SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5wvg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AXW_A_MTXA732_1
(THYMIDYLATE SYNTHASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		5 / 12 LEU A 532
LEU A 642
GLY A 641
PHE A 639
ALA A 685
 None
 0.85A 1axwA-5wvgA:
undetectable		 1axwA-5wvgA:
12.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		7 / 9 TYR A 534
PHE A 565
GLY A 605
ASP A 645
MET A 713
ASP A 716
TRP A 864
 NAG  A1003 ( 4.2A)
NAG  A1003 ( 4.8A)
NAG  A1003 (-3.5A)
NAG  A1003 (-3.9A)
NAG  A1003 (-3.6A)
NAG  A1003 (-3.1A)
NAG  A1003 (-3.4A)
 0.96A 1e9lA-5wvgA:
55.8		 1e9lA-5wvgA:
47.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		7 / 9 TYR A 534
PHE A 565
GLY A 605
ASP A 645
MET A 713
TYR A 715
ASP A 716
 NAG  A1003 ( 4.2A)
NAG  A1003 ( 4.8A)
NAG  A1003 (-3.5A)
NAG  A1003 (-3.9A)
NAG  A1003 (-3.6A)
NAG  A1003 (-4.5A)
NAG  A1003 (-3.1A)
 0.82A 1e9lA-5wvgA:
55.8		 1e9lA-5wvgA:
47.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKP_A_NVPA999_1
(HIV-1 RT, A-CHAIN)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		5 / 11 LEU A 634
ASN A 640
VAL A 588
TYR A 584
LEU A 642
 None
 1.17A 1fkpA-5wvgA:
undetectable		 1fkpA-5wvgA:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		4 / 7 SER A 845
VAL A 863
GLY A 766
ILE A 861
 None
 0.87A 1gtnC-5wvgA:
undetectable
1gtnD-5wvgA:
undetectable		 1gtnC-5wvgA:
undetectable
1gtnD-5wvgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		5 / 11 PHE A 626
ALA A 630
LEU A 634
ILE A 562
ALA A 602
 None
 1.06A 1ha2A-5wvgA:
undetectable		 1ha2A-5wvgA:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SKX_A_RFPA1_2
(ORPHAN NUCLEAR
RECEPTOR PXR)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		4 / 5 PHE A 658
LEU A 568
MET A 623
LEU A 667
 None
 1.28A 1skxA-5wvgA:
undetectable		 1skxA-5wvgA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLS_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		5 / 12 LEU A 532
LEU A 642
GLY A 641
PHE A 639
ALA A 685
 None
 1.01A 1tlsA-5wvgA:
undetectable		 1tlsA-5wvgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLS_B_C2FB266_0
(THYMIDYLATE SYNTHASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		5 / 12 LEU A 532
LEU A 642
GLY A 641
PHE A 639
ALA A 685
 None
 0.99A 1tlsB-5wvgA:
undetectable		 1tlsB-5wvgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TSN_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		5 / 12 LEU A 532
LEU A 642
GLY A 641
PHE A 639
ALA A 685
 None
 1.03A 1tsnA-5wvgA:
undetectable		 1tsnA-5wvgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1300_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		5 / 11 GLY A 771
ALA A 831
LEU A 813
VAL A 828
HIS A 727
 None
 1.11A 1ukbA-5wvgA:
undetectable		 1ukbA-5wvgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		9 / 11 TYR A 534
PHE A 565
GLY A 605
ASP A 645
MET A 713
TYR A 715
ASP A 716
TYR A 770
TRP A 864
 NAG  A1003 ( 4.2A)
NAG  A1003 ( 4.8A)
NAG  A1003 (-3.5A)
NAG  A1003 (-3.9A)
NAG  A1003 (-3.6A)
NAG  A1003 (-4.5A)
NAG  A1003 (-3.1A)
NAG  A1002 (-4.2A)
NAG  A1003 (-3.4A)
 0.56A 2a3aA-5wvgA:
11.7		 2a3aA-5wvgA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		7 / 11 TYR A 534
PHE A 565
GLY A 605
TRP A 606
ASP A 645
MET A 713
TRP A 864
 NAG  A1003 ( 4.2A)
NAG  A1003 ( 4.8A)
NAG  A1003 (-3.5A)
NAG  A1004 (-3.4A)
NAG  A1003 (-3.9A)
NAG  A1003 (-3.6A)
NAG  A1003 (-3.4A)
 0.61A 2a3aA-5wvgA:
11.7		 2a3aA-5wvgA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2433_1
(CHITINASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		7 / 9 PHE A 565
GLY A 605
MET A 713
TYR A 715
ASP A 716
TYR A 770
TRP A 864
 NAG  A1003 ( 4.8A)
NAG  A1003 (-3.5A)
NAG  A1003 (-3.6A)
NAG  A1003 (-4.5A)
NAG  A1003 (-3.1A)
NAG  A1002 (-4.2A)
NAG  A1003 (-3.4A)
 0.34A 2a3aB-5wvgA:
43.6		 2a3aB-5wvgA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		8 / 11 PHE A 565
GLY A 605
TRP A 606
ASP A 645
TYR A 715
ASP A 716
TYR A 770
TRP A 864
 NAG  A1003 ( 4.8A)
NAG  A1003 (-3.5A)
NAG  A1004 (-3.4A)
NAG  A1003 (-3.9A)
NAG  A1003 (-4.5A)
NAG  A1003 (-3.1A)
NAG  A1002 (-4.2A)
NAG  A1003 (-3.4A)
 0.64A 2a3bA-5wvgA:
43.6		 2a3bA-5wvgA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		9 / 11 TYR A 534
PHE A 565
GLY A 605
ASP A 645
MET A 713
TYR A 715
ASP A 716
TYR A 770
TRP A 864
 NAG  A1003 ( 4.2A)
NAG  A1003 ( 4.8A)
NAG  A1003 (-3.5A)
NAG  A1003 (-3.9A)
NAG  A1003 (-3.6A)
NAG  A1003 (-4.5A)
NAG  A1003 (-3.1A)
NAG  A1002 (-4.2A)
NAG  A1003 (-3.4A)
 0.56A 2a3bA-5wvgA:
43.6		 2a3bA-5wvgA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		8 / 10 PHE A 565
GLY A 605
ASP A 645
MET A 713
TYR A 715
ASP A 716
TYR A 770
TRP A 864
 NAG  A1003 ( 4.8A)
NAG  A1003 (-3.5A)
NAG  A1003 (-3.9A)
NAG  A1003 (-3.6A)
NAG  A1003 (-4.5A)
NAG  A1003 (-3.1A)
NAG  A1002 (-4.2A)
NAG  A1003 (-3.4A)
 0.39A 2a3bB-5wvgA:
11.5		 2a3bB-5wvgA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		10 / 12 TYR A 534
TRP A 538
PHE A 565
GLY A 605
ASP A 645
MET A 713
TYR A 715
ASP A 716
TYR A 770
TRP A 864
 NAG  A1003 ( 4.2A)
NAG  A1001 (-4.0A)
NAG  A1003 ( 4.8A)
NAG  A1003 (-3.5A)
NAG  A1003 (-3.9A)
NAG  A1003 (-3.6A)
NAG  A1003 (-4.5A)
NAG  A1003 (-3.1A)
NAG  A1002 (-4.2A)
NAG  A1003 (-3.4A)
 0.59A 2a3cA-5wvgA:
11.8		 2a3cA-5wvgA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		9 / 12 TRP A 538
PHE A 565
GLY A 605
ASP A 645
MET A 713
TYR A 715
ASP A 716
TYR A 770
TRP A 864
 NAG  A1001 (-4.0A)
NAG  A1003 ( 4.8A)
NAG  A1003 (-3.5A)
NAG  A1003 (-3.9A)
NAG  A1003 (-3.6A)
NAG  A1003 (-4.5A)
NAG  A1003 (-3.1A)
NAG  A1002 (-4.2A)
NAG  A1003 (-3.4A)
 0.43A 2a3cB-5wvgA:
43.7		 2a3cB-5wvgA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		5 / 12 PHE A 626
LEU A 634
LEU A 601
ALA A 602
ILE A 603
 None
 1.15A 2bxpA-5wvgA:
undetectable		 2bxpA-5wvgA:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		6 / 12 LEU A 661
PHE A 613
LEU A 665
LEU A 642
ILE A 603
ALA A 685
 None
 1.41A 2bxqA-5wvgA:
undetectable		 2bxqA-5wvgA:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_B_D16B568_1
(THYMIDYLATE SYNTHASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		5 / 12 LEU A 532
LEU A 642
GLY A 641
PHE A 639
ALA A 685
 None
 0.79A 2kceB-5wvgA:
undetectable		 2kceB-5wvgA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGZ_D_COCD401_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		4 / 6 TYR A 648
TYR A 698
GLN A 756
ILE A 694
 NAG  A1004 (-4.7A)
None
None
None
 1.32A 2pgzD-5wvgA:
undetectable
2pgzE-5wvgA:
undetectable		 2pgzD-5wvgA:
18.93
2pgzE-5wvgA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		6 / 9 TYR A 534
PHE A 565
GLY A 605
ASP A 645
TYR A 715
TRP A 864
 NAG  A1003 ( 4.2A)
NAG  A1003 ( 4.8A)
NAG  A1003 (-3.5A)
NAG  A1003 (-3.9A)
NAG  A1003 (-4.5A)
NAG  A1003 (-3.4A)
 1.03A 2uy4A-5wvgA:
19.6		 2uy4A-5wvgA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		6 / 11 TYR A 534
PHE A 565
GLY A 605
ASP A 645
TYR A 715
TRP A 864
 NAG  A1003 ( 4.2A)
NAG  A1003 ( 4.8A)
NAG  A1003 (-3.5A)
NAG  A1003 (-3.9A)
NAG  A1003 (-4.5A)
NAG  A1003 (-3.4A)
 1.17A 2xtkA-5wvgA:
20.7		 2xtkA-5wvgA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		6 / 10 TYR A 534
PHE A 565
GLY A 605
ASP A 645
TYR A 715
TRP A 864
 NAG  A1003 ( 4.2A)
NAG  A1003 ( 4.8A)
NAG  A1003 (-3.5A)
NAG  A1003 (-3.9A)
NAG  A1003 (-4.5A)
NAG  A1003 (-3.4A)
 1.10A 2xtkB-5wvgA:
20.7		 2xtkB-5wvgA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARQ_A_DM5A606_1
(CHITINASE A)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		4 / 6 TRP A 606
ASP A 716
TRP A 721
ARG A 772
 NAG  A1004 (-3.4A)
NAG  A1003 (-3.1A)
NAG  A1005 (-3.8A)
NAG  A1004 (-3.1A)
 0.56A 3arqA-5wvgA:
40.8		 3arqA-5wvgA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		4 / 7 TRP A 606
ASP A 716
TRP A 721
ARG A 772
 NAG  A1004 (-3.4A)
NAG  A1003 (-3.1A)
NAG  A1005 (-3.8A)
NAG  A1004 (-3.1A)
 0.56A 3arrA-5wvgA:
40.8		 3arrA-5wvgA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		9 / 11 PHE A 565
GLY A 605
TRP A 606
ASP A 645
MET A 713
TYR A 715
ASP A 716
TYR A 770
TRP A 864
 NAG  A1003 ( 4.8A)
NAG  A1003 (-3.5A)
NAG  A1004 (-3.4A)
NAG  A1003 (-3.9A)
NAG  A1003 (-3.6A)
NAG  A1003 (-4.5A)
NAG  A1003 (-3.1A)
NAG  A1002 (-4.2A)
NAG  A1003 (-3.4A)
 0.57A 3g6mA-5wvgA:
43.5		 3g6mA-5wvgA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		9 / 11 TYR A 534
PHE A 565
GLY A 605
ASP A 645
MET A 713
TYR A 715
ASP A 716
TYR A 770
TRP A 864
 NAG  A1003 ( 4.2A)
NAG  A1003 ( 4.8A)
NAG  A1003 (-3.5A)
NAG  A1003 (-3.9A)
NAG  A1003 (-3.6A)
NAG  A1003 (-4.5A)
NAG  A1003 (-3.1A)
NAG  A1002 (-4.2A)
NAG  A1003 (-3.4A)
 0.60A 3g6mA-5wvgA:
43.5		 3g6mA-5wvgA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA427_1
(CHITINASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		5 / 5 TRP A 606
TYR A 648
MET A 713
ASP A 716
TRP A 721
 NAG  A1004 (-3.4A)
NAG  A1004 (-4.7A)
NAG  A1003 (-3.6A)
NAG  A1003 (-3.1A)
NAG  A1005 (-3.8A)
 0.66A 3g6mA-5wvgA:
43.5		 3g6mA-5wvgA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCD_B_LNRB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		5 / 12 TYR A 770
ASN A 728
VAL A 828
TYR A 715
VAL A 746
 NAG  A1002 (-4.2A)
None
None
NAG  A1003 (-4.5A)
None
 1.34A 3hcdB-5wvgA:
0.8		 3hcdB-5wvgA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_G_ACTG225_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		3 / 3 PRO A 733
LEU A 734
GLN A 826
 None
 0.63A 3hznG-5wvgA:
undetectable
3hznH-5wvgA:
undetectable		 3hznG-5wvgA:
undetectable
3hznH-5wvgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		4 / 7 PHE A 812
GLU A 808
ARG A 833
VAL A 838
 None
 1.37A 3jt3A-5wvgA:
undetectable
3jt3B-5wvgA:
undetectable		 3jt3A-5wvgA:
10.82
3jt3B-5wvgA:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		5 / 12 GLU A 800
ALA A 686
TRP A 538
GLY A 605
ASN A 711
 NAG  A1002 (-3.6A)
NAG  A1003 (-3.6A)
NAG  A1001 (-4.0A)
NAG  A1003 (-3.5A)
None
 1.34A 3jzjA-5wvgA:
undetectable		 3jzjA-5wvgA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		4 / 8 GLU A 811
PHE A 871
ARG A 796
PHE A 797
 None
 1.15A 3mjrD-5wvgA:
undetectable		 3mjrD-5wvgA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		4 / 7 PHE A 812
GLU A 808
ARG A 833
VAL A 838
 None
 1.40A 3n5vA-5wvgA:
undetectable
3n5vB-5wvgA:
undetectable		 3n5vA-5wvgA:
10.82
3n5vB-5wvgA:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		4 / 7 ARG A 833
VAL A 838
PHE A 812
GLU A 808
 None
 1.42A 3ufpA-5wvgA:
undetectable
3ufpB-5wvgA:
0.4		 3ufpA-5wvgA:
10.82
3ufpB-5wvgA:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		4 / 7 PHE A 812
GLU A 808
ARG A 833
VAL A 838
 None
 1.39A 3ufqA-5wvgA:
undetectable
3ufqB-5wvgA:
0.4		 3ufqA-5wvgA:
10.82
3ufqB-5wvgA:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		5 / 11 PHE A 565
GLY A 605
ASP A 645
TYR A 715
TRP A 864
 NAG  A1003 ( 4.8A)
NAG  A1003 (-3.5A)
NAG  A1003 (-3.9A)
NAG  A1003 (-4.5A)
NAG  A1003 (-3.4A)
 0.98A 3wqvA-5wvgA:
54.3		 3wqvA-5wvgA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		9 / 11 PHE A 565
GLY A 605
TRP A 606
MET A 713
TYR A 715
ASP A 716
TYR A 770
ARG A 772
TRP A 864
 NAG  A1003 ( 4.8A)
NAG  A1003 (-3.5A)
NAG  A1004 (-3.4A)
NAG  A1003 (-3.6A)
NAG  A1003 (-4.5A)
NAG  A1003 (-3.1A)
NAG  A1002 (-4.2A)
NAG  A1004 (-3.1A)
NAG  A1003 (-3.4A)
 0.30A 3wqvA-5wvgA:
54.3		 3wqvA-5wvgA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA502_1
(CHITINASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		4 / 4 TRP A 538
GLY A 605
TRP A 606
ALA A 607
 NAG  A1001 (-4.0A)
NAG  A1003 (-3.5A)
NAG  A1004 (-3.4A)
NAG  A1002 (-3.3A)
 0.43A 3wqvA-5wvgA:
54.3		 3wqvA-5wvgA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		5 / 11 PHE A 565
ASP A 645
TYR A 715
TYR A 770
TRP A 864
 NAG  A1003 ( 4.8A)
NAG  A1003 (-3.9A)
NAG  A1003 (-4.5A)
NAG  A1002 (-4.2A)
NAG  A1003 (-3.4A)
 0.98A 3wqwA-5wvgA:
54.3		 3wqwA-5wvgA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		9 / 11 PHE A 565
GLY A 605
TRP A 606
MET A 713
TYR A 715
ASP A 716
TYR A 770
ARG A 772
TRP A 864
 NAG  A1003 ( 4.8A)
NAG  A1003 (-3.5A)
NAG  A1004 (-3.4A)
NAG  A1003 (-3.6A)
NAG  A1003 (-4.5A)
NAG  A1003 (-3.1A)
NAG  A1002 (-4.2A)
NAG  A1004 (-3.1A)
NAG  A1003 (-3.4A)
 0.34A 3wqwA-5wvgA:
54.3		 3wqwA-5wvgA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA502_1
(CHITINASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		5 / 5 TRP A 538
GLY A 605
TRP A 606
ALA A 607
PHE A 803
 NAG  A1001 (-4.0A)
NAG  A1003 (-3.5A)
NAG  A1004 (-3.4A)
NAG  A1002 (-3.3A)
NAG  A1002 (-3.3A)
 0.92A 3wqwA-5wvgA:
54.3		 3wqwA-5wvgA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		4 / 7 PHE A 812
GLU A 808
ARG A 833
VAL A 838
 None
 1.39A 4caoA-5wvgA:
undetectable
4caoB-5wvgA:
undetectable		 4caoA-5wvgA:
10.82
4caoB-5wvgA:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		4 / 7 PHE A 812
GLU A 808
ARG A 833
VAL A 838
 None
 1.41A 4d31A-5wvgA:
undetectable
4d31B-5wvgA:
undetectable		 4d31A-5wvgA:
10.82
4d31B-5wvgA:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F5Z_A_BEZA302_0
(HALOALKANE
DEHALOGENASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		5 / 8 ASN A 552
PHE A 548
VAL A 866
LEU A 590
TYR A 880
 None
 1.42A 4f5zA-5wvgA:
undetectable		 4f5zA-5wvgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_D_C2FD302_0
(THYMIDYLATE SYNTHASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		5 / 11 LEU A 532
LEU A 642
GLY A 641
PHE A 639
ALA A 685
 None
 0.98A 4fogD-5wvgA:
undetectable		 4fogD-5wvgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_E_D16E301_1
(THYMIDYLATE SYNTHASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		5 / 12 GLU A 672
ILE A 631
LEU A 642
GLY A 641
PHE A 669
 None
 1.31A 4foxE-5wvgA:
undetectable		 4foxE-5wvgA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7U_D_YTZD802_1
(SEPIAPTERIN
REDUCTASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		4 / 8 PHE A 774
TRP A 837
PRO A 730
GLN A 826
 None
 0.92A 4j7uD-5wvgA:
undetectable		 4j7uD-5wvgA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_A_SAMA900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		5 / 12 TYR A 648
GLY A 605
GLY A 609
ASP A 643
ALA A 602
 NAG  A1004 (-4.7A)
NAG  A1003 (-3.5A)
None
None
None
 1.05A 4krhA-5wvgA:
2.3		 4krhA-5wvgA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NSB_A_AINA402_1
(CHITINASE-3-LIKE
PROTEIN 1)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		4 / 7 THR A 536
TRP A 538
ARG A 542
TRP A 864
 None
NAG  A1001 (-4.0A)
None
NAG  A1003 (-3.4A)
 0.56A 4nsbA-5wvgA:
53.9		 4nsbA-5wvgA:
38.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRY_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		4 / 8 GLN A 741
TYR A 748
SER A 690
PHE A 691
 None
None
NAG  A1005 ( 4.1A)
None
 1.04A 4wryA-5wvgA:
undetectable		 4wryA-5wvgA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRZ_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		4 / 8 GLN A 741
TYR A 748
SER A 690
PHE A 691
 None
None
NAG  A1005 ( 4.1A)
None
 1.02A 4wrzA-5wvgA:
undetectable		 4wrzA-5wvgA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		4 / 7 PHE A 812
GLU A 808
ARG A 833
VAL A 838
 None
 1.47A 5ad4A-5wvgA:
undetectable
5ad4B-5wvgA:
0.0		 5ad4A-5wvgA:
10.82
5ad4B-5wvgA:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		4 / 6 PHE A 812
GLU A 808
ARG A 833
VAL A 838
 None
 1.39A 5ad5A-5wvgA:
undetectable
5ad5B-5wvgA:
undetectable		 5ad5A-5wvgA:
10.82
5ad5B-5wvgA:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		4 / 7 ARG A 833
VAL A 838
PHE A 812
GLU A 808
 None
 1.42A 5ad6A-5wvgA:
0.0
5ad6B-5wvgA:
undetectable		 5ad6A-5wvgA:
10.82
5ad6B-5wvgA:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		7 / 8 PHE A 565
GLY A 605
TRP A 606
TYR A 715
ASP A 716
ARG A 772
TRP A 864
 NAG  A1003 ( 4.8A)
NAG  A1003 (-3.5A)
NAG  A1004 (-3.4A)
NAG  A1003 (-4.5A)
NAG  A1003 (-3.1A)
NAG  A1004 (-3.1A)
NAG  A1003 (-3.4A)
 0.45A 5gqbA-5wvgA:
42.9		 5gqbA-5wvgA:
8.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		4 / 7 LEU A 890
THR A 559
MET A 886
LEU A 853
 None
 1.14A 5jq7B-5wvgA:
undetectable		 5jq7B-5wvgA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		3 / 3 TYR A 563
ALA A 581
TYR A 584
 None
 0.86A 5uunB-5wvgA:
undetectable		 5uunB-5wvgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		5 / 12 ILE A 562
PHE A 613
GLY A 641
LEU A 573
PHE A 608
 None
 1.35A 5v5zA-5wvgA:
undetectable		 5v5zA-5wvgA:
10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_E_FFOE403_0
(THYMIDYLATE SYNTHASE)		 5wvg CHITINASE
(Ostrinia
furnacalis) 		5 / 12 LEU A 532
LEU A 642
GLY A 641
PHE A 639
ALA A 685
 None
 0.96A 6r2eE-5wvgA:
undetectable		 6r2eE-5wvgA:
undetectable