-3.7A)
NAG  A 504 (-3.8A)
NAG  A 504 (-4.5A)
NAG  A 505 (-4.1A)
NAG  A 504 (-3.6A)
 0.86A 3wqwA-5wvbA:
54.5		 3wqwA-5wvbA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		9 / 11 PHE A 129
GLY A 175
TRP A 176
MET A 283
TYR A 285
ASP A 286
TYR A 340
ARG A 342
TRP A 433
 NAG  A 505 (-4.5A)
NAG  A 504 (-3.7A)
NAG  A 503 (-3.3A)
NAG  A 503 (-4.0A)
NAG  A 504 (-4.5A)
NAG  A 504 (-3.5A)
NAG  A 505 (-4.1A)
NAG  A 503 (-3.7A)
NAG  A 504 (-3.6A)
 0.46A 3wqwA-5wvbA:
54.5		 3wqwA-5wvbA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA502_1
(CHITINASE)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		4 / 5 TRP A 102
GLY A 175
TRP A 176
PHE A 373
 NAG  A 506 ( 4.3A)
NAG  A 504 (-3.7A)
NAG  A 503 (-3.3A)
NAG  A 505 (-3.5A)
 0.95A 3wqwA-5wvbA:
54.5		 3wqwA-5wvbA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_2
(DIPEPTIDYL PEPTIDASE
4)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		3 / 3 PHE A 440
TYR A 367
TYR A 377
 None
 1.02A 4ffwA-5wvbA:
undetectable		 4ffwA-5wvbA:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NSB_A_AINA402_1
(CHITINASE-3-LIKE
PROTEIN 1)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		4 / 7 THR A 100
TRP A 102
ARG A 106
TRP A 433
 None
NAG  A 506 ( 4.3A)
None
NAG  A 504 (-3.6A)
 0.57A 4nsbA-5wvbA:
54.9		 4nsbA-5wvbA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_J_377J401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		4 / 6 ASN A 158
GLU A 145
TYR A 203
LEU A 171
 None
 1.20A 4twdI-5wvbA:
undetectable
4twdJ-5wvbA:
undetectable		 4twdI-5wvbA:
13.68
4twdJ-5wvbA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_P_EVPP2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		4 / 6 SER A 103
GLY A 174
ASP A 215
GLY A 130
 None
None
NAG  A 504 (-3.8A)
None
 0.78A 5cdnT-5wvbA:
undetectable
5cdnU-5wvbA:
undetectable		 5cdnT-5wvbA:
13.37
5cdnU-5wvbA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		4 / 6 SER A 103
GLY A 174
ASP A 215
GLY A 130
 None
None
NAG  A 504 (-3.8A)
None
 0.85A 5cdpA-5wvbA:
undetectable
5cdpB-5wvbA:
undetectable		 5cdpA-5wvbA:
13.37
5cdpB-5wvbA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		7 / 8 PHE A 129
GLY A 175
TRP A 176
TYR A 285
ASP A 286
ARG A 342
TRP A 433
 NAG  A 505 (-4.5A)
NAG  A 504 (-3.7A)
NAG  A 503 (-3.3A)
NAG  A 504 (-4.5A)
NAG  A 504 (-3.5A)
NAG  A 503 (-3.7A)
NAG  A 504 (-3.6A)
 0.50A 5gqbA-5wvbA:
42.2		 5gqbA-5wvbA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		5 / 12 PRO A 452
MET A 457
ILE A  95
LEU A 453
ILE A 117
 None
 1.17A 5tiwB-5wvbA:
undetectable		 5tiwB-5wvbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 5wvb CHITINASE
(Ostrinia
furnacalis) 		3 / 3 THR A 169
GLU A 115
ASN A 158
 None
 0.85A 6nj9K-5wvbA:
undetectable		 6nj9K-5wvbA:
undetectable