SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ww1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		6 / 12 TYR A 259
ARG A 371
ASP A 373
GLU A 402
HIS A 492
ASP A 493
 None
None
None
GLC  A 701 ( 4.8A)
None
GLC  A 701 ( 4.6A)
 0.80A 1dedB-5ww1A:
29.8		 1dedB-5ww1A:
8.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		7 / 12 TYR A 259
HIS A 307
ARG A 371
ASP A 373
GLU A 402
HIS A 492
ASP A 493
 None
None
None
None
GLC  A 701 ( 4.8A)
None
GLC  A 701 ( 4.6A)
 0.48A 1mxdA-5ww1A:
3.9		 1mxdA-5ww1A:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		4 / 8 LEU A 658
VAL A 692
GLY A 651
TRP A 646
 None
None
GLC  A 709 (-3.4A)
None
 0.89A 1s1xA-5ww1A:
undetectable		 1s1xA-5ww1A:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		5 / 12 LEU A 250
ILE A 554
TYR A 240
TYR A 271
HIS A 185
 CL  A 716 ( 3.9A)
None
None
None
None
 1.07A 1s9aB-5ww1A:
undetectable		 1s9aB-5ww1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		4 / 7 GLY A 369
HIS A 231
PRO A 171
LYS A 170
 None
 1.14A 1th6A-5ww1A:
undetectable		 1th6A-5ww1A:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		4 / 7 GLY A 369
HIS A 231
PRO A 171
LYS A 170
 None
 1.12A 2armA-5ww1A:
undetectable		 2armA-5ww1A:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_1
(PROTEASE)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		6 / 9 ALA A 179
VAL A 486
GLY A 369
ILE A 397
VAL A 483
ILE A 530
 None
 1.28A 2q5kA-5ww1A:
undetectable		 2q5kA-5ww1A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA426_0
(FERROCHELATASE)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		4 / 4 LEU A 410
PRO A 411
LEU A 414
ARG A 351
 None
 1.02A 2qd2A-5ww1A:
undetectable		 2qd2A-5ww1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_1
(HYPOTHETICAL PROTEIN
TTHA0223)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		4 / 5 TYR A 550
GLU A 243
ASP A 260
ASP A 239
 None
None
None
CA  A 717 (-3.1A)
 1.50A 2yqzA-5ww1A:
undetectable		 2yqzA-5ww1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_B_SAMB401_1
(HYPOTHETICAL PROTEIN
TTHA0223)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		4 / 5 TYR A 550
GLU A 243
ASP A 260
ASP A 239
 None
None
None
CA  A 717 (-3.1A)
 1.50A 2yqzB-5ww1A:
undetectable		 2yqzB-5ww1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		5 / 12 MET A 429
GLY A 428
THR A 177
PHE A 478
GLY A 468
 None
 1.23A 3ag4A-5ww1A:
1.4
3ag4B-5ww1A:
undetectable
3ag4T-5ww1A:
undetectable		 3ag4A-5ww1A:
undetectable
3ag4B-5ww1A:
undetectable
3ag4T-5ww1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		5 / 12 ARG A 371
ASP A 373
GLU A 402
HIS A 492
ASP A 493
 None
None
GLC  A 701 ( 4.8A)
None
GLC  A 701 ( 4.6A)
 0.63A 3aicA-5ww1A:
undetectable		 3aicA-5ww1A:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		5 / 12 ARG A 371
ASP A 373
GLU A 402
HIS A 492
ASP A 493
 None
None
GLC  A 701 ( 4.8A)
None
GLC  A 701 ( 4.6A)
 0.63A 3aicB-5ww1A:
7.3		 3aicB-5ww1A:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		6 / 12 ARG A 371
ASP A 373
GLU A 402
HIS A 492
ASP A 493
TYR A 259
 None
None
GLC  A 701 ( 4.8A)
None
GLC  A 701 ( 4.6A)
None
 0.60A 3aicC-5ww1A:
7.3		 3aicC-5ww1A:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		5 / 12 ARG A 371
ASP A 373
GLU A 402
HIS A 492
ASP A 493
 None
None
GLC  A 701 ( 4.8A)
None
GLC  A 701 ( 4.6A)
 0.72A 3aicD-5ww1A:
4.2		 3aicD-5ww1A:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		5 / 12 ARG A 371
ASP A 373
GLU A 402
ARG A 435
HIS A 492
 None
None
GLC  A 701 ( 4.8A)
GLC  A 702 ( 2.9A)
None
 0.73A 3aicE-5ww1A:
3.7		 3aicE-5ww1A:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		5 / 12 ARG A 371
ASP A 373
GLU A 402
HIS A 492
ASP A 493
 None
None
GLC  A 701 ( 4.8A)
None
GLC  A 701 ( 4.6A)
 0.65A 3aicE-5ww1A:
3.7		 3aicE-5ww1A:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		5 / 12 ARG A 371
ASP A 373
GLU A 402
HIS A 492
ASP A 493
 None
None
GLC  A 701 ( 4.8A)
None
GLC  A 701 ( 4.6A)
 0.65A 3aicF-5ww1A:
5.1		 3aicF-5ww1A:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		5 / 12 ARG A 371
ASP A 373
GLU A 402
HIS A 492
ASP A 493
 None
None
GLC  A 701 ( 4.8A)
None
GLC  A 701 ( 4.6A)
 0.64A 3aicG-5ww1A:
4.7		 3aicG-5ww1A:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		5 / 12 ARG A 371
ASP A 373
GLU A 402
HIS A 492
ASP A 493
 None
None
GLC  A 701 ( 4.8A)
None
GLC  A 701 ( 4.6A)
 0.68A 3aicH-5ww1A:
4.1		 3aicH-5ww1A:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAN_A_SVRA158_1
(UNCHARACTERIZED
PROTEIN AT3G22680)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		5 / 11 GLN A 484
VAL A 483
PRO A 482
PRO A 176
ILE A 397
 None
 1.27A 3ganA-5ww1A:
undetectable		 3ganA-5ww1A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		4 / 7 LEU A 599
SER A 485
GLY A 460
MET A 434
 None
 1.00A 3hcrB-5ww1A:
undetectable		 3hcrB-5ww1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA300_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		4 / 6 PHE A 532
TYR A 488
CYH A 491
PHE A 430
 None
 1.14A 3ltwA-5ww1A:
undetectable		 3ltwA-5ww1A:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_2
(HIV-1 PROTEASE)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		6 / 11 ALA A 179
VAL A 486
GLY A 369
ILE A 397
VAL A 483
ILE A 530
 None
 1.33A 3lzvB-5ww1A:
undetectable		 3lzvB-5ww1A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_1
(PROTEASE)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		6 / 10 ALA A 179
VAL A 486
GLY A 369
ILE A 397
VAL A 483
ILE A 530
 None
 1.25A 3nu6A-5ww1A:
undetectable		 3nu6A-5ww1A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_1
(PROTEASE)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		6 / 10 ALA A 179
VAL A 486
GLY A 369
ILE A 397
VAL A 483
ILE A 530
 None
 1.27A 3nujA-5ww1A:
undetectable		 3nujA-5ww1A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5P_A_TACA7101_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		5 / 12 ASN A 265
TYR A 353
PHE A 372
ILE A 354
TYR A 305
 None
 1.37A 3q5pA-5ww1A:
undetectable		 3q5pA-5ww1A:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		4 / 6 ILE A 300
TRP A 165
ILE A 282
TRP A 361
 None
 1.36A 3weoA-5ww1A:
12.6		 3weoA-5ww1A:
7.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TZC_D_EF2D505_1
(PROTEIN CEREBLON)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		4 / 8 TYR A 259
TRP A 257
HIS A 185
PHE A 532
 None
 1.13A 4tzcB-5ww1A:
undetectable
4tzcD-5ww1A:
undetectable		 4tzcB-5ww1A:
20.00
4tzcD-5ww1A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TZU_C_Y70C504_1
(PROTEIN CEREBLON)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		4 / 7 THR A 160
HIS A 366
TRP A 361
PHE A 370
 None
 1.37A 4tzuB-5ww1A:
undetectable
4tzuC-5ww1A:
undetectable		 4tzuB-5ww1A:
19.30
4tzuC-5ww1A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		4 / 4 SER A 270
ASP A 239
ASP A 310
ASP A 246
 None
CA  A 717 (-3.1A)
None
None
 1.25A 4uciA-5ww1A:
undetectable		 4uciA-5ww1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_ADNB2415_1
(RNA-DIRECTED RNA
POLYMERASE L)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		4 / 7 PHE A 611
ARG A 600
PHE A 601
TYR A 471
 None
 1.50A 4uciB-5ww1A:
undetectable		 4uciB-5ww1A:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		4 / 4 SER A 270
ASP A 239
ASP A 310
ASP A 246
 None
CA  A 717 (-3.1A)
None
None
 1.24A 4uciB-5ww1A:
undetectable		 4uciB-5ww1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_D_NOVD2000_1
(DNA GYRASE SUBUNIT B)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		5 / 12 SER A 345
ASP A 379
ILE A 386
ASP A 391
ILE A 358
 None
 1.38A 4uroD-5ww1A:
undetectable		 4uroD-5ww1A:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_B_1N1B601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		3 / 3 MET A 406
ASP A 373
PHE A 372
 GLC  A 702 ( 4.0A)
None
None
 1.06A 4xeyB-5ww1A:
undetectable		 4xeyB-5ww1A:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		5 / 12 ARG A 371
ASP A 373
GLU A 402
HIS A 492
ASP A 493
 None
None
GLC  A 701 ( 4.8A)
None
GLC  A 701 ( 4.6A)
 0.31A 5csyB-5ww1A:
4.2		 5csyB-5ww1A:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		3 / 3 ASP A 391
LEU A 173
ARG A 298
 None
 0.91A 5e8qA-5ww1A:
undetectable		 5e8qA-5ww1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		4 / 6 TYR A 365
GLY A 269
GLU A 268
ASP A 246
 None
None
CA  A 717 (-2.7A)
None
 1.34A 5emlA-5ww1A:
4.9		 5emlA-5ww1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HV1_A_RFPA902_1
(PHOSPHOENOLPYRUVATE
SYNTHASE)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		5 / 12 VAL A 461
TYR A 629
ALA A 520
VAL A 438
SER A 485
 None
 1.16A 5hv1A-5ww1A:
undetectable		 5hv1A-5ww1A:
6.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		4 / 7 GLY A 369
ASP A 394
HIS A 293
ASP A 368
 None
 1.02A 5nnwD-5ww1A:
undetectable		 5nnwD-5ww1A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		4 / 7 GLY A 369
ASP A 394
HIS A 293
ASP A 368
 None
 1.00A 5no9D-5ww1A:
undetectable		 5no9D-5ww1A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_A_CCSA14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		4 / 6 ASN A 341
LEU A 325
ARG A 331
GLY A 322
 None
 1.13A 5o4yA-5ww1A:
undetectable		 5o4yA-5ww1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		3 / 3 HIS A 366
GLU A 364
TRP A 165
 None
 1.16A 5odiD-5ww1A:
undetectable		 5odiD-5ww1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		3 / 3 HIS A 366
GLU A 364
TRP A 165
 None
 1.11A 5odqD-5ww1A:
undetectable		 5odqD-5ww1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		3 / 3 HIS A 366
GLU A 364
TRP A 165
 None
 1.09A 5odrD-5ww1A:
undetectable		 5odrD-5ww1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		4 / 6 ASP A 246
ARG A 249
LEU A 250
ASP A 251
 None
None
CL  A 716 ( 3.9A)
None
 1.14A 5tdzA-5ww1A:
undetectable		 5tdzA-5ww1A:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_G_EF2G501_1
(PROTEIN CEREBLON)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		4 / 7 HIS A 366
TRP A 361
PHE A 370
THR A 160
 None
 1.32A 5yj0G-5ww1A:
undetectable
5yj0Y-5ww1A:
undetectable		 5yj0G-5ww1A:
17.05
5yj0Y-5ww1A:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_T_EF2T501_1
(PROTEIN CEREBLON)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		4 / 7 THR A 160
HIS A 366
TRP A 361
PHE A 370
 None
 1.31A 5yj0k-5ww1A:
undetectable
5yj0t-5ww1A:
undetectable		 5yj0k-5ww1A:
17.05
5yj0t-5ww1A:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_G_6ELG501_0
(PROTEIN CEREBLON)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		4 / 8 HIS A 366
TRP A 361
PHE A 370
THR A 160
 None
 1.34A 5yj1G-5ww1A:
undetectable
5yj1Y-5ww1A:
undetectable		 5yj1G-5ww1A:
undetectable
5yj1Y-5ww1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_T_6ELT501_0
(PROTEIN CEREBLON)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		4 / 8 THR A 160
HIS A 366
TRP A 361
PHE A 370
 None
 1.36A 5yj1k-5ww1A:
undetectable
5yj1t-5ww1A:
undetectable		 5yj1k-5ww1A:
undetectable
5yj1t-5ww1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		5 / 12 TYR A 259
HIS A 307
ASP A 373
HIS A 492
ASP A 493
 None
None
None
None
GLC  A 701 ( 4.6A)
 0.46A 6ag0A-5ww1A:
23.4		 6ag0A-5ww1A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_E_HISE402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		5 / 9 VAL A  87
GLY A 121
LEU A 122
THR A 152
CYH A 119
 None
 1.27A 6czmD-5ww1A:
undetectable
6czmE-5ww1A:
undetectable		 6czmD-5ww1A:
undetectable
6czmE-5ww1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_F_HISF402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		5 / 10 VAL A  87
GLY A 121
LEU A 122
THR A 152
CYH A 119
 None
 1.26A 6czmE-5ww1A:
undetectable
6czmF-5ww1A:
undetectable		 6czmE-5ww1A:
undetectable
6czmF-5ww1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_1
(-)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		5 / 12 ASP A 493
ASP A 302
LEU A 374
GLY A 401
PHE A 532
 GLC  A 701 ( 4.6A)
None
None
None
None
 1.49A 6gbnB-5ww1A:
undetectable		 6gbnB-5ww1A:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5ww1 PULULLANASE
(Paenibacillus
barengoltzii) 		4 / 5 LEU A  56
TYR A  57
ILE A  35
GLY A  44
 None
 0.84A 6hd6A-5ww1A:
undetectable		 6hd6A-5ww1A:
20.00